1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Lapaquistat

Lapaquistat (Synonyms: T-91485)

Cat. No.: HY-14925
Handling Instructions

Lapaquistat (T-91485), a cholesterol biosynthesis inhibitor, is the active metabolite of TAK-475. Lapaquistat can decrease statin-induced myotoxicity in lipid-lowering therapy.

For research use only. We do not sell to patients.

Lapaquistat Chemical Structure

Lapaquistat Chemical Structure

CAS No. : 189059-71-0

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Description

Lapaquistat (T-91485), a cholesterol biosynthesis inhibitor, is the active metabolite of TAK-475. Lapaquistat can decrease statin-induced myotoxicity in lipid-lowering therapy[1].

IC50 & Target

Cholesterol biosynthesis[1]

Molecular Weight

603.10

Formula

C₃₁H₃₉ClN₂O₈

CAS No.

189059-71-0

SMILES

O=C(O)CC1CCN(C(C[[email protected]@H]2C(N(CC(C)(C)CO)C3=CC=C(Cl)C=C3[[email protected]@H](C4=CC=CC(OC)=C4OC)O2)=O)=O)CC1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Lapaquistat
Cat. No.:
HY-14925
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