Search Result
Results for "
X-rays
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-N0305
-
|
5-ALA hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride
|
Reactive Oxygen Species (ROS)
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) hydrochloride is an orally active heme precursor. 5-Aminolevulinic acid hydrochloride promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid hydrochloride enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid hydrochloride selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid hydrochloride can be applied to the research of septic shock, melanoma, and cancer radiotherapy .
|
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- HY-B0594
-
Iohexol
5 Publications Verification
|
Autophagy
Mitophagy
|
Cancer
|
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Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .
|
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- HY-W000450
-
|
5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid
|
Reactive Oxygen Species (ROS)
|
Cardiovascular Disease
Cancer
|
|
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) is an orally active heme precursor. 5-Aminolevulinic acid promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid can be applied to the research of septic shock, melanoma, and cancer radiotherapy .
|
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- HY-B1410
-
|
MP-328
|
Biochemical Assay Reagents
|
Others
Cancer
|
|
Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal .
|
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- HY-B1292
-
-
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- HY-B0684
-
|
B-15000; SQ-13396
|
Biochemical Assay Reagents
|
Cancer
|
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Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
|
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- HY-113314
-
|
|
Endogenous Metabolite
|
Cancer
|
|
AFMK, antioxidant metabolite of Melatonin, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. AFMK is a poorer scavenger. The pKa of AFMK at physiological pH is 8.7. Antioxidant capacity . AFMK improves the anti-tumor effect of Gemcitabine in PANC-1 cells through the modulation of apoptotic pathway .
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- HY-123622
-
|
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Biochemical Assay Reagents
|
Others
|
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CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .
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- HY-150137
-
|
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Biochemical Assay Reagents
|
Others
|
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Iomeprol is a nonionic X-ray contrast agent with low osmotic pressure, stable chemical properties, and can withstand high temperature sterilization. Iomeprol can be widely used in vascular, body cavity, and gastrointestinal angiography examinations .
|
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- HY-109513
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Ioxilan
1 Publications Verification
|
Biochemical Assay Reagents
|
Others
|
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Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs .
|
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- HY-125695
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- HY-B0594R
-
|
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Reference Standards
Autophagy
Mitophagy
|
Cancer
|
|
Iohexol (Standard) is the analytical standard of Iohexol. This product is intended for research and analytical applications. Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .
|
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- HY-W076166C
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- HY-W130190
-
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Biochemical Assay Reagents
|
Others
|
|
Iomeprol hydrolysate-2 (compound A) is iomeprol hydrolyzate, a key intermediate in the production of Iodixanol (HY-B1426) and Iohexol (HY-B0594) X-ray contrast agents .
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- HY-107943
-
|
NSC 107434 sodium
|
Biochemical Assay Reagents
|
Others
|
|
Tyropanoate (NSC 107434) sodium is an orally active contrast agent for the gallbladder. Tyropanoate sodium is absorbed through the intestines and secreted by the liver into the bile. Tyropanoate sodium then concentrates in the gallbladder to form an image that is not transparent to X-rays, enabling visualization of the gallbladder .
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- HY-121125
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|
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Others
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Others
|
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Aucubigenin, the aglycone of the iridoid glycoside aucubin, has been characterized through X-ray diffraction analysis. Its crystal structure reveals monoclinic symmetry with specific conformations adopted by its cyclopentane and pyran rings. The study also determined the absolute configurations of both aucubin and aucubigenin. Significant O-H O hydrogen bonding interactions were observed in the crystal lattices of both compounds, highlighting their structural stability and potential for intermolecular interactions .
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- HY-176217
-
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Biochemical Assay Reagents
DNA/RNA Synthesis
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Cancer
|
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dA-NHbenzylOCF3 is a DNA-targeted radiosensitizer that enhances the sensitivity of tumor cells to X-rays through the dissociative electron attachment (DEA) mechanism. dA-NHbenzylOCF3 has low toxicity to normal cells and is mainly localized in the cytoplasm and nucleus after entering the cell. dA-NHbenzylOCF3 exerts radiosensitization effects by inducing cell cycle arrest in the radiosensitive G2/M phase. dA-NHbenzylOCF3 can be used for radiosensitization studies of malignant tumors such as prostate cancer and breast cancer .
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- HY-125695S
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- HY-W799437
-
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Biochemical Assay Reagents
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Others
|
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Ioversol hydrolysate-1 is a hydrolyzate of Ioversol (HY-B1410), a non-ionic iodinated contrast agent (CM) used in CT scans or X-rays in animal experiments .
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- HY-B1292R
-
|
Adipiodone (Standard)
|
Reference Standards
|
Others
|
|
Iodipamide (Standard) is the analytical standard of Iodipamide. This product is intended for research and analytical applications. Iodipamide is an iodine-based contrast agent, mainly used for X-ray imaging, particularly for gallbladder and bile duct imaging [1] .
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- HY-117980
-
|
AB 132
|
DNA/RNA Synthesis
|
Cancer
|
|
Meturedepa (AB 132) functions as a radiation sensitizer, enhancing the biological effects of radiation. When combined with suboptimal doses of X-ray radiation, this combined therapy achieves better outcomes in terms of tumor shrinkage compared to Meturedepa used alone. Meturedepa is applicable in the research of bronchogenic carcinoma .
|
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- HY-125473
-
|
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Endogenous Metabolite
|
Infection
|
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IDX375 is a novel non-nucleoside inhibitor with selective inhibitory activity against HCV NS5B. IDX375 has good selectivity for genotypes 1a and 1b. The structure and binding site of IDX375 were confirmed by X-ray cocrystal studies .
|
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- HY-B0684R
-
|
B-15000 (Standard); SQ-13396 (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Cancer
|
|
Iopamidol (Standard) is the analytical standard of Iopamidol. This product is intended for research and analytical applications. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
|
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- HY-W153917
-
|
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Biochemical Assay Reagents
|
|
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Diatrizoic acid EP impurity A is an organic compound with potential effects on biological systems and specific pharmacological activities. Diatrizoic acid EP impurity A can be used as a contrast agent in imaging examinations to enhance the clarity of images such as X-rays and CT scans. Diatrizoic acid EP impurity A has also been studied for the separation and analysis of compounds.
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- HY-107962
-
|
Renovue 65
|
Biochemical Assay Reagents
|
Others
|
|
Iodamide meglumine (Renovue 65) is a type of trityl ion contrast agent. Iodamide meglumine can block X-rays and is used in examinations such as cholangiography and cholecystography to display the gallbladder and bile ducts. Iodamide meglumine has the property of renal tubular active secretion. Iodamide meglumine can be used for intravenous urography .
|
-
-
- HY-B1410R
-
|
MP-328 (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Others
Cancer
|
|
Ioversol (Standard) is the analytical standard of Ioversol. This product is intended for research and analytical applications. Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal [4].
|
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- HY-B0684S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Iopamidol-d8 (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
|
-
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- HY-W130190R
-
|
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Biochemical Assay Reagents
Reference Standards
|
Others
|
|
Iomeprol hydrolysate-1 (Standard) is the analytical standard of Iomeprol hydrolysate-1. This product is intended for research and analytical applications. Iomeprol hydrolysate-2 (compound A) is iomeprol hydrolyzate, a key intermediate in the production of Iodixanol (HY-B1426) and Iohexol (HY-B0594) X-ray contrast agents .
|
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- HY-111333
-
|
Dioxapyrrolomycin; LL-F42248α; AL-R2081
|
Bacterial
|
Infection
|
|
Pyrroxamycin is a novel antibiotic produced by Streptomyces, whose chemical structure was determined by chemical properties and X-ray crystallography and 13C NMR spectroscopy analysis. It is active against Gram-positive bacteria and dermatophytes. In this paper, the authors discuss the taxonomy, fermentation, isolation, physicochemical properties, chemical structure, and biological activity of the strain producing Pyrroxamycin.
|
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- HY-106586A
-
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P-286 sodium
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
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Ioxaglate sodium (P-286 sodium) is an ionic, dimeric diagnostic contrast agent whose activity is mainly reflected in its ability to provide sufficient X-ray absorption to enhance visualization of blood vessels and other structures during imaging. Ioxaglate sodium is used to study the anatomical structure and functional status of cardiac vessels, especially in the diagnosis of coronary artery disease .
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- HY-P2138
-
|
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HIV Protease
|
Others
|
|
U-85548E is an HIV protease inhibitor with nanomolar affinity for HIV-1 aspartic protease. By studying its structure-activity relationship, a potent nanomolar inhibitor with inhibitory effects on both HIV-1 and HIV-2 proteases was designed, and its binding mode was studied by X-ray crystallography and molecular modeling.
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- HY-120631A
-
|
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Dipeptidyl Peptidase
|
Others
|
|
BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis.
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- HY-B0684S1
-
|
B-15000-d3; SQ-13396-d3
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Cancer
|
|
Iopamidol-d3 (B-15000-d3; SQ-13396-d3) is the deuterium labeled Iopamidol (HY-B0684). Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
|
-
-
- HY-109513R
-
|
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
|
Ioxilan (Standard) is the analytical standard of Ioxilan. This product is intended for research and analytical applications. Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs .
|
-
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- HY-W250179
-
|
Polyoxyethylene (6) cetyl ether
|
Biochemical Assay Reagents
|
Others
|
|
Hexaethylene glycol monohexadecyl ether, is a nonionic surfactant belonging to the polyethylene glycol (PEG) ether family. It has a hydrophilic head and a lipophilic tail, which makes it suitable for a wide range of applications. Specifically, Hexaethylene glycol monohexadecyl ether is commonly used in membrane protein research, for solubilization and stabilization of proteins, and for structural analysis techniques such as X-ray crystallography and electron microscopy. Additionally, Hexaethylene glycol monohexadecyl ether is used in a variety of other industrial and research applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Its unique properties make it ideal for facilitating interactions between molecules with different physicochemical properties.
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- HY-106317
-
|
Glutathione isopropyl ester; YM 737
|
Drug Derivative
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Glutathione monoisopropyl ester (Glutathione isopropyl ester) is an ester derivative of glutathione. Glutathione monoisopropyl ester can increase glutathione concentrations in tissues such as the liver, lungs, heart, and brain of mice, exerting a dose-dependent protective effect against liver injury. Glutathione monoisopropyl ester effectively inhibits ultraviolet-induced lipid peroxidation, inflammatory responses, and tumorigenesis in the skin of hairless mice by maintaining epidermal glutathione levels. Glutathione monoisopropyl ester also inhibits the progression of X-ray-induced cataracts in rats .
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- HY-B1292B
-
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Adipiodone meglumine
|
Biochemical Assay Reagents
|
Others
|
|
Iodipamide (Adipiodone) meglumine is an iodine-based contrast agent, mainly used for X-ray imaging, particularly for gallbladder and bile duct imaging.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-123622
-
|
|
Biochemical Assay Reagents
|
|
CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .
|
-
- HY-W076166C
-
-
- HY-W250179
-
|
Polyoxyethylene (6) cetyl ether
|
Biochemical Assay Reagents
|
|
Hexaethylene glycol monohexadecyl ether, is a nonionic surfactant belonging to the polyethylene glycol (PEG) ether family. It has a hydrophilic head and a lipophilic tail, which makes it suitable for a wide range of applications. Specifically, Hexaethylene glycol monohexadecyl ether is commonly used in membrane protein research, for solubilization and stabilization of proteins, and for structural analysis techniques such as X-ray crystallography and electron microscopy. Additionally, Hexaethylene glycol monohexadecyl ether is used in a variety of other industrial and research applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Its unique properties make it ideal for facilitating interactions between molecules with different physicochemical properties.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2138
-
|
|
HIV Protease
|
Others
|
|
U-85548E is an HIV protease inhibitor with nanomolar affinity for HIV-1 aspartic protease. By studying its structure-activity relationship, a potent nanomolar inhibitor with inhibitory effects on both HIV-1 and HIV-2 proteases was designed, and its binding mode was studied by X-ray crystallography and molecular modeling.
|
-
- HY-K2006
-
|
|
|
Sensitive ECL Kit enables low picogram detection of antigen by oxidizing luminol in the presence of HRP and peroxide. This reaction produces a prolonged chemiluminescence which can be visualized on X-ray film or digital imaging systems. The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
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- HY-K2005
-
|
|
|
High Sensitivity ECL Kit enables low picogram detection of antigen by oxidizing luminol in the presence of HRP and peroxide. This reaction produces a prolonged chemiluminescence which can be visualized on X-ray film or digital imaging systems. The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N0305
-
|
5-ALA hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride
|
Structural Classification
Classification of Application Fields
Ketones, Aldehydes, Acids
Endogenous metabolite
Disease Research Fields
Cancer
|
Reactive Oxygen Species (ROS)
|
|
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) hydrochloride is an orally active heme precursor. 5-Aminolevulinic acid hydrochloride promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid hydrochloride enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid hydrochloride selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid hydrochloride can be applied to the research of septic shock, melanoma, and cancer radiotherapy .
|
-
-
- HY-W000450
-
-
-
- HY-113314
-
-
-
- HY-121125
-
-
-
- HY-111333
-
|
Dioxapyrrolomycin; LL-F42248α; AL-R2081
|
Microorganisms
Antibiotics
Source Classification
|
Bacterial
|
|
Pyrroxamycin is a novel antibiotic produced by Streptomyces, whose chemical structure was determined by chemical properties and X-ray crystallography and 13C NMR spectroscopy analysis. It is active against Gram-positive bacteria and dermatophytes. In this paper, the authors discuss the taxonomy, fermentation, isolation, physicochemical properties, chemical structure, and biological activity of the strain producing Pyrroxamycin.
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-125695S
-
|
|
|
Ioxitalamic acid-d4 is the deuterium labeled Loxitalamic acid (HY-125695). Ioxitalamic acid is a water-soluble, nephrophilic, highly permeable X-ray iodinated contrast media .
|
-
-
- HY-B0684S
-
|
|
|
Iopamidol-d8 (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
|
-
-
- HY-B0684S1
-
|
|
|
Iopamidol-d3 (B-15000-d3; SQ-13396-d3) is the deuterium labeled Iopamidol (HY-B0684). Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .
|
-
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