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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
TGFβ-R2
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "TGFβ-R2" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P700785
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFB2; Transforming Growth Factor, Beta 2; Transforming Growth Factor Beta 2; BSC-1 Cell Growth Inhibitor; Glioblastoma-Derived T-Cell Suppressor Factor; TGF-Beta2; Transforming Growth Factor Beta-2 Proprotein; Polyergin; Prepro-Transforming Growth Factor
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P78524
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kinase; TBR-Ii; TGF-Beta Receptor Type IIB; TGFR-2; TGF-Beta Receptor Type II; TBRII; TGFbeta-RII; Transforming Growth Factor, Beta Receptor II (70/80kDa); LDS1B; Transforming Growth Factor-Beta Receptor Type II; LDS2B; Transforming Growth Factor Beta Receptor II; TAAD2; TbetaR-II; AAT3; Transforming Growth Factor, Beta Receptor II Epsilon; FAA3; Transforming Growth Factor, Beta Receptor II Alpha; LDS2; Transforming Growth Factor, Beta Receptor II Delta; RIIC; Transforming Growth Factor Beta Receptor 2; Transforming Growth Factor Beta Receptor Type IIC
Species:
Human
Source:
HEK293
Cat. No.: HY-117887
CAS No.: 2141955-96-4
Synonyms: BLU-782; IPN-60130; ALK2-IN-1
Target:
Research Areas:
Fidrisertib (BLU-782) is the orally active inhibitor for activin receptor-like kinase 2 (ALK2) that inhibits ALK2 R206H, ALK2, ALK1, ALK6, ALK3, ALK4, TGFβR2 and ALK5 with IC50s of 0.2, 0.6, 3, 24, 45, 65, 67 and 155 nM, respectively [2].
Cat. No.: HY-W107024
CAS No.: 2001559-19-7
Target:
Research Areas:
BMS-986260, an immuno-oncology agent, is a potent, selective, and orally active TGFβR1 inhibitor (IC50=1.6 nM). BMS-986260 displays exquisite selectivity for TGFβR1 over its isozyme TGFβR2, as well as in a panel of more than 200 kinases examined. BMS-986260 inhibits TGFβ mediated nuclear translocation of pSMAD2/3 in MINK and NHLF cells lines with an IC50 of 350 nM and 190 nM, respectively .
Cat. No.: HY-P990009
CAS No.: 2649854-92-0
Synonyms: NIS-793
Target:
Research Areas:
Cat. No.: HY-E70867
Target:
Research Areas:
TGF-β is a pleiotropic multifunctional cytokine that regulates many cellular processes, such as cell growth, differentiation, apoptosis and cellular homeostasis. Before exerting the biological effects within cells, TGF-β first requires extracellular activation, namely binds to its type II receptor (TGFβR2) and promotes the phosphorylation. TGFβR1 plays an important role in TGF-β signaling transduction and serves as a tumor suppressor. TGFβR2 Recombinant Human Active Protein Kinase is a recombinant TGFβR2 protein that can be used to study TGFβR2-related functions .
Cat. No.: HY-P78800
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:
Human
Source:
HEK293
Cat. No.: HY-P78801
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P78215
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
