183 Results for "

Uracil mustard

" in MedChemExpress (MCE) Product Catalog:
Products (183)

183 Results for "Uracil mustard" in MCE Product Catalog:

352
352 Publications Verification
Cat. No.: HY-90006
CAS No.: 51-21-8
Synonyms: 5-FU
5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
loading...
    loading...
81
81 Cited Publications
Cat. No.: HY-17420
CAS No.: 50-18-0
Research Areas:  

Cancer

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.
loading...
    loading...
81
81 Cited Publications
Cat. No.: HY-17420A
CAS No.: 6055-19-2
Synonyms: Cyclophosphamide monohydrate
Research Areas:  

Cancer

Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
loading...
    loading...
22
22 Cited Publications
Cat. No.: HY-B1449
CAS No.: 58-96-8
Synonyms: β-Uridine
Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond .
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-137316A
CAS No.: 1566-15-0
Purity:  ≥98.0%
Research Areas:  

Cancer

Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-129046
CAS No.: 9001-99-4
Synonyms: Ribonuclease A; EC 4.6.1.18; RNase A
Research Areas:  

Others

RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-I0960
CAS No.: 66-22-8
Uracil is a pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA base damage that results from the spontaneous or chemically induced deamination of cytosine and is mutagenic at the level of replication. Uracil could potentially alter transcriptional fidelity, resulting in production of mutant proteins .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-13593
CAS No.: 305-03-3
Purity:  98.76%
Synonyms: CB-1348; WR-139013
Research Areas:  

Neurological Disease Cancer

Chlorambucil (CB-1348), an orally active antineoplastic agent, is a CNS-penetrant bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-113063
CAS No.: 1460-34-0
Purity:  99.31%
3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-W017386
CAS No.: 3715-31-9
3-Methyl-2-oxovaleric acid sodium is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid sodium is a biomarker of mustard airway diseases (MADs) and uric acid stone .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-17400
CAS No.: 17902-23-7
Synonyms: FT 207; NSC 148958
Research Areas:  

Cancer

Tegafur (FT 207; NSC 148958) is a chemotherapeutic 5-FU proagent used in the treatment of cancers; is a component of tegafur-uracil.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-14798
CAS No.: 31645-39-3
Purity:  99.11%
Synonyms: Isophosphoramide mustard; IPM; ZIO-201
Research Areas:  

Cancer

Palifosfamide is a novel DNA alkylator and the active metabolite of ifosfamide, with antitumor activity.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W127705
CAS No.: 4213-45-0
Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-114577
CAS No.: 1070409-31-2
Synonyms: Isophosphoramide mustard tromethamine; IPM tromethamine; ZIO-201 tromethamine
Research Areas:  

Cancer

Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W010820
CAS No.: 21931-53-3
Synonyms: UDP sodium salt
Uridine-5'-diphosphate (UDP) sodium salt is an important nucleotide made of uracil, ribose, and a pyrophosphate group. Uridine-5'-diphosphate sodium salt is a potent, selective human P2Y6 receptor native agonist (EC50 = 300 nM; pEC50 = 6.52). Uridine-5'-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W010832
CAS No.: 27821-45-0
Synonyms: UDP disodium salt
Uridine-5'-diphosphate (UDP) disodium salt is an important nucleotide made of uracil, ribose, and a pyrophosphate group. Uridine-5'-diphosphate disodium salt is a potent, selective human P2Y6 receptor native agonist (EC50 = 300 nM; pEC50 = 6.52). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W012926
CAS No.: 504-07-4
Synonyms: 5,6-DihydroUracil
Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N6652
CAS No.: 3083-77-0
Synonyms: Uracil 1-β-D-arabinofuranoside
1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has demonstrated a diverse bioactivity profile including anti-inflammatory activity, analgesic and vasodilation properties . 1-beta-D-Arabinofuranosyluracil reduces a proliferation of mouse lymphoma cells .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-141567A
Purity:  ≥98.0%
Synonyms: Pseudo-UTP trisodium solution (100 mM)
Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate trisodium solution (100 mM) enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate trisodium solution (100 mM) can be used for the research of vaccinia virus infection .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-I0960S4
CAS No.: 24897-52-7
Uracil-d2 is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .
loading...
    loading...