Search Result
Results for "
aldehyde groups
" in MedChemExpress (MCE) Product Catalog:
67
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-128692
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Fluorescent Dye
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Neurological Disease
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Luc Yellow CH dilithium is a high-intensity fluorescent probe containing free hydrazyl groups. Luc Yellow CH can react with fatty aldehydes at room temperature. Luc Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Luc Yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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- HY-W127715
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Fluorescent Dye
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Others
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Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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- HY-147168
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Biochemical Assay Reagents
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Others
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Biocytin hydrazide is a long-chain biotin-containing hydrazide, serving as a biotin-derived active coupling reagent, selective labeling agent and biotinylating reagent. Biocytin hydrazide targets aldehyde, carboxyl, amino and guanidino groups to biotinylate glycoconjugates, K99 lectin, peptides and proteins through its hydrazide moiety, and achieves nonradioactive detection of sialic acid- and galactose-containing glycoconjugates via the avidin–biotin system .
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- HY-W590569
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Biochemical Assay Reagents
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Others
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Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.
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- HY-D1336
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Fluorescent Dye
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FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.
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- HY-W018829
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Undecylenic aldehyde
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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10-Undecenal consists of an 11-carbon chain with a double bond between the 9th and 10th carbon atoms and an aldehyde group attached to the 1st carbon atom. This compound has a pungent or fatty smell and is commonly used as a flavoring commodity in foods such as bakery, confectionary and beverages.
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- HY-W039943
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Molecular Glues
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Cancer
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Acetyl-cyclosporin A aldehyde is an acetylated Cyclosporin A (HY-B0579) derivative with a reducing aldehyde group. Cyclosporin A is a potent calmodulin inhibitor and cyclophilin binder that can target the nuclear translocation of NF-AT and cause mitochondrial damage.
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- HY-W017425
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Phenylhydrazine acetate
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Biochemical Assay Reagents
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Others
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N'-Phenylacetohydrazide consists of a phenyl group attached to the acetylhydrazide functional group via a hydrazine bond. This compound is commonly used as a reagent in organic chemistry for the determination of carbonyl compounds such as aldehydes and ketones.
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- HY-W012971
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Biochemical Assay Reagents
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Others
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5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-42773
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1-Boc-1,8-diaminooctane
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PROTAC Linkers
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Cancer
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tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W190915
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Biochemical Assay Reagents
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Others
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4,7,10,13,16–Pentaoxanonadecane-1,19-diamine is a PEG based linker with two terminal amine groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-W142618
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Biochemical Assay Reagents
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Others
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D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.
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- HY-W105744
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PROTAC Linkers
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Cancer
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10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
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- HY-138518
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PROTAC Linkers
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Cancer
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Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-176509A
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Liposome
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Others
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DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .
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- HY-W105727
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PROTAC Linkers
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Cancer
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9-Aminononanoic acid can be used as a PROTAC linker and other conjugation in the synthesis of PROTACs. 9-Aminononanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
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- HY-172379A
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Biochemical Assay Reagents
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Others
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Alginate aldehyde, 35% aldehyde content is an anionic polysaccharide widely used in pharmaceutical and biomedical applications. Aldehyde-functionalized Alginate aldehyde can be used to prepare hydrogels by reacting with amine groups .
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- HY-N15067
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Biochemical Assay Reagents
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Others
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7-O-methylluteone is a hydroxyisoflavone that is luteone in which the hydroxy group at position 7 is replaced by a methoxy group. 7-O-Methylluteone has a role as an EC (aldehyde reductase) inhibitor and a metabolite .
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- HY-W998707
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Fluorescent Dye
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Others
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TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-42222
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Biochemical Assay Reagents
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Others
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N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-176509C
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Liposome
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Others
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DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .
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- HY-176509
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Liposome
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Others
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DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .
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- HY-D2502
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Fluorescent Dye
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Others
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Cy7 hydrazide is a Cy7 (HY-D0825) dye derivative with hydrazine functionality. The hydrazide group of Cy7 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
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- HY-176846
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Biochemical Assay Reagents
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Others
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HIPS probe-1 (Compound 1) is a click chemistry reagent containing a alkyne group. HIPS probe-1 can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. HIPS probe-1 can be used as a chemical probe to specifically recognize and label aldehyde functional groups in DNA, especially abasic sites (AP sites) for DNA damage research .
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- HY-141147
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Drug-Linker Conjugates for ADC
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Cancer
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7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
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- HY-136054
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ADC Linker
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Cancer
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N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-135977
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ADC Linker
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Cancer
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DBCO-SS-aldehyde is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-SS-aldehyde is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-W588728
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Biochemical Assay Reagents
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Others
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DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
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- HY-W101722
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PROTAC Linkers
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Cancer
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tert-Butyl (9-aminononyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W190918
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Biochemical Assay Reagents
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Others
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endo-BCN-PEG4-amine is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-W1048547J
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HOOC-PEG40000-Amine
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PROTAC Linkers
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Others
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HOOC-PEG40000-NH2 (HOOC-PEG40000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
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- HY-174948
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NHS-PEG1000-aldehyde
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Biochemical Assay Reagents
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Others
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NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-174948C
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NHS-PEG5000-aldehyde
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Biochemical Assay Reagents
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Others
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NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-172379
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Biochemical Assay Reagents
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Others
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Alginate aldehyde, 20% aldehyde content is an anionic polysaccharide widely used in pharmaceutical and biomedical applications. Aldehyde-functionalized Alginate aldehyde can be used to prepare hydrogels by reacting with amine groups .
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- HY-118118
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Fungal
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Infection
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Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite with strong antifungal activity. Phlebiakauranol aldehyde exhibits significant antibacterial and cytotoxic activities against a variety of plant pathogens. The aldehyde group and high number of hydroxyl groups of Phlebiakauranol aldehyde are considered to be the main reasons for its biological activity. The two acetic acid derivatives of Phlebiakauranol aldehyde only exhibit very weak antifungal and antibacterial activities and moderate cytotoxic activity .
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- HY-136074
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ADC Linker
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Cancer
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Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-136077
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ADC Linker
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Cancer
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(S)-TCO-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . (S)-TCO-PEG3-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-136076
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ADC Linker
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Cancer
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TCO-PEG3-CH2-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-CH2-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-W591969
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Biochemical Assay Reagents
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Others
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Benzyl (6-oxohexyl)carbamate is a linker containing an aldehyde group and a benzyl (Cbz) protecting group. The aldehyde can react with hydrazine or hydrazide to form a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
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- HY-W591965
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Biochemical Assay Reagents
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Others
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t-Boc-Aminooxy-pentane-amine is a linker containing an aminooxy group and a primary amine. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-138064
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Biochemical Assay Reagents
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Others
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4-APC hydrobromide is a highly sensitive and selective derivatization agent for aldehydes. 4-APC hydrobromide possesses an aniline moiety for a fast selective reaction with aliphatic aldehydes as well as a quaternary ammonium group for improved MS sensitivity. 4-APC hydrobromide allows highly sensitive and selective MS detection of aldehydes .
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- HY-136140
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PROTAC Linkers
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Cancer
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Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Aldehyde-benzyl-PEG5-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-133465
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PROTAC Linkers
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Cancer
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Tetrazine-Ph-PEG4-Ph-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG4-Ph-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-W800649
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Biochemical Assay Reagents
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Others
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Aminooxy-PEG2-amine hydrochloride (compound L3) is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term .
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- HY-174930
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Biochemical Assay Reagents
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Others
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Amino-PEG41-alcohol is a PEG derivative consisting of an alcohol, PEG unit and an amino group. The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds .
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- HY-W588736
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Biochemical Assay Reagents
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Others
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DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
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- HY-132263
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Fluorescent Dye
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Others
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FAM hydrazide, 5-isomer is a Fluorescein dye linker containing a hydrazide group. Fluorescein is a universal dye. Hydrazide moieties react with aldehydes to form semi-permanent hydrazone bonds.
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- HY-169763
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IRE1
Apoptosis
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Cancer
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D-F07 is a prodrug with an aldehyde shielding group and an IRE-1 inhibitor that induces Apoptosis. D-F07 has antitumor activity .
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- HY-W800657
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Biochemical Assay Reagents
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Others
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Azido-PEG1-hydrazide hydrochloride is a bifunctional PEG linker containing an azide group and a hydrazide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds.
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- HY-W800654
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Biochemical Assay Reagents
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Others
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Mal-PEG5-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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- HY-42213
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Biochemical Assay Reagents
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Others
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N1,N4-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-174916
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Biochemical Assay Reagents
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Others
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Amine-PEG1-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 1 PEG unit, and an amino group (Amine). Desthiobiotin is a biotin analog that has a weak but reversible binding ability to streptavidin or avidin. The amino group is able to react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
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- HY-176509D
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Liposome
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Others
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DSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery .
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- HY-176509B
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Liposome
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Others
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DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .
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- HY-176509H
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Liposome
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Others
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DSPE-PEG40000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG40000-CHO can be used for drug delivery .
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- HY-172284
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Fluorescent Dye
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Others
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6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
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- HY-23629
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PROTAC Linkers
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Cancer
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16-Aminohexadecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 16-Aminohexadecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
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- HY-W401143
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PROTAC Linkers
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Cancer
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15-Aminopentadecanoic Acid can be used as a PROTAC linker in the synthesis of PROTACs. 15-Aminopentadecanoic Acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
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- HY-W1048574I
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OHC-PEG3400-carboxyl
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Biochemical Assay Reagents
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Others
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OHC-PEG3400-COOH (OHC-PEG3400-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG3400-COOH can be used for drug delivery .
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- HY-W1048574E
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OHC-PEG20000-carboxyl
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Biochemical Assay Reagents
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Others
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OHC-PEG20000-COOH (OHC-PEG20000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG20000-COOH can be used for drug delivery .
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- HY-W190905
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Biochemical Assay Reagents
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Others
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N4, N9-di-Boc-spermine is a spermine linker containing two a Boc-protected amino groups and two amine groups. The Boc groups can be deprotected under mild acidic conditions to form the free amine. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Spermidine is a polyamine that modulates various cellular activities like cellular development and differentiation, stability of DNA, and apoptosis.
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- HY-W348348
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Biochemical Assay Reagents
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Others
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CbzNH-PEG3-CH2CH2NH2 is a PEG linker containing an amine group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
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- HY-W131541
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PROTAC Linkers
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Cancer
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tert-Butyl (11-aminoundecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. tert-Butyl (11-aminoundecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-174948B
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NHS-PEG3400-aldehyde
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Biochemical Assay Reagents
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Others
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NHS-PEG3400-CHO (NHS-PEG3400-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-174948A
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NHS-PEG2000-aldehyde
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Biochemical Assay Reagents
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Others
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NHS-PEG2000-CHO (NHS-PEG2000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-W143230
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4-Benzyloxybutanal
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Biochemical Assay Reagents
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Others
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4-(Benzyloxy)butanal (4-Benzyloxybutanal) is a linker with an acid labile, benzyl protecting group and a reactive primary aldehyde. The primary aldehyde can react with hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates).
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- HY-W590588
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Biochemical Assay Reagents
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Others
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Diethyl acetal-PEG4-amine is a PEG reagent containing an amino (NH2) group and a terminal diethyl acetal protecting group, which can be deprotected to form the free aldehyde. NH2 group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
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- HY-W840196
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Biochemical Assay Reagents
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Others
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Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
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- HY-174932
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Biochemical Assay Reagents
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Others
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Amino-PEG18-t-butyl ester is a PEG derivative consisting of t-butyl ester, PEG unit and an amino group (Amine). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
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- HY-E71098
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Biochemical Assay Reagents
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Metabolic Disease
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(R)-Dehydropantoate dehydrogenase (EC 1.2.1.33) belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor.
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- HY-W153502
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Biochemical Assay Reagents
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Others
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MeNH-PEG2-OH is a PEG linker containing a hydroxyl group with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc.
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- HY-W479025
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Biochemical Assay Reagents
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Others
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Fmoc-DODA hydrochloride is a linker with an Fmoc-protected amine and a terminal amine group. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-W1123946H
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Biochemical Assay Reagents
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Others
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8-Arm-PEG10000-CHO is a polyethylene glycol derivative with multiple active aldehyde groups, which can be used to construct drug delivery carriers .
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- HY-W1123946A
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Biochemical Assay Reagents
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Others
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8-Arm-PEG40000-CHO is a polyethylene glycol derivative with multiple active aldehyde groups, which can be used to construct drug delivery carriers .
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- HY-W1123946
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Biochemical Assay Reagents
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Others
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8-Arm-PEG20000-CHO is a polyethylene glycol derivative with multiple active aldehyde groups, which can be used to construct drug delivery carriers .
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- HY-W591379
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Biochemical Assay Reagents
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Others
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Amino-PEG19-amine is a PEG linker containing two amine functional groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
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- HY-W190922
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Biochemical Assay Reagents
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Others
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Mal-PEG4-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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- HY-W793100
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Biochemical Assay Reagents
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Others
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Endo-BCN-PEG2-Biotin is a PEG linker containing a BCN group and a terminal carboxylic acid. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-W154175
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Biochemical Assay Reagents
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Others
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Boc-DODA is a linker containing a Boc-protected amino group and a terminal amine. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-WAA0302
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Biochemical Assay Reagents
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Others
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1,4-Bis-Boc-1,4,7-triazaheptane is a PEG derivative containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W1113139
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Biochemical Assay Reagents
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Others
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H2N-PEG4-C3-OH is a PEG linker with a terminal amino group that can react with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. Hydroxyl group can react with a variety of functional groups. PEG spacer improves the compound's aqueous solubility.
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- HY-176509E
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Liposome
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Others
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DSPE-PEG20000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG20000-CHO can be used for drug delivery .
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- HY-W800650
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Biochemical Assay Reagents
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Others
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Aminooxy-PEG1-amine is a chemical reagent containing an aminooxy group and a primary amine. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive withactivated NHS esters, or carboxylic acid in the presence of coupling reagent EDC. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term.
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- HY-W092344
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Biochemical Assay Reagents
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Others
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1,5-Bis-Boc-1,5,9-triazanonane is a linker containing two Boc-protected amino groups and a terminal amine. The Boc groups can be deprotected under mild acidic conditions to form the free amines. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-W1048574J
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OHC-PEG40000-carboxyl
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Biochemical Assay Reagents
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Others
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OHC-PEG40000-COOH (OHC-PEG40000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG40000-COOH can be used for drug delivery .
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- HY-W1048574H
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OHC-PEG1000-carboxyl
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Biochemical Assay Reagents
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Others
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OHC-PEG1000-COOH (OHC-PEG1000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG1000-COOH can be used for drug delivery .
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- HY-W1048574A
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OHC-PEG2000-carboxyl
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Biochemical Assay Reagents
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Others
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OHC-PEG2000-COOH (OHC-PEG2000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG2000-COOH can be used for drug delivery .
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- HY-W1048574D
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OHC-PEG10000-carboxyl
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Biochemical Assay Reagents
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Others
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OHC-PEG10000-COOH (OHC-PEG10000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG10000-COOH can be used for drug delivery .
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- HY-W1048574C
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OHC-PEG5000-carboxyl
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Biochemical Assay Reagents
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Others
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OHC-PEG5000-COOH (OHC-PEG5000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG5000-COOH can be used for drug delivery .
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- HY-W1048547A
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HOOC-PEG2000-Amine
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Biochemical Assay Reagents
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Others
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HOOC-PEG2000-NH2 (HOOC-PEG2000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
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- HY-W1048547H
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HOOC-PEG1000-Amine
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Biochemical Assay Reagents
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Others
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HOOC-PEG1000-NH2 (HOOC-PEG1000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
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- HY-W1048547E
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HOOC-PEG20000-Amine
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Biochemical Assay Reagents
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Others
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HOOC-PEG20000-NH2 (HOOC-PEG20000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
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- HY-W1048547I
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HOOC-PEG3400-Amine
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Biochemical Assay Reagents
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Others
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HOOC-PEG3400-NH2 (HOOC-PEG3400-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
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- HY-W1048547C
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HOOC-PEG5000-Amine
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Biochemical Assay Reagents
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Others
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HOOC-PEG5000-NH2 (HOOC-PEG5000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
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- HY-W1048547D
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HOOC-PEG10000-Amine
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Biochemical Assay Reagents
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Others
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HOOC-PEG10000-NH2 (HOOC-PEG10000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
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- HY-183171
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Biochemical Assay Reagents
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Others
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DSG-PEG1000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG1000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-183171D
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Biochemical Assay Reagents
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Others
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DSG-PEG10000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG10000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-183171B
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Biochemical Assay Reagents
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Others
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DSG-PEG5000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG5000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-183171C
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Biochemical Assay Reagents
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Others
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DSG-PEG3400-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG3400-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-183171A
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Biochemical Assay Reagents
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Others
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DSG-PEG2000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-183398B
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Biochemical Assay Reagents
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Others
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DMG-PEG3400-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG3400-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-183398A
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Biochemical Assay Reagents
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Others
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DMG-PEG2000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-183398D
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Biochemical Assay Reagents
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Others
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DMG-PEG10000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG10000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-183398C
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Biochemical Assay Reagents
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Others
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DMG-PEG5000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG5000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-183398
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Biochemical Assay Reagents
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Others
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DMG-PEG1000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG1000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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- HY-W879032
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Biochemical Assay Reagents
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Others
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Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
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- HY-W047688
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1-Boc-1,10-diaminodecane
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PROTAC Linkers
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Cancer
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tert-Butyl (10-aminodecyl) carbamate (1-Boc-1,10-diaminodecane) is a synthetic intermediate that serves as a PROTAC linker in PROTAC synthesis and other conjugation applications. tert-Butyl (10-aminodecyl) carbamate is an alkane chain with a terminal amine and a Boc-protected amino group. The amine group can react with carboxylic acids, active NHS esters, carbonyl groups (ketones, aldehydes), etc. The Boc group can be deprotected under mild acidic conditions to form a free amine .
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- HY-P2743B
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Biochemical Assay Reagents
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Metabolic Disease
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Choline oxidase, Arthrobacter globiformis (EC 1.1.3.17) is an oxidoreductase that acts on the CH-OH group in a donor molecule and uses oxygen as an acceptor. The two substrates of Choline oxidase, Arthrobacter globiformis (EC 1.1.3.17) are choline and O2, and the two products are betaine aldehyde and H2O2.
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- HY-P2743A
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Biochemical Assay Reagents
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Metabolic Disease
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Choline oxidase, Alcaligenes sp. (EC 1.1.3.17) is an oxidoreductase that acts on the CH-OH group in a donor molecule and uses oxygen as an acceptor. The two substrates of Choline oxidase, Alcaligenes sp. (EC 1.1.3.17) are choline and O2, and the two products are betaine aldehyde and H2O2.
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- HY-141148
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Drug-Linker Conjugates for ADC
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Cancer
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7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Cbz-N-amido-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
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- HY-W879044
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Endo-BCN-PEG15-NH2
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Biochemical Assay Reagents
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Others
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Endo-BCN-PEG15-amine (Endo-BCN-PEG15-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
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- HY-D2388A
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Fluorescent Dye
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Others
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Sulfo Cy5.5-hydrazide sodium is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide sodium can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
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- HY-D2388
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Fluorescent Dye
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Others
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Sulfo Cy5.5-hydrazide is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
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- HY-W879025
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Endo-BCN-PEG8-NH2
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Biochemical Assay Reagents
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Others
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Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
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- HY-W879045
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Endo-BCN-PEG5-NH2
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Biochemical Assay Reagents
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Others
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Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
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- HY-P2756B
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Biochemical Assay Reagents
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Metabolic Disease
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Alcohol Oxidase, Pichia pastoris (EC 1.1.3.13) is a redox enzyme that acts on the CH-OH group in donor molecules and uses oxygen as an acceptor. The two substrates of Alcohol Oxidase, Pichia pastoris (EC 1.1.3.13) are primary alcohols and O2, while its two products are aldehydes and H2O2.
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- HY-P2756A
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Biochemical Assay Reagents
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Metabolic Disease
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Alcohol oxidase, Hansenula sp. (EC 1.1.3.13) is a redox enzyme that acts on the CH-OH group in donor molecules and uses oxygen as an acceptor. The two substrates of Alcohol Oxidase, Hansenula sp. (EC 1.1.3.13) are primary alcohols and O2, while its two products are aldehydes and H2O2.
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- HY-W1049075E
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Biochemical Assay Reagents
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Others
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mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
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- HY-W1049075H
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Biochemical Assay Reagents
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Others
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mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
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- HY-W1049075A
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Biochemical Assay Reagents
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Others
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mPEG5000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
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- HY-W1049075C
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Biochemical Assay Reagents
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Others
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mPEG20000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
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- HY-W1049075B
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Biochemical Assay Reagents
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Others
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mPEG10000-Pald is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
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- HY-W1049075D
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Biochemical Assay Reagents
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Others
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mPEG40000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
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- HY-W1049075
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Biochemical Assay Reagents
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Others
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mPEG1000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
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- HY-125372
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ABAO
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Biochemical Assay Reagents
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Others
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2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n
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- HY-W047710
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Biochemical Assay Reagents
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Others
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D-Galactal is a monosaccharide that belongs to the class of carbohydrates. It is an aldohexose, which means it has six carbon atoms and an aldehyde functional group. D-Galactal occurs naturally in certain foods such as dairy products, meats and fruits. It can also be synthesized by chemical or enzymatic processes. D-Galactal has various applications in the food industry, especially as a flavoring and sweetening agent. Additionally, it has potential research roles in metabolic disorders, cancer, and inflammation.
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- HY-E70385A
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Endogenous Metabolite
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Metabolic Disease
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Oxalate oxidase, B. subtilis (EC 1.2.3.4) is a redox enzyme that acts on the donor aldehyde or carbonyl group, using oxygen as the acceptor. Oxalate oxidase, B is involved in the metabolism of glyoxylate and dicarboxylic acids. Oxalate oxidase, B has two cofactors: FAD and manganese. Oxalate oxidase, B has three substrates: oxalic acid, O2, and H +, and two products: CO2 and H2O2.
|
-
- HY-116879
-
|
(2E)-4-Oxo-2-nonen-8-ynal; alkynyl-4-ONE
|
Exosomes
Others
|
Cancer
|
|
4-Oxo-2-Nonenal Alkyne ((2E)-4-Oxo-2-nonen-8-ynal; alkynyl-4-ONE) is a functionalized lipid electrophile that conjugated to the exosomes via the reaction of amino and aldehyde groups. 4-Oxo-2-Nonenal Alkyne can be used in tumor exosomes determination .
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-
- HY-155908
-
|
DSPE-PEG10000-NH2 ammonium
|
Liposome
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Others
|
|
DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
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-
- HY-W018829R
-
|
Undecylenic aldehyde (Standard)
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Biochemical Assay Reagents
Reference Standards
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Others
|
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10-Undecenal (Standard) is the analytical standard of 10-Undecenal (HY-W018829). This product is intended for research and analytical applications. 10-Undecenal consists of an 11-carbon chain with a double bond between the 9th and 10th carbon atoms and an aldehyde group attached to the 1st carbon atom. This compound has a pungent or fatty smell and is commonly used as a flavoring commodity in foods such as bakery, confectionary and beverages.
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-
- HY-E71129
-
|
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Biochemical Assay Reagents
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Others
|
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The reaction makes a six-membered ring by forming a bond between C-6 of the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde in the imine formed between the substrates. (S)-Norcoclaurine synthase (EC 3.5.99.14) , formerly known as (S)-norlaudanosoline synthase, will also catalyse the reaction of 4-(2-aminoethyl) benzene-1,2-diol + (3,4-dihydroxyphenyl) acetaldehyde to form (S)-norlaudanosoline.
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-
- HY-155907
-
|
DSPE-PEG5000-NH2 ammonium
|
Liposome
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Others
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DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
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-
- HY-W012952R
-
|
trans,trans-2,4-Heptadienall (Standard)
|
Biochemical Assay Reagents
Reference Standards
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Others
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(2E,4E)-Hepta-2,4-dienal (Standard) is the analytical standard of (2E,4E)-Hepta-2,4-dienal. This product is intended for research and analytical applications. (2E,4E)-Hepta-2,4-dienal is a naturally occurring organic compound that belongs to the group of aldehydes. It is an unsaturated aldehyde with two conjugated double bonds, giving it unique chemical and physical properties. (2E,4E)-Hepta-2,4-dienal is commonly found in various plant sources, especially in spices such as parsley and coriander. It is used as a flavoring agent and food additive in the formulation of various foods such as baked goods, snacks and beverages. It is also used in the fragrance industry, especially in the production of perfume and cologne.
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-
- HY-W440823A
-
|
DSPE-PEG1000-NH2 ammonium
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .
|
-
- HY-W800618
-
|
|
ADC Linker
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Others
|
|
NH2-PEG3-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
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-
- HY-W800617
-
|
|
ADC Linker
|
Cancer
|
|
NH2-PEG1-Val-Cit-PAB-OH is a cleavable ADC linker intermediate featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
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-
- HY-W800619
-
|
|
ADC Linker
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Others
|
|
NH2-PEG4-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
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-
- HY-W800620
-
|
|
ADC Linker
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Others
|
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NH2-PEG6-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
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-
- HY-W009411
-
|
|
Fluorescent Dye
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Others
|
|
Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease .
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-
- HY-P991906
-
|
CD22-4AP Antibody; CAT-02-106 Antibody
|
ADC Antibody
CD22
|
Cancer
|
|
TRPH-222 Antibody (CD22-4AP Antibody) is an anti-human CD22 antibody site-specifically modified at one site per heavy chain to express formylglycine (FG), allowing site-specific conjugation of a maytansinoid payload, a protease-insensitive spacer, and a functional group for coupling to an aldehyde on antibody FG residues. TRPH-222 Antibody can generate antibody drug conjugate (ADC) (TRPH-222) with an ADC payload and a linker. TRPH-222 Antibody can be used for the study of NHL (non-Hodgkin's lymphoma) .
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-
- HY-D1861
-
|
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Fluorescent Dye
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Others
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Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-W009411S
-
|
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Isotope-Labeled Compounds
Fluorescent Dye
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Others
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Dansyl hydrazine- 13C2 is the 13C-labeled Dansyl hydrazine (HY-W009411). Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease.
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-
- HY-D2772
-
|
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Biochemical Assay Reagents
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Others
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5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).
Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.
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-
| Cat. No. |
Product Name |
Type |
-
- HY-128692
-
|
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Fluorescent Dyes
|
|
Luc Yellow CH dilithium is a high-intensity fluorescent probe containing free hydrazyl groups. Luc Yellow CH can react with fatty aldehydes at room temperature. Luc Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Luc Yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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-
- HY-W127715
-
|
|
Fluorescent Dyes
|
|
Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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-
- HY-D1336
-
|
|
Fluorescent Dyes
|
|
FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.
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-
- HY-W998707
-
|
|
Fluorescent Dyes
|
|
TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-D2502
-
|
|
Fluorescent Dyes
|
|
Cy7 hydrazide is a Cy7 (HY-D0825) dye derivative with hydrazine functionality. The hydrazide group of Cy7 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
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-
- HY-D2772
-
|
|
Fluorescent Dyes
|
|
5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).
Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
-
- HY-132263
-
|
|
Fluorescent Dyes
|
|
FAM hydrazide, 5-isomer is a Fluorescein dye linker containing a hydrazide group. Fluorescein is a universal dye. Hydrazide moieties react with aldehydes to form semi-permanent hydrazone bonds.
|
-
- HY-172284
-
|
|
Fluorescent Dyes
|
|
6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
|
-
- HY-D2388
-
|
|
Fluorescent Dyes
|
|
Sulfo Cy5.5-hydrazide is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
|
-
- HY-D1861
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-W840196
-
|
|
Fluorescent Dyes
|
|
Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
|
-
- HY-D2388A
-
|
|
Fluorescent Dyes
|
|
Sulfo Cy5.5-hydrazide sodium is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide sodium can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W440823A
-
|
DSPE-PEG1000-NH2 ammonium
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .
|
-
- HY-W879045
-
|
Endo-BCN-PEG5-NH2
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-W018829
-
|
Undecylenic aldehyde
|
Biochemical Assay Reagents
|
|
10-Undecenal consists of an 11-carbon chain with a double bond between the 9th and 10th carbon atoms and an aldehyde group attached to the 1st carbon atom. This compound has a pungent or fatty smell and is commonly used as a flavoring commodity in foods such as bakery, confectionary and beverages.
|
-
- HY-W047710
-
|
|
Biochemical Assay Reagents
|
|
D-Galactal is a monosaccharide that belongs to the class of carbohydrates. It is an aldohexose, which means it has six carbon atoms and an aldehyde functional group. D-Galactal occurs naturally in certain foods such as dairy products, meats and fruits. It can also be synthesized by chemical or enzymatic processes. D-Galactal has various applications in the food industry, especially as a flavoring and sweetening agent. Additionally, it has potential research roles in metabolic disorders, cancer, and inflammation.
|
-
- HY-W017425
-
|
Phenylhydrazine acetate
|
Biochemical Assay Reagents
|
|
N'-Phenylacetohydrazide consists of a phenyl group attached to the acetylhydrazide functional group via a hydrazine bond. This compound is commonly used as a reagent in organic chemistry for the determination of carbonyl compounds such as aldehydes and ketones.
|
-
- HY-W142618
-
|
|
Biochemical Assay Reagents
|
|
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.
|
-
- HY-W009411
-
|
|
Biochemical Assay Reagents
|
|
Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease .
|
-
- HY-176509A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .
|
-
- HY-155908
-
|
DSPE-PEG10000-NH2 ammonium
|
Biochemical Assay Reagents
|
|
DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-155907
-
|
DSPE-PEG5000-NH2 ammonium
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-172379A
-
|
|
Biochemical Assay Reagents
|
|
Alginate aldehyde, 35% aldehyde content is an anionic polysaccharide widely used in pharmaceutical and biomedical applications. Aldehyde-functionalized Alginate aldehyde can be used to prepare hydrogels by reacting with amine groups .
|
-
- HY-176509C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .
|
-
- HY-176509
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .
|
-
- HY-W588728
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W1048547J
-
|
HOOC-PEG40000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG40000-NH2 (HOOC-PEG40000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W879032
-
|
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-W879025
-
|
Endo-BCN-PEG8-NH2
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-174948
-
|
NHS-PEG1000-aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-174948C
-
|
NHS-PEG5000-aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-172379
-
|
|
Biochemical Assay Reagents
|
|
Alginate aldehyde, 20% aldehyde content is an anionic polysaccharide widely used in pharmaceutical and biomedical applications. Aldehyde-functionalized Alginate aldehyde can be used to prepare hydrogels by reacting with amine groups .
|
-
- HY-174930
-
|
|
Biochemical Assay Reagents
|
|
Amino-PEG41-alcohol is a PEG derivative consisting of an alcohol, PEG unit and an amino group. The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds .
|
-
- HY-W588736
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-174916
-
|
|
Biochemical Assay Reagents
|
|
Amine-PEG1-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 1 PEG unit, and an amino group (Amine). Desthiobiotin is a biotin analog that has a weak but reversible binding ability to streptavidin or avidin. The amino group is able to react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-176509D
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery .
|
-
- HY-176509B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .
|
-
- HY-176509H
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG40000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG40000-CHO can be used for drug delivery .
|
-
- HY-W1048574I
-
|
OHC-PEG3400-carboxyl
|
Biochemical Assay Reagents
|
|
OHC-PEG3400-COOH (OHC-PEG3400-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG3400-COOH can be used for drug delivery .
|
-
- HY-W1048574E
-
|
OHC-PEG20000-carboxyl
|
Biochemical Assay Reagents
|
|
OHC-PEG20000-COOH (OHC-PEG20000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG20000-COOH can be used for drug delivery .
|
-
- HY-W879044
-
|
Endo-BCN-PEG15-NH2
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG15-amine (Endo-BCN-PEG15-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-W1049075E
-
|
|
Biochemical Assay Reagents
|
|
mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075B
-
|
|
Biochemical Assay Reagents
|
|
mPEG10000-Pald is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075D
-
|
|
Biochemical Assay Reagents
|
|
mPEG40000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W012952R
-
|
trans,trans-2,4-Heptadienall (Standard)
|
Biochemical Assay Reagents
|
|
(2E,4E)-Hepta-2,4-dienal (Standard) is the analytical standard of (2E,4E)-Hepta-2,4-dienal. This product is intended for research and analytical applications. (2E,4E)-Hepta-2,4-dienal is a naturally occurring organic compound that belongs to the group of aldehydes. It is an unsaturated aldehyde with two conjugated double bonds, giving it unique chemical and physical properties. (2E,4E)-Hepta-2,4-dienal is commonly found in various plant sources, especially in spices such as parsley and coriander. It is used as a flavoring agent and food additive in the formulation of various foods such as baked goods, snacks and beverages. It is also used in the fragrance industry, especially in the production of perfume and cologne.
|
-
- HY-174948B
-
|
NHS-PEG3400-aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG3400-CHO (NHS-PEG3400-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-174948A
-
|
NHS-PEG2000-aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG2000-CHO (NHS-PEG2000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-174932
-
|
|
Biochemical Assay Reagents
|
|
Amino-PEG18-t-butyl ester is a PEG derivative consisting of t-butyl ester, PEG unit and an amino group (Amine). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W1123946H
-
|
|
Biochemical Assay Reagents
|
|
8-Arm-PEG10000-CHO is a polyethylene glycol derivative with multiple active aldehyde groups, which can be used to construct drug delivery carriers .
|
-
- HY-W1123946A
-
|
|
Biochemical Assay Reagents
|
|
8-Arm-PEG40000-CHO is a polyethylene glycol derivative with multiple active aldehyde groups, which can be used to construct drug delivery carriers .
|
-
- HY-W1123946
-
|
|
Biochemical Assay Reagents
|
|
8-Arm-PEG20000-CHO is a polyethylene glycol derivative with multiple active aldehyde groups, which can be used to construct drug delivery carriers .
|
-
- HY-W793100
-
|
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG2-Biotin is a PEG linker containing a BCN group and a terminal carboxylic acid. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-176509E
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG20000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG20000-CHO can be used for drug delivery .
|
-
- HY-W1048574J
-
|
OHC-PEG40000-carboxyl
|
Biochemical Assay Reagents
|
|
OHC-PEG40000-COOH (OHC-PEG40000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG40000-COOH can be used for drug delivery .
|
-
- HY-W1048574H
-
|
OHC-PEG1000-carboxyl
|
Biochemical Assay Reagents
|
|
OHC-PEG1000-COOH (OHC-PEG1000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG1000-COOH can be used for drug delivery .
|
-
- HY-W1048574A
-
|
OHC-PEG2000-carboxyl
|
Biochemical Assay Reagents
|
|
OHC-PEG2000-COOH (OHC-PEG2000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG2000-COOH can be used for drug delivery .
|
-
- HY-W1048574D
-
|
OHC-PEG10000-carboxyl
|
Biochemical Assay Reagents
|
|
OHC-PEG10000-COOH (OHC-PEG10000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG10000-COOH can be used for drug delivery .
|
-
- HY-W1048574C
-
|
OHC-PEG5000-carboxyl
|
Biochemical Assay Reagents
|
|
OHC-PEG5000-COOH (OHC-PEG5000-carboxyl) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG5000-COOH can be used for drug delivery .
|
-
- HY-W1048547A
-
|
HOOC-PEG2000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG2000-NH2 (HOOC-PEG2000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547H
-
|
HOOC-PEG1000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG1000-NH2 (HOOC-PEG1000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547E
-
|
HOOC-PEG20000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG20000-NH2 (HOOC-PEG20000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547I
-
|
HOOC-PEG3400-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG3400-NH2 (HOOC-PEG3400-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-W1048547C
-
|
HOOC-PEG5000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG5000-NH2 (HOOC-PEG5000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-W1048547D
-
|
HOOC-PEG10000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG10000-NH2 (HOOC-PEG10000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-183171
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG1000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG1000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183171D
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG10000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG10000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183171B
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG5000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG5000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183171C
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG3400-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG3400-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183171A
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG2000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183398B
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG3400-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG3400-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183398A
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG2000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183398D
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG10000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG10000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183398C
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG5000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG5000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183398
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG1000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG1000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-W1049075H
-
|
|
Biochemical Assay Reagents
|
|
mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
- HY-W1049075C
-
|
|
Biochemical Assay Reagents
|
|
mPEG20000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
- HY-W1049075A
-
|
|
Biochemical Assay Reagents
|
|
mPEG5000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
- HY-W1049075
-
|
|
Biochemical Assay Reagents
|
|
mPEG1000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
- HY-W018829R
-
|
Undecylenic aldehyde (Standard)
|
Biochemical Assay Reagents
|
|
10-Undecenal (Standard) is the analytical standard of 10-Undecenal (HY-W018829). This product is intended for research and analytical applications. 10-Undecenal consists of an 11-carbon chain with a double bond between the 9th and 10th carbon atoms and an aldehyde group attached to the 1st carbon atom. This compound has a pungent or fatty smell and is commonly used as a flavoring commodity in foods such as bakery, confectionary and beverages.
|
| Cat. No. |
Product Name |
Target |
Research Area |
Image |
-
- HY-P991906
-
|
CD22-4AP Antibody; CAT-02-106 Antibody
|
ADC Antibody
CD22
|
Cancer
|
|
TRPH-222 Antibody (CD22-4AP Antibody) is an anti-human CD22 antibody site-specifically modified at one site per heavy chain to express formylglycine (FG), allowing site-specific conjugation of a maytansinoid payload, a protease-insensitive spacer, and a functional group for coupling to an aldehyde on antibody FG residues. TRPH-222 Antibody can generate antibody drug conjugate (ADC) (TRPH-222) with an ADC payload and a linker. TRPH-222 Antibody can be used for the study of NHL (non-Hodgkin's lymphoma) .
|
-
(5)
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W018829
-
-
-
- HY-N15067
-
-
-
- HY-118118
-
|
|
Microorganisms
Antibiotics
Other Antibiotics
Source Classification
|
Fungal
|
|
Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite with strong antifungal activity. Phlebiakauranol aldehyde exhibits significant antibacterial and cytotoxic activities against a variety of plant pathogens. The aldehyde group and high number of hydroxyl groups of Phlebiakauranol aldehyde are considered to be the main reasons for its biological activity. The two acetic acid derivatives of Phlebiakauranol aldehyde only exhibit very weak antifungal and antibacterial activities and moderate cytotoxic activity .
|
-
-
- HY-W012952R
-
|
trans,trans-2,4-Heptadienall (Standard)
|
Natural Products
Vaccinium macrocarpon Aiton
Ericaceae
Plants
Source Classification
|
Biochemical Assay Reagents
Reference Standards
|
|
(2E,4E)-Hepta-2,4-dienal (Standard) is the analytical standard of (2E,4E)-Hepta-2,4-dienal. This product is intended for research and analytical applications. (2E,4E)-Hepta-2,4-dienal is a naturally occurring organic compound that belongs to the group of aldehydes. It is an unsaturated aldehyde with two conjugated double bonds, giving it unique chemical and physical properties. (2E,4E)-Hepta-2,4-dienal is commonly found in various plant sources, especially in spices such as parsley and coriander. It is used as a flavoring agent and food additive in the formulation of various foods such as baked goods, snacks and beverages. It is also used in the fragrance industry, especially in the production of perfume and cologne.
|
-
-
- HY-W018829R
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W009411S
-
|
|
|
Dansyl hydrazine- 13C2 is the 13C-labeled Dansyl hydrazine (HY-W009411). Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease.
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W879045
-
|
Endo-BCN-PEG5-NH2
|
|
BCN
|
|
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-W590569
-
|
|
|
Azide
|
|
Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.
|
-
- HY-138518
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-176846
-
|
|
|
Alkynes
|
|
HIPS probe-1 (Compound 1) is a click chemistry reagent containing a alkyne group. HIPS probe-1 can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. HIPS probe-1 can be used as a chemical probe to specifically recognize and label aldehyde functional groups in DNA, especially abasic sites (AP sites) for DNA damage research .
|
-
- HY-136054
-
|
|
|
ADC Synthesis
Azide
|
|
N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-135977
-
|
|
|
DBCO
ADC Synthesis
|
|
DBCO-SS-aldehyde is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-SS-aldehyde is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W588728
-
|
|
|
DBCO
|
|
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W879032
-
|
|
|
BCN
|
|
Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-136074
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136077
-
|
|
|
TCO
ADC Synthesis
|
|
(S)-TCO-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . (S)-TCO-PEG3-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-136076
-
|
|
|
TCO
ADC Synthesis
|
|
TCO-PEG3-CH2-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-CH2-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-136140
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Aldehyde-benzyl-PEG5-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133465
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Tetrazine-Ph-PEG4-Ph-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG4-Ph-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W588736
-
|
|
|
DBCO
|
|
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W800657
-
|
|
|
Azide
|
|
Azido-PEG1-hydrazide hydrochloride is a bifunctional PEG linker containing an azide group and a hydrazide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds.
|
-
- HY-W840196
-
|
|
|
Alkynes
|
|
Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W440823A
-
|
DSPE-PEG1000-NH2 ammonium
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .
|
-
- HY-176509A
-
|
|
|
Pegylated Lipids
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DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .
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- HY-155908
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DSPE-PEG10000-NH2 ammonium
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Pegylated Lipids
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DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
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- HY-155907
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DSPE-PEG5000-NH2 ammonium
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Pegylated Lipids
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DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
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- HY-176509C
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Pegylated Lipids
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DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .
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- HY-176509
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Pegylated Lipids
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DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .
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- HY-176509D
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Pegylated Lipids
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DSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery .
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- HY-176509B
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Pegylated Lipids
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DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .
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- HY-176509H
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Pegylated Lipids
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DSPE-PEG40000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG40000-CHO can be used for drug delivery .
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- HY-176509E
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Pegylated Lipids
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DSPE-PEG20000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG20000-CHO can be used for drug delivery .
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