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NVS-ZP7-4 

Cat. No.: HY-114395
Handling Instructions

NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel druggable node in the Notch pathway.

For research use only. We do not sell to patients.

NVS-ZP7-4 Chemical Structure

NVS-ZP7-4 Chemical Structure

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel druggable node in the Notch pathway.

IC50 & Target

ZIP7[1].

In Vitro

NVS-ZP7-4 increases ER zinc levels, suggesting functional modulation of ZIP7[1].

References
Molecular Weight

501.62

Formula

C₂₈H₂₈FN₅OS

SMILES

O=C(NC12CCN(C[[email protected]@H](NC3=NC4=CC=C(F)C=C4S3)CC5=CC=CC=C5)CC2)NC6=C1C=CC=C6

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
NVS-ZP7-4
Cat. No.:
HY-114395
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NVS-ZP7-4

Cat. No.: HY-114395