2349367-89-9
Chemical Structure
NVS-ZP7-4
- CAS No.: 2349367-89-9
- Formula:C28H28FN5OS
- Molecular Weight:501.62
IUPAC Name: (S)-1-(2-((6-fluorobenzo[d]thiazol-2-yl)amino)-3-phenylpropyl)-1'H-spiro[piperidine-4,4'-quinazolin]-2'(3'H)-one
InChIKey: FZOFDZMKSAUTHT-NRFANRHFSA-N
SMILES: O=C(NC12CCN(C[C@@H](NC3=NC4=CC=C(F)C=C4S3)CC5=CC=CC=C5)CC2)NC6=C1C=CC=C6
Biological Activity: NVS-ZP7-4 is an inhibitor of the zinc transporter SLC39A7 (ZIP7) and indicates ER zinc levels. ZIP7 is an active molecular node in the Notch pathway and mediates ferroptosis. NVS-ZP7-4 induces ER stress and exerts a certain ferroptosis-inhibiting effect, reduces Erastin (HY-15763)-induced cell death[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NVS-ZP7-4 | 98.85% | NVS-ZP7-4 is an inhibitor of the zinc transporter SLC39A7 (ZIP7) and indicates ER zinc levels. ZIP7 is an active molecular node in the Notch pathway and mediates ferroptosis. NVS-ZP7-4 induces ER stress and exerts a certain ferroptosis-inhibiting effect, reduces Erastin (HY-15763)-induced cell death. | ||||||||||||||||||||
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Keywords
