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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
antibody-dependent cell-mediated cytotoxicity (ADCC)
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "antibody-dependent cell-mediated cytotoxicity (ADCC)" in MCE Product Catalog:
11
11 Publications Verification
Cat. No.: HY-108730
CAS No.: 1537032-82-8
Synonyms: Anti-Human PD-L1, Human antibody; MSB 0010718C; MSB0010718C
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11 Publications Verification
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Cat. No.: HY-P9948
CAS No.: 216503-57-0
Synonyms: Campath-IH
Cat. No.: HY-P99361
CAS No.: 1062149-33-0
Synonyms: PDL192; ABT-361; Anti-TNFRSF12A/TWEAKR/CD266 Reference antibody (enavatuzumab)
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Cat. No.: HY-P9961
CAS No.: 679818-59-8
Synonyms: GSK1841157; OMB-157
Cat. No.: HY-P99167
CAS No.: 903512-50-5
Synonyms: HCD122
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Cat. No.: HY-P991669
Synonyms: AML-01
Cat. No.: HY-P99304
CAS No.: 1448327-63-6
Synonyms: Anti-Human ERBB3 Recombinant antibody
Cat. No.: HY-P99308
CAS No.: 1169956-08-4
Synonyms: AME 133v; LY 2469298; Humanized Anti-MS4A1 Recombinant antibody
Cat. No.: HY-P99746
CAS No.: 2058047-65-5
Synonyms: 3C23K; GM102
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Cat. No.: HY-177578
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NN3201 is a c-Kit-targeting antibody-drug conjugate (ADC) with high affinity (KD = 0.19 pM). NN3201 is composed of 4-(3-Tosyl-2-(tosylmethyl)propanoyl)benzoic acid-glu(PEG24-Me)-val-cit-NH-benzyloxyformic acid-MMAE (HY-178219) and an anti-c-Kit human monoclonal antibody NN2101 (HY-P991293). NN3201 rapidly internalizes and inhibits stem cell factor (SCF)-driven signaling, thereby delivering its payload to induce cell cycle arrest and apoptosis. NN3201 exhibits no Fc-mediated effector functions antibody-dependent cell-mediated cytotoxicity (ADCC)/complement-dependent cytotoxicity (CDC) due to reduced FcγR binding. NN3201 exhibits significant c-Kit-dependent anti-tumor efficacies in various tumor models. NN3201 can be used in small cell lung cancer (SCLC) and gastrointestinal stromal tumor (GIST) and acute myeloid leukemia (AML) research [1][2].
Cat. No.: HY-P99622
CAS No.: 1188277-05-5
Synonyms: IMC-20D7S
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Cat. No.: HY-P991660
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Cat. No.: HY-P991638
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Cat. No.: HY-P9968A
CAS No.: 780758-10-3
Cat. No.: HY-P991514
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
