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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
VRAC
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "VRAC" in MCE Product Catalog:
11
11 Publications Verification
Target:
Research Areas:
DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK, and inhibits TRESK, TASK1 and TASK3 (IC50s: 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM. DCPIB is a useful tool for investigating structure-function studies of K2P channels .
6
6 Cited Publications
Synonyms: Endovion; NS3728
Target:
Research Areas:
Endovion is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor .
1
Category:
Neurological Disease Plants Pueraria lobata (Willd.) Ohwi var. montana (Lour.)van der Maesen Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Cancer Isoflavones
Target:
Cat. No.: HY-105917R
CAS No.: 265646-85-3
Synonyms: Endovion (Standard); NS3728 (Standard)
Target:
Research Areas:
Emidurdar (Standard) is the analytical standard of Emidurdar (HY-105917). This product is intended for research and analytical applications. Endovion is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor .
Cat. No.: HY-103371R
CAS No.: 82749-70-0
Research Areas:
DCPIB (Standard) is the analytical standard of DCPIB (HY-103371). This product is intended for research and analytical applications. DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK, and inhibits TRESK, TASK1 and TASK3 (IC50s: 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM. DCPIB is a useful tool for investigating structure-function studies of K2P channels .
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Protocols
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