Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
ZIP
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "ZIP" in MCE Product Catalog:
9
9 Publications Verification
Target:
Research Areas:
NVS-ZP7-4 is an inhibitor of the zinc transporter SLC39A7 (ZIP7) and indicates ER zinc levels. ZIP7 is an active molecular node in the Notch pathway and mediates ferroptosis. NVS-ZP7-4 induces ER stress and exerts a certain ferroptosis-inhibiting effect, reduces Erastin (HY-15763)-induced cell death .
2
2 Cited Publications
Cat. No.: HY-P1284
CAS No.: 863987-12-6
Target:
Research Areas:
2
2 Cited Publications
Target:
Research Areas:
(R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel agentgable node in the Notch pathway.
2
Cat. No.: HY-P99682
CAS No.: 1629760-28-6
Synonyms: hLIV22
Target:
Research Areas:
Research Areas:
ZIP 14-IN-1 (PPTD) is a selective and orally active ZIP14 inhibitor. ZIP 14-IN-1 inhibits ZIP14 while sparing ZIP8 (SLC39A8). ZIP 14-IN-1 efficiently blocks ZIP14-mediated uptake of multiple divalent metals (zinc, iron, manganese and cadmium). ZIP 14-IN-1 binds to a pocket formed at the dimer interface of ZIP14, obstructing the metal transport pathway. ZIP 14-IN-1 effectively reverses the consequent elevation of reactive oxygen species (ROS) and lipid peroxidation, attenuating metal-induced cytotoxicity. ZIP 14-IN-1 can be uses for cancer cachexia research .
Cat. No.: HY-RS03529
Target:
Research Areas:
DAPK3 Human Pre-designed siRNA Set A contains three designed siRNAs for DAPK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P1391
CAS No.: 908012-18-0
Cat. No.: HY-RS16066
Target:
Research Areas:
ZGPAT Human Pre-designed siRNA Set A contains three designed siRNAs for ZGPAT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23805
Target:
Research Areas:
Sqstm1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sqstm1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P78569
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; LIV-1; ZIP6; Zinc transporter ZIP6; ZIP-6
Species:
Source:
Cat. No.: HY-P78616
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; LIV-1; ZIP6; Zinc transporter ZIP6; ZIP-6
Species:
Source:
Cat. No.: HY-P700463
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; LIV-1; ZIP6; Zinc transporter ZIP6; ZIP-6
Species:
Source:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
