31 Results for "

SV40

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "SV40" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P70658A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Neutrophil gelatinase-associated lipocalin; NGAL; Lipocalin-2; SV-40-induced 24P3 protein; Siderocalin LCN2; p25; LCN2
Species:  
Source:  
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3
3 Cited Publications
Cat. No.: HY-P1876
CAS No.: 95088-49-6
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the SV40 large T antigen, which mediates the binding of karyophilic proteins to importin α. NLS (PKKKRKV) serves as a method to enhance nuclear entry in the field of gene transfer research .
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3
3 Cited Publications
Cat. No.: HY-P1876B
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

NLS (PKKKRKV) hydrochloride is the hydrochloride form of NLS (PKKKRKV) (HY-P1876). NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen), that mediates binding of the karyophilic protein to importin α. NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research .
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2
2 Cited Publications
Cat. No.: HY-116683
CAS No.: 831217-43-7
Purity:  98.55%
Synonyms: MAL2-11B
Target:  

HSP DNA/RNA Synthesis

Research Areas:  

Infection Cancer

116-9e (MAL2-11B) is a Hsp70 co-chaperone DNAJA1 inhibitor. 116-9e inhibits Simian Virus 40 (SV40) replication and DNA synthesis. 116-9e inhibits tumor antigen (TAg)’s endogenous ATPase activity and the TAg-mediated activation of Hsp70 .
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2
2 Cited Publications
Cat. No.: HY-P83511
Synonyms: Large T antigen; LT; LT-AG

Host:  

Rabbit

Application:  

WB, ICC/IF, IP

Reactivity:  

Species independent

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1
1 Cited Publications
Cat. No.: HY-P81284A
Synonyms: LCN2; 24p3; MSFI; NGAL; Lipocalin-2; p25; Siderocalin; SV40 induced 24P3 protein; Uterocalin

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human

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1
1 Cited Publications
Cat. No.: HY-P70658
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Neutrophil gelatinase-associated lipocalin; NGAL; Lipocalin-2; SV-40-induced 24P3 protein; Siderocalin LCN2; p25; LCN2
Species:  
Source:  
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Cat. No.: HY-P0310
CAS No.: 163815-24-5
Target:  

Peptides

Research Areas:  

Infection

SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus.
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Cat. No.: HY-P1877A
Target:  

Peptides

Research Areas:  

Cancer

SV40 T-Ag-derived NLS peptide TFA is a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus .
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Cat. No.: HY-P3827
CAS No.: 104914-40-1
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly is a13-mer synthetic peptide containing seven amino acids homologous to SV40 T antigen. Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly is capable of inducing nuclear transport .
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Cat. No.: HY-119098
CAS No.: 827591-02-6
Purity:  99.8%
Target:  

EBV HPV

Research Areas:  

Infection

GSK983 is a broad-spectrum antiviral agent. GSK983 inhibits the replication of adenovirus-5 (Ad-5) and polyoma virus SV40. GSK983 inhibits the growth of cell lines immortalized by EBV, HTLV1, HPV. GSK983 induces the expression of interferon-stimulated genes .
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Cat. No.: HY-P1877
CAS No.: 105425-98-7
Target:  

Peptides

Research Areas:  

Cancer

SV40 T-Ag-derived NLS peptide is a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus .
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Cat. No.: HY-W048513
CAS No.: 60129-59-1
7-Deaza-2'-deoxyadenosine is an isosteric dATP analog of 2'-deoxyadenosine. 7-Deaza-2'-deoxyadenosine is recognized by various DNA polymerases and incorporated into DNA strands as a substrate. 7-Deaza-2'-deoxyadenosine undergoes a bioorthogonal inverse electron demand Diels-Alder reaction with tetrazine-modified molecules, enabling site-specific labeling of DNA, surface antibody immobilization and intracellular fluorescent labeling. 7-Deaza-2'-deoxyadenosine reduces the DNA curvature of d(A6)·d(T6) fragments and the stability of DNA/RNA double helices, and leads to decreased antisense activity against SV40 T Antigen. 7-Deaza-2'-deoxyadenosine finds application in the research field of SV40 T Antigen-related cancers .
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Cat. No.: HY-124429
CAS No.: 599151-35-6
Purity:  99.11%
Target:  

ERK

Research Areas:  

Cancer

FQI1 is a Late SV40 Factor (LSF) inhibitor. FQI1 inhibits cell proliferation, with IC50s of 3, 0.79, 6.3 μM for NIH/3T3, HeLa, A549 cells. FQI1 can be used for cancer research .
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Cat. No.: HY-W414548
CAS No.: 4725-24-0
7α,27-Dihydroxycholesterol is an oxysterol, a human metabolite, and a ligand for EBI2 (GPR183), which is involved in lipid synthesis. 7α,27-Dihydroxycholesterol mediates the chemotaxis of cells expressing EBI2. 7α,27-Dihydroxycholesterol can be converted into 7α,27-dihydroxy-4-cholesten-3-one (HY-W414457), thereby inhibiting HMG-CoA reductase (HMGCR), the rate-limiting enzyme in cholesterol synthesis .
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Cat. No.: HY-P1876A
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

NLS (PKKKRKV) TFA is the TFA form of NLS (PKKKRKV) (HY-P1876). NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen), that mediates binding of the karyophilic protein to importin α. NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research .
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Cat. No.: HY-114646
CAS No.: 403646-00-4
TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter .
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Cat. No.: HY-15865
CAS No.: 146478-74-2
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

FR901463 is a potent anti-cancer agent and can be used for cancer research. FR901463 enhances the transcriptional activity of the promoter of SV40 DNA virus .
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Cat. No.: HY-126311
CAS No.: 331443-00-6
Synonyms: 3,4,5,4'-Tetrahydroxystibene
Research Areas:  

Cancer

4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene), a Resveratrol (HY-16561) analog, differentially induces pro-apoptotic p53/Bax gene expression. 4-Hydroxyresveratrol induces apoptosis in SV40 virally transformed WI38 cells (WI38VA) cells, but not in WI38 cells. 4-Hydroxyresveratrol significantly induces the expression of p53, GADD45 and Bax genes and concomitantly suppresses the expression of bcl-2 gene in WI38VA .
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Cat. No.: HY-P1566
CAS No.: 395069-92-8
Target:  

HIV

Research Areas:  

Infection

MPG, HIV related is 27-aa peptide, derived from both the nuclear localisation sequence of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41 and is a potent delivery agent for the generalised delivery of nucleic acids and of oligonucleotides into cultured cells.
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