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Results for "

anorexia

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Autophagy (1) Cannabinoid Receptor (1) Drug Metabolite (1) GHSR (6) Glucocorticoid Receptor (3) HDAC (1) HIV (1) Isotope-Labeled Compounds (2) MCHR1 (GPR24) (1) Melanocortin Receptor (5) Neuropeptide Y Receptor (1) Opioid Receptor (1) Progesterone Receptor (4) Reference Standards (2)
By Research Areas:	Cancer (11) Cardiovascular Disease (1) Endocrinology (9) Infection (3) Inflammation/Immunology (6) Metabolic Disease (4) Neurological Disease (11)

Inhibitors & Agonists

Peptides

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13676

Megestrol acetate 2 Publications Verification	Progesterone Receptor Autophagy HIV	Endocrinology Cancer
Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway .

HY-14734

Anamorelin Maximum Cited Publications 9 Publications Verification RC-1291; ONO-7643	GHSR	Endocrinology Cancer
Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia .

HY-148349

PF-07258669 1 Publications Verification	Melanocortin Receptor	Neurological Disease Metabolic Disease
PF-07258669 is an orally active melanocortin-4 receptor (MC4R) antagonist that antagonizes MC4R with an IC₅₀ of 13 nM (K_i=0.46 nM). PF-07258669 can be used for the research of cachexia, anorexia, or anorexia nervosa .

HY-14820A

Macimorelin acetate EP-1572 acetate; AEZS-130 acetate	GHSR	Neurological Disease Endocrinology Cancer
Macimorelin (EP-1572) acetate, a GH secretagogue, is an orally active GHSR agonist. Macimorelin acetate stimulates GH release. Macimorelin acetate can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS) .

HY-14734A

Anamorelin hydrochloride Maximum Cited Publications 9 Publications Verification RC-1291 hydrochloride; ONO-7643 hydrochloride	GHSR	Endocrinology Cancer
Anamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia .

HY-14450

JNJ-31020028 1 Publications Verification	Neuropeptide Y Receptor	Neurological Disease Endocrinology
JNJ-31020028 is a selective and brain penetrant antagonist of neuropeptide Y Y2 receptor with pIC₅₀ values of 8.07 and 8.22 for human and rat Y2 receptor, respectively. JNJ-31020028 can be used for the research of nervous disease .

HY-12844

Ro 64-6198 1 Publications Verification	Opioid Receptor	Neurological Disease
Ro 64-6198 is a potent, selective, nonpeptide, high-affinity, high cellular permeability and brain penetration N/OFQ receptor (NOP) agonist with an EC₅₀ value of 25.6 nM. Ro 64-6198 is at least 100 times more selective for the NOP receptor over the classic opioid receptors. Ro 64-6198 can be used for stress and anxiety, addiction, neuropathic pain, cough, and anorexia .

HY-B1834

Megestrol	Progesterone Receptor Glucocorticoid Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Megestrol is an orally active glucocorticoid and progesterone receptor agonist. Megestrol can alleviate anorexia, cachexia or unexplained significant weight loss associated with acquired immunodeficiency syndrome (AIDS). Megestrol may cause manifestations similar to those of glucocorticoids and increase the risk of mental disorders .

HY-12095

CB1 inverse agonist 2	Cannabinoid Receptor	Neurological Disease
CB1 inverse agonist 2 is an orally active inverse agonist of Cannabinoid Receptor CB1. CB1 inverse agonist 2 effectively inhibits CP55940-induced hypothermia and anorexia in mice model .

HY-135552

Benoxathian hydrochloride	Adrenergic Receptor	Endocrinology
Benoxathian hydrochloride is a potent α1 adrenoceptor antagonist, can be used for researching anorexia .

HY-14820

Macimorelin EP-1572; AEZS-130	GHSR	Endocrinology Cancer
Macimorelin (EP-1572), a GH secretagogue, is an orally active GHSR agonist. Macimorelin stimulates GH release. Macimorelin can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS) .

HY-W039283

MCH-1 antagonist 2	MCHR1 (GPR24)	Neurological Disease Cancer
MCH-1 antagonist 2 (l-BROMO-2,4-DIFLUORO-5-NITROBEN-ZENE) is a melanin concentrating hormone-1 (MCH1) receptor-selective 4-aryl piperidine. MCH-1 antagonist 2 can be used for the research of depression, anxiety, obesity, urge incontinence, urinary incontinence, major depression, bipolar disorder, agoraphobia, specific phobia, social phobia, obsessive-compulsive disorder, post-traumatic stress disorder, acute stress disorder, urinary frequency, urinary urgency, nocturia, enuresis, bulimia, bulimia nervosa, anorexia nervosa, major depressive disorder, dysthymic disorder, bipolar 1 and 2 disorders, schizoaffective disorder, cognitive disorders with depressed mood, personality disorders, insomnia, hypersomnia, narcolepsy, circadian rhythm sleep disorder, nightmare disorder, sleep terror disorder, sleepwalking disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, overactive bladder .

HY-107627

MCL0020	Melanocortin Receptor	Inflammation/Immunology
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC₅₀ of 11.63 nM. MCL0020 dose-dependently and significantly attenuates restraint stress-induced anorexia without affecting food intake .

HY-P10985

CTX-1211	Melanocortin Receptor	Metabolic Disease
CTX-1211 is a selective, orally effective melanocortin MC4R agonist (EC₅₀=0.38 nM). CTX-1211 can enhance the feeding suppression and weight loss effects induced by liraglutide (HY-P0014), and promote anorexia and weight loss activity. CTX-1211 is mainly used in the study of obesity and other metabolic disorders .

HY-W747043

Megestrol-d3	Isotope-Labeled Compounds Drug Metabolite	Inflammation/Immunology
Megestrol-d₃ is the deuterium labeled Megestrol (HY-B1834). Megestrol is a synthetic progestin and used for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis .

HY-174449

HDAC6-IN-62	HDAC	Neurological Disease
HDAC6-IN-62 (Compound 2.12) is a selective HDAC6 inhibitor, with an IC₅₀ value of 0.25 nM. HDAC6-IN-62 can be used in the research of Charcot-Marie-Tooth disease .

HY-14734B

Anamorelin Fumarate RC-1291 Fumarate; ONO-7643 Fumarate	GHSR	Endocrinology Cancer
Anamorelin (RC-1291) Fumarate is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin Fumarate can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin Fumarate can be used in the research of anorexia and cancer cachexia .

HY-B1834S1

Megestrol-d5	Isotope-Labeled Compounds Progesterone Receptor Glucocorticoid Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Megestrol-d₅ is the deuterium labeled Megestrol. Megestrol is an orally active glucocorticoid and progesterone receptor agonist. Megestrol can alleviate anorexia, cachexia or unexplained significant weight loss associated with acquired immunodeficiency syndrome (AIDS). Megestrol may cause glucocorticoid-like effects and an increased risk of mental disorders.

HY-B1834R

Megestrol (Standard)	Reference Standards Progesterone Receptor Glucocorticoid Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Megestrol (Standard) is the analytical standard of Megestrol. This product is intended for research and analytical applications. Megestrol is an orally active glucocorticoid and progesterone receptor agonist. Megestrol can alleviate anorexia, cachexia or unexplained significant weight loss associated with acquired immunodeficiency syndrome (AIDS). Megestrol may cause manifestations similar to those of glucocorticoids and increase the risk of mental disorders.

HY-14734R

Anamorelin (Standard) RC-1291 (Standard); ONO-7643 (Standard)	Reference Standards GHSR	Endocrinology Cancer
Anamorelin (Standard) (RC-1291 (Standard)) is the analytical standard of Anamorelin (HY-14734). This product is intended for research and analytical applications. Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia .

HY-182773

MC4R Antagonist-1	Melanocortin Receptor	Metabolic Disease
MC4R Antagonist-1 (compound 1) is an MC4R-selective antagonist (IC₅₀<10 nM). MC4R Antagonist-1 can be used for the research of cachexia, anorexia, anorexia nervosa, involuntary weight loss, failure to thrive, sarcopenia, muscle wasting, muscle weakness, frailty, osteoporosis .

HY-183106

MC4R antagonist-2	Melanocortin Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
MC4R antagonist-2 is a potent melanocortin 4 receptor (MC4R) antagonist with an IC₅₀ of 0.54 nM. MC4R antagonist-2 can be used for the research of MC4R-mediated conditions, such as cachexia, osteoporosis, neuropathic pain, depression, hypertension, malnutrition-related obesity, and associated inflammatory diseases .

Cat. No.	Product Name	Target	Research Area

HY-107627

MCL0020	Melanocortin Receptor	Inflammation/Immunology
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC₅₀ of 11.63 nM. MCL0020 dose-dependently and significantly attenuates restraint stress-induced anorexia without affecting food intake .

HY-P10985

CTX-1211	Melanocortin Receptor	Metabolic Disease
CTX-1211 is a selective, orally effective melanocortin MC4R agonist (EC₅₀=0.38 nM). CTX-1211 can enhance the feeding suppression and weight loss effects induced by liraglutide (HY-P0014), and promote anorexia and weight loss activity. CTX-1211 is mainly used in the study of obesity and other metabolic disorders .

Cat. No.	Product Name	Chemical Structure

HY-W747043

Megestrol-d3
Megestrol-d₃ is the deuterium labeled Megestrol (HY-B1834). Megestrol is a synthetic progestin and used for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis .

HY-B1834S1

Megestrol-d5
Megestrol-d₅ is the deuterium labeled Megestrol. Megestrol is an orally active glucocorticoid and progesterone receptor agonist. Megestrol can alleviate anorexia, cachexia or unexplained significant weight loss associated with acquired immunodeficiency syndrome (AIDS). Megestrol may cause glucocorticoid-like effects and an increased risk of mental disorders.

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