39 Results for "

Spiro

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "Spiro" in MCE Product Catalog:

9
9 Cited Publications
Cat. No.: HY-116788
CAS No.: 297180-15-5
Purity:  99.75%
Target:  

Bacterial

Research Areas:  

Infection

Lipofermata is a fatty acid transport protein 2 (FATP2) inhibitor. Lipofermata shows fatty acid transport inhibition with an IC50 of 4.84 μM in Caco-2 cells. Lipofermata, an analog of spiro-indoline-thadiazole, shows zinc-specific suppression of antibacterial activity. Lipofermata perturbs zinc homeostasis in E. coli K-12 with a MIC of 16 μM .
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1
1 Cited Publications
Cat. No.: HY-D1601
CAS No.: 98907-26-7
N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu 2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu 2+ in biological systems with λex/em=495/516 nm . N-Aminofluorescein can be used to measure the concentration of copper ions in cells .
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Cat. No.: HY-136645
CAS No.: 1965316-82-8
Research Areas:  

Cancer

EP4 receptor antagonist 2 (Compound 8) is a tricyclic spiro-based EP4 receptor antagonist with microsomal stability .
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Cat. No.: HY-134775
CAS No.: 1247001-12-2
Purity:  99.94%
Research Areas:  

Cancer

PLK4-IN-1 is a spiro cyclopropyl indolinone compound and PLK4 inhibitor with inhibitory activity against Aurora A and Aurora B kinases .PLK4-IN-1 can be used for the research of cancer .
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Cat. No.: HY-W025445
CAS No.: 207739-72-8
Research Areas:  

Others

Spiro-MeOTAD is a high performance hole transport layer material. Spiro-MeOTAD can be used in highly efficient perovskite solar cells .
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Cat. No.: HY-150701
CAS No.: 869974-19-6
Purity:  99.77%
INCB13739 is an orally active, potent, selective and tissue-specific11β-HSD1 (11β-hydroxysteroid dehydrogenase 1) inhibitor, with IC50 values of 3.2 nM (11β-HSD1 enzymatic) and 1.1 nM (11β-HSD1 PBMC), respectively. INCB13739 can be used for type 2 diabetes mellitus (T2DM) and obesity research .
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Cat. No.: HY-W058501
CAS No.: 1087798-38-6
Target:  

PROTAC Linkers

Research Areas:  

Cancer

6-((tert-Butoxycarbonyl)amino)spiro[3.3]heptane-2-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
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Cat. No.: HY-W126577
CAS No.: 1808253-04-4
Target:  

PROTAC Linkers

Research Areas:  

Cancer

NH2-spiro[3.3]heptane-methyl formate is a PROTAC linker that can be used in the synthesis of PROTACs.
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Cat. No.: HY-178040
Insecticidal agent 26 (Compound A11), a spiro insecticidal agent, is a dual-functional inhibitor of pest Acetyl-CoA carboxylase (ACC) and Pyruvate carboxylase (PC). Insecticidal agent 26 has potent insecticidal activity against Sogatella furcifera with a LC50 of 11.0  μg/mL, with significant biosafety to bees. Insecticidal agent 26 can be used for management of white-backed planthoppers (WBPs) .
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Cat. No.: HY-P1193
CAS No.: 129623-01-4
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

GR 82334 is a potent and specific reversible tachykinin NK1 receptor antagonist . GR 82334 inhibits substance P-induced sensitization by blocking SP NK1 receptors in naked mole-rats .
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Cat. No.: HY-134775A
CAS No.: 1247001-86-0
Research Areas:  

Cancer

PLK4-IN-3 is a less active absolute stereochemistry of PLK4-IN-1. PLK4-IN-1 is a spiro cyclopropyl indolinone compound and PLK4 inhibitor with inhibitory activity against Aurora A and Aurora B kinases .PLK4-IN-1 can be used for the research of cancer .
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Cat. No.: HY-137971
CAS No.: 1616622-10-6
Target:  

Ras

(±)-Spiro-oxanthromicin A (Compound 4), a polyketide, is a K-Ras inhibitor with an IC50 of 26.7  μM. (±)-Spiro-oxanthromicin A can be isolated from soil-derived Streptomyces sp. (±)-Spiro-oxanthromicin A can mislocalize oncogenic mutant K-Ras from the plasma membrane of intact MDCK cells. (±)-Spiro-oxanthromicin A can be used for cancers research .
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Cat. No.: HY-W102669
CAS No.: 82683-51-0
Target:  

Drug Intermediate

Research Areas:  

Cancer

Spiro[4.5]decane-7,9-dione (Compound 2e) is a cyclic 1,3-diketone. Spiro[4.5]decane-7,9-dione can be used in the study of glioma tumors .
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Cat. No.: HY-W056839
CAS No.: 37942-79-3
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Dimethyl spiro[3.3]heptane-2,6-dicarboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
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Cat. No.: HY-169489
Target:  

PROTAC Linkers

Research Areas:  

Cancer

2F-PYR-Pip-spiro[3.3]heptane-acid is a PROTAC linker. 2F-PYR-Pip-spiro[3.3]heptane-acid can be used in the synthesis of PROTACs (e.g. HY-169272) .
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Cat. No.: HY-159540
Research Areas:  

Cancer

(S,R,S)-AHPC-O-Spiro-CO is an E3 ligase ligand-linker conjugate.
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Cat. No.: HY-159478
Target:  

PROTAC Linkers

Research Areas:  

Cancer

6-(4-Methoxyphenyl)spiro[3.3]heptane-2-carboxylic acid is a PROTAC linker.
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Cat. No.: HY-169490
Research Areas:  

Cancer

SMARCA2 ligand-13 PYR-Pip-spiro[3.3]heptane-acid is a conjugate generated by linking a target protein ligand (HY-44824) to a linker (HY-169489). SMARCA2 ligand-13 PYR-Pip-spiro[3.3]heptane-acid can be used in the synthesis of PROTACs (e.g. PROTAC SMARCA2 degrader-21 (HY-169272)) .
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Cat. No.: HY-W057101
CAS No.: 170508-14-2
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Methyl 6-{[(tert-butoxy)carbonyl]amino}spiro[3.3]heptane-2-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
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