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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Statins
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Statins" in MCE Product Catalog:
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73 Publications Verification
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Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver.
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1 Cited Publications
Synonyms: (±)-Mevalonolactone; Mevalolactone
Category:
Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology
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HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis .
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Synonyms: Piperazine estrone sulfate; Estrone sulfate piperazine salt
Cat. No.: HY-17408R
CAS No.: 73573-88-3
Synonyms: Compactin(Standard); ML236B (Standard)
Research Areas:
Infection Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Mevastatin (Standard) is the analytical standard of Mevastatin. This product is intended for research and analytical applications. Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agent, and induces apoptosis, arrests cancer cells in G0/G1 phase. Mevastatin also increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. Mevastatin has antitumor activity and has the potential for cardiovascular diseases treatment .
Cat. No.: HY-120757
CAS No.: 153314-49-9
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Cat. No.: HY-107855R
CAS No.: 674-26-0
Synonyms: (±)-Mevalonolactone (Standard); Mevalolactone (Standard)
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Cat. No.: HY-138166S
Cat. No.: HY-138166R
CAS No.: 503610-43-3
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Rosuvastatin lactone (Standard) is the analytical standard of Rosuvastatin lactone. This product is intended for research and analytical applications. Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A), a statin lipid-lowering agent and HMG-CoA inhibitor. Rosuvastatin lactone exhibits endothelium-independent and HMG-CoA reductase-independent vasorelaxant activity in rat aortic rings, and its vasorelaxant effect is jointly mediated by NO produced by inducible nitric oxide synthase (iNOS) located in vascular smooth muscle and activation of potassium channels. Rosuvastatin lactone itself has no lipid-lowering effect .
Synonyms: Piperazine estrone sulfate (Standard); Estrone sulfate piperazine salt (Standard)
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Cat. No.: HY-107855S2
CAS No.: 53771-22-5
Synonyms: (±)-Mevalonolactone-13C; Mevalolactone-13C
Cat. No.: HY-107855S4
CAS No.: 287111-36-8
Synonyms: (±)-Mevalonolactone-13C2; Mevalolactone-13C2
Cat. No.: HY-W752587
CAS No.: 349553-98-6
Synonyms: (±)-Mevalonolactone-d4; Mevalolactone-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
