Search Result

Results for "

antiproliferative， anticancer

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) ADC Payload (4) Akt (5) Aldehyde Dehydrogenase (ALDH) (2) AMPK (1) Antibiotic (1) Apoptosis (86) ATP Synthase (1) Autophagy (7) Bacterial (14) Bcl-2 Family (8) Bcr-Abl (1) Biochemical Assay Reagents (1) Btk (1) c-Met/HGFR (2) Carbonic Anhydrase (1) Caspase (7) CDK (14) Checkpoint Kinase (Chk) (1) COX (4) CXCR (1) Cytochrome P450 (4) Dengue Virus (1) Deubiquitinase (1) DNA Alkylator/Crosslinker (1) DNA-PK (2) DNA/RNA Synthesis (10) Drug Derivative (12) Drug Intermediate (3) Drug Isomer (1) Drug Metabolite (1) E1/E2/E3 Enzyme (1) EBV (2) EGFR (11) Endogenous Metabolite (3) Environmental Pollutants (2) ERK (8) Estrogen Receptor/ERR (1) Fat Mass and Obesity-associated Protein (FTO) (1) Fatty Acid Synthase (FASN) (1) Ferroptosis (2) Flavivirus (1) FLT3 (2) Fungal (3) Glutaminase (1) GSK-3 (1) HDAC (13) Hedgehog (2) Herbicide (1) HIF/HIF Prolyl-Hydroxylase (4) Histone Acetyltransferase (3) Histone Demethylase (1) Histone Methyltransferase (5) HSP (1) IAP (1) Influenza Virus (2) Interleukin Related (1) Isotope-Labeled Compounds (2) JAK (1) JNK (3) Kinesin (1) Lipoxygenase (1) MAP3K (1) MAPKAPK2 (MK2) (1) MDM-2/p53 (7) Methionine Adenosyltransferase (MAT) (1) MicroRNA (1) Microtubule/Tubulin (20) Mitochondrial Metabolism (1) Mitophagy (2) Mitosis (2) MMP (1) Molecular Glues (1) Monoamine Oxidase (1) mTOR (1) Necroptosis (2) NF-κB (4) NO Synthase (1) NOD-like Receptor (NLR) (1) Notch (1) Nucleoside Antimetabolite/Analog (2) P-glycoprotein (3) p38 MAPK (3) PAK (1) Parasite (5) PARP (4) PDGFR (1) PERK (1) Phosphatase (2) PI3K (2) Pim (2) PKC (1) Polo-like Kinase (PLK) (6) PROTACs (4) Proteasome (2) Proton Pump (1) Pyruvate Kinase (2) Quinone Reductase (1) Raf (1) Ras (6) Reactive Oxygen Species (ROS) (11) Reference Standards (11) RIO Kinase (1) SHP1 (1) SHP2 (1) Sigma Receptor (1) Sirtuin (1) Smo (2) STAT (2) Telomerase (2) TNF Receptor (1) Topoisomerase (4) Tyrosinase (2) VD/VDR (1) VEGFR (3) Wnt (4) β-glucuronidase (1)
By Research Areas:	Cancer (226) Infection (19) Inflammation/Immunology (20) Metabolic Disease (5) Neurological Disease (16)
Click Chemistry:	Alkynes (1)

230

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148185

T01-1 KL610023	ADC Payload	Cancer
T01-1 is an anticancer agent (camptothecin derivative) with good anti-proliferative activity .

HY-N1497

Plumbagin 3 Publications Verification 2-Methyljuglone	Others	Cancer
Plumbagin (2-Methyljuglone) is a naphthoquinone isolated from Plumbago zeylanica, exhibits anticancer and antiproliferative activities .

HY-12025

Serdemetan 3 Publications Verification JNJ-26854165	MDM-2/p53 E1/E2/E3 Enzyme Apoptosis	Cancer
Serdemetan (JNJ-26854165) is a potent *anticancer* agent with radiosensitizing activity. Serdemetan exhibits antiproliferative activity in various p53 wild-type tumor cells. Serdemetan also antagonizes the Mdm2-HIF1α axis leading to decreased levels of glycolytic enzymes .

HY-76316

Bergaptol 5-Hydroxypsoralen; 4-Hydroxybergapten	Cytochrome P450	Neurological Disease Inflammation/Immunology Cancer
Bergaptol is an inhibitor of debenzylation of the CYP3A4 enzyme with an IC₅₀ of 24.92 μM. Recent studies have shown that it has anti-proliferative and anti-cancer properties .

HY-122727

STL127705 5+ Cited Publications	DNA-PK Apoptosis	Cancer
STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor with an IC₅₀ of 3.5 μM. STL127705 interferes the binding of Ku70/80 to DNA and by inhibits the activation of the DNA-PKCS kinase. STL127705 shows antiproliferative and anticancer activity. STL127705 induces apoptosis .

HY-W016889

CFL-137	Ras	Cancer
CFL-137 is a potent KRas ^G12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer .

HY-126052

Gnetol	COX Tyrosinase HDAC	Metabolic Disease Cancer
Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC₅₀ of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC₅₀ of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities .

HY-119502

Camalexin 3 Publications Verification	Reactive Oxygen Species (ROS) Fungal Bacterial	Infection Cancer
Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production .

HY-148740

Werner syndrome RecQ helicase-IN-3	DNA/RNA Synthesis	Cancer
Werner syndrome RecQ helicase-IN-3 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC₅₀ value of 0.06 µM. Werner syndrome RecQ helicase-IN-3 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-3 shows anticancer activity .

HY-129476

L-Canaline	Parasite Endogenous Metabolite	Infection Cancer
L-Canaline is a nonprotein amino acid stored in many leguminous plants. L-Canaline is a cytotoxic metabolite catalyzed by L-canavanine and its arginase. L-Canaline is a potent and irreversible inhibitor of ornithine aminotransferase. L-Canaline inhibits the growth of the malaria parasite *Plasmodium falciparum* with an IC₅₀ of 297 nM. L-Canaline has anticancer and antiproliferative effects .

HY-N7015

Zerumbone 2 Publications Verification	EBV Caspase Apoptosis Bacterial	Infection Cancer
Zerumbone is an orally active natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet. Zerumbone has anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity .

HY-146682

KS100	Aldehyde Dehydrogenase (ALDH) Apoptosis	Cancer
KS100 is a potent ALDH inhibitor with IC₅₀s of 230, 1542, 193 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively. KS100 shows antiproliferative and anticancer effects with low low toxic. KS100 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS10600 induces apoptosis and cell cycle arrest at the G2/M phase .

HY-153469

Benzyl DC-81	ADC Payload	Cancer
Benzyl DC-81 (Compound 6a) is an anticancer agent with antiproliferative activity against A375 and MCF-7 cells .

HY-N10544

δ-Cadinene (+)-δ-Cadinene	Bacterial Parasite Fungal Apoptosis	Infection Cancer
δ-Cadinene ((+)-δ-Cadinene) is a sesquiterpene in essential oils. δ-Cadinene shows antiproliferative and pro-apoptotic effects on human ovary cancer (OVCAR-3) cells. δ-Cadinene has trichomonacidal, antimicrobial, antifungal and anticancer properties .

HY-146683

KS106	Aldehyde Dehydrogenase (ALDH) Apoptosis	Cancer
KS106 is a potent ALDH inhibitor with IC₅₀s of 334, 2137, 360 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS106 induces apoptosis and cell cycle arrest at the G2/M phase .

HY-32344

Inecalcitol 1 Publications Verification TX 522	VD/VDR Apoptosis	Cancer
Inecalcitol (TX 522), a unique vitamin D3 analog, is an orally active vitamin D receptor (VDR) agonist with a K_d of 0.53 nM. Inecalcitol can induce cell apoptosis and has potent anticancer activities . Inecalcitol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147941

MS9427	PROTACs EGFR	Inflammation/Immunology Cancer
MS9427 is a potent PROTAC EGFR degrader with K_ds of 7.1 nM and 4.3 nM for EGFR WT and EGFR L858R, respectively. MS9427 selectively degrades the mutant but not the WT EGFR through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9427 potently inhibits the proliferation of NSCLC cells. MS9427 can be used for researching anticancer .

HY-W041315

CFL-120	Ras	Cancer
CFL-120 is a potent KRas ^G12C inhibitor. CFL-120 shows an antiproliferative effect. CFL-120 shows anticancer activity. CFL-120 has the potential for the research of lung cancer .

HY-148741

Werner syndrome RecQ helicase-IN-4	DNA/RNA Synthesis	Cancer
Werner syndrome RecQ helicase-IN-4 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC₅₀ value of 0.06 µM. Werner syndrome RecQ helicase-IN-4 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-4 shows anticancer activity .

HY-14307A

(R)-Necrocide 1	Drug Isomer	Cancer
(R)-Necrocide 1 (compound (R)-38) a potent anticancer agent. (R)-Necrocide 1 has antiproliferative activity .

HY-149920

Anticancer agent 98	Microtubule/Tubulin	Cancer
Anticancer agent 98 (compound 12k) is a microtubule/tubulin-polymerization inhibitor (K_d=16.9 μM). Anticancer agent 98 exerts antiproliferative potency against tumor cells, exhibits anti-angiogenesis effect in vitro. Anticancer agent 98 exhibits good human and mouse liver microsomes stability with both t_1/2>300 min .

HY-126423

Isorhamnetin 3-glucuronide Isorhamnetin 3-O-glucuronide	Apoptosis	Cancer
Isorhamnetin 3-glucuronide is a potent anticancer agent. Isorhamnetin 3-glucuronide shows anti-proliferative activity. Isorhamnetin 3-glucuronide induces Apoptosis and cell cycle arrest at S-phase .

HY-147941A

MS9427 TFA	PROTACs EGFR	Infection Inflammation/Immunology Cancer
MS9427 TFA is a potent PROTAC EGFR degrader with K_ds of 7.1 nM and 4.3 nM for EGFR WT and EGFR L858R, respectively. MS9427 TFA selectively degrades the mutant but not the WT EGFR through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9427 TFA potently inhibits the proliferation of NSCLC cells. MS9427 TFA can be used for researching anticancer .

HY-119502R

Camalexin (Standard)	Reference Standards Reactive Oxygen Species (ROS) Fungal Bacterial	Infection Cancer
Camalexin (Standard) is the analytical standard of Camalexin. This product is intended for research and analytical applications. Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production[1][2][3].

HY-W007977

4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline	Drug Intermediate	Cancer
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline (Compound 11 and 15) is a building block and synthetic intermediate, which can be used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer agents. 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline can also be used to synthesize EGFR inhibitors, including Erlotinib (HY-50896), with antiproliferative activity .

HY-168114

Multi-kinase inhibitor 3	FLT3 PDGFR VEGFR	Cancer
Multi-kinase inhibitor 3 (compound 12) is a potent and orally active multikinase inhibitor with IC₅₀ values of 1.59, 1.23, 1.19, 0.59, 0.22, 1.15 nM for FLT1/VEGFR1, KDR/VEGFR2, FLT4/VEGFR3, FLT3, PDGFRα, PDGFRβ, respectively. Multi-kinase inhibitor 3 shows antiproliferative activity. Multi-kinase inhibitor 3 shows anticancer activity .

HY-152090

Antiproliferative agent-17	Bacterial Sirtuin	Infection Cancer
Antiproliferative agent-17 is an antiproliferative agent. Antiproliferative agent-17 inhibits Gram-positive bacteria and has anticancer activity .

HY-175003

HV1-IN-2	Proton Pump	Cancer
HV1-IN-2 (Compound 14c) is a human voltage-gated proton channel (HV1) inhibitor with an IC₅₀ of 2.14 μM. HV1-IN-2 has a potent anticancer activity with significant antiproliferative effects against THP-1 and MCF-7 cells. HV1-IN-2 can be used for cancers research, such as colorectal tumours, leukaemia, and breast cancer .

HY-W278944

Antiproliferative agent-15	Drug Derivative	Cancer
Antiproliferative agent-15 is an thienopyrimidine derivated anticancer agent. Antiproliferative agent-15 shows antiproliferative activity against human colon (HCT116 and HCT15) and brain (LN-229 and GBM-10) cancer cell lines .

HY-148453

Antiproliferative agent-16	Drug Derivative	Cancer
Antiproliferative agent-16 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC₅₀ of 6.94 μM for MCF-7 cells) .

HY-147839

Topoisomerase II inhibitor 10	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 10 (compound 32a) is a potent topoisomerase II inhibitor with an IC₅₀ value of 7.45 μM. Topoisomerase II inhibitor 10 causes cell cycle arrest at G2-M phase and induces apoptosis of HepG-2 cells. Topoisomerase II inhibitor 10 has excellent anti-proliferative activities against HepG-2, MCF-7, and HCT-116 cells .

HY-N7640

Deoxylimonin	Others	Inflammation/Immunology Cancer
Desoxylimonin is an orally active triterpenoid compound found from grapefruit seed. Desoxylimonin shows anti-proliferative activities to breast cancer cells. Desoxylimonin derivatives shows better anticancer, analgesic and anti-inflammatory activity than the lead compound .

HY-142085

Antiproliferative agent-20	VEGFR	Cancer
Antiproliferative agent-20 is a potent and orally active anticancer agent. Antiproliferative agent-20 exhibits antiproliferative and anti-angiogenic activities .

HY-156777

Antiproliferative agent-36	Drug Derivative	Cancer
Antiproliferative agent-36 (compound 8i) is a benzothiazolyl hydrazones derived compound with antiproliferative activity. Antiproliferative agent-36 has a broad-spectrum anticancer activity .

HY-146030

Anticancer agent 46	Drug Derivative	Cancer
Anticancer agent 46 (compound 2) is a potent anticancer agent. Anticancer agent 46 shows antiproliferative activity with an IC₅₀ of 0.986 µM for MGC803 cells. Anticancer agent 46 has the potential for the research of gastric cancer .

HY-163619

Anticancer agent 227	Apoptosis Mitophagy	Cancer
Anticancer agent 227 (compound YNU-1c) is a potent anticancer agent. Anticancer agent 227 shows antiproliferative activity. Anticancer agent 227 induces apoptosis and mitophagy .

HY-176485

Antiproliferative agent-70	Ferroptosis Mitophagy Reactive Oxygen Species (ROS)	Cancer
Antiproliferative agent-70 (compound 23) is a potent antiproliferative agent. Antiproliferative agent-70 shows antiproliferative activities and induces MMP depolarization. Antiproliferative agent-70 induces mitochondrial dysfunction. Antiproliferative agent-70 induces mitophagy and ferroptosis. Antiproliferative agent-70 increases the protein expression of PINK1, p-Parkin, p53 and p21. Antiproliferative agent-70 increases intracellular ROS levels. Antiproliferative agent-70 shows anticancer activity .

HY-146063

Anticancer agent 54	Apoptosis	Cancer
Anticancer agent 54 is a potent anticancer agent. Anticancer agent 54 shows antiproliferative activity. Anticancer agent 54 induces apoptosis and cell cycle arrest at G0/G1 phases. Anticancer agent 54 shows anticancer activity depends on DNA intercalation and ROS generation .

HY-117423

ST7710AA1	PARP	Cancer
ST7710AA1 (compound 1l) is a potent PARP-1 inhibitor with an IC₅₀ value of 0.07 µM. ST7710AA1 shows an antiproliferative activity. ST7710AA1 shows anticancer activity .

HY-155112

Antiproliferative agent-30	Microtubule/Tubulin FLT3 Bcr-Abl	Cancer
Antiproliferative agent-30 (Compound 8g) inhibits tubulin assembly and inhibits FLT3 and Abl1. Antiproliferative agent-30 has vascular-disrupting activity. Antiproliferative agent-30 has broad antiproliferative activities against cancer cell lines (IC₅₀s: 0.054 nM, 0.008 nM, 0.144 nM for HCT-116, K562, MV-4-11 cells respectively). Antiproliferative agent-30 also has anticancer effect against AML with FLT3-ITD-TKD mutation .

HY-W016889R

CFL-137 (Standard)	Reference Standards Ras	Cancer
CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer .

HY-143463

AC-386	c-Met/HGFR	Cancer
AC-386 is a highly potent c-Met inhibitor with IC₅₀ value of 7.42 nM. AC-386 has antiproliferative activities against certain cancer cell lines. AC-386 can be used for researching anti-cancer resistance .

HY-172136

LSQ-28	HDAC	Cancer
LSQ-28 is an orally active HDAC3 inhibitor with an IC₅₀ of 42 nM, and exhibits potent anticancer, antiproliferative, antimigratory, anti-invasive, and antiwound healing activities. LSQ-28 can be utilized in cancer research .

HY-171165

JC168	Microtubule/Tubulin	Cancer
JC168 is a phenyl analog of peloruside and serves as a microtubule inhibitor, demonstrating antiproliferative and anticancer activities. JC168 promotes tubulin polymerization, thereby interfering with microtubule dynamics, and can be utilized in research related to microtubule-associated disorders .

HY-168842

PRMT5-IN-47	Histone Methyltransferase	Cancer
PRMT5-IN-47 (compound 20) is a potent, selectively and orally active, MTA cooperative PRMT5 inhibitor with an IC₅₀ value of 15 nM. PRMT5-IN-47 shows antiproliferative activity. PRMT5-IN-47 shows anticancer activity .

HY-N10354

27-Methyl withaferin A	Apoptosis	Cancer
27-Methyl withaferin A (comppund 26) is an apoptosis inducer with anticancer effects. 27-Methyl withaferin A shows antiproliferative effects against HeLa, A-549 and MCF-7 human tumor cell lines with IC₅₀ values of 3.2 μM, 4.2 μM and 1.4 μM, respectively .

HY-146465

Anticancer agent 60	Microtubule/Tubulin	Cancer
Anticancer agent 60 (compound 3h) has antiproliferative activity against human HepG2 cells (IC₅₀ = 4.13 μM) and presents antitumor efficacy in a human HepG2 xenograft mouse model .

HY-143253

Estrogen receptor antagonist 7	Estrogen Receptor/ERR	Cancer
Estrogen receptor antagonist 7 (compound 13) is a potent estrogen receptors (ER) antagonist. Estrogen receptor antagonist 7 has antiproliferative activity against breast and ovarian cancer cells. Anticancer and anti-uterotrophic activities .

HY-159512

EGFR kinase inhibitor 7	EGFR Apoptosis	Cancer
EGFR kinase inhibitor 7 (compound 18i) is an EGFR inhibitor (IC₅₀=42.3 nM) with anticancer activity. EGFR kinase inhibitor 7 has significant in vitro cytotoxicity and apoptosis induction ability. EGFR kinase inhibitor 7 has antiproliferative activity against human colon cancer cell line HCT116 and human non-small cell lung cancer cell line A549, with IC₅₀ values of 4.82 µM and 1.43 µM, respectively .

HY-175174

Antiproliferative agent-73	Glutaminase	Cancer
Antiproliferative agent-73 (Compound 7) is an antiproliferative agent. Antiproliferative agent-73 significantly inhibits proliferation of human cancer cells with excellent cytotoxicity. Antiproliferative agent-73 has potent anticancer activity with IC₅₀s of 15.20, 18.18, 20.20 and 13.23 μM for HepG2, MCF-7, HCT-116 and WI38 cells, respectively. Antiproliferative agent-73 can be used for cancers research, such as breast, colorectal and liver cancer .

Cat. No.	Product Name	Type

HY-110002

LFM-A13 1 Publications Verification	Biochemical Assay Reagents
LFM-A13 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC₅₀s of 2.5 μM, 10 μM and 61 μM. LFM-A13 has antiproliferative activity and anticancer activity. LFM-A13 can be used in cancer-related research

HY-W004121

4-Biphenylsulfonyl chloride

Biochemical Assay Reagents

4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the PI3K/Akt/mTOR pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC .

Cat. No.	Product Name	Target	Research Area

HY-P2228

Chlamydocin (purity≥70%)	HDAC Apoptosis	Cancer
Chlamydocin (purity≥70%), a fungal metabolite, is a highly potent HDAC inhibitor, with an IC₅₀ of 1.3 nM. Chlamydocin (purity≥70%) exhibits potent antiproliferative and anticancer activities. Chlamydocin (purity≥70%) induces apoptosis by activating caspase-3 .

HY-131923

DAPM	Notch	Cancer
DAPM is a Notch pathway inhibitor with anticancer activity and antiproliferative effects. DAPM effectively inhibits tubular adenoma development by inhibiting cell proliferation and inducing the expression of Krüppel-like factor 4 (KLF4) and p21 in human colon cancer cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1497

Plumbagin 3 Publications Verification 2-Methyljuglone	Quinones Monophenols Classification of Application Fields Anti-aging Plumbago zeylanica Linn. Phenols Plants Naphthalene Quinones Plumbaginaceae Disease Research Fields Source Classification Cancer	Others
Plumbagin (2-Methyljuglone) is a naphthoquinone isolated from Plumbago zeylanica, exhibits anticancer and antiproliferative activities .

HY-76316

Bergaptol 5-Hydroxypsoralen; 4-Hydroxybergapten	Structural Classification Monophenols other families Classification of Application Fields Coumarins Phenols Phenylpropanoids Plants Disease Research Fields Source Classification Cancer	Cytochrome P450
Bergaptol is an inhibitor of debenzylation of the CYP3A4 enzyme with an IC₅₀ of 24.92 μM. Recent studies have shown that it has anti-proliferative and anti-cancer properties .

HY-114489A

Haemanthamine	Infection Alkaloids Classification of Application Fields Neurological Disease Plants Sprekelia formosissima (L.) Herb. Isoquinoline Alkaloids Disease Research Fields Amaryllidaceae Source Classification	Apoptosis Influenza Virus Parasite
Haemanthamine is a crinine-type alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. Haemanthamine targets ribosomal that inhibits protein biosynthesis during the elongation stage of translation. Haemanthamine has pro-apoptotic, antioxidant, antiviral, antimalarial and anticonvulsant activities .

HY-126052

Gnetol	Stilbenes Classification of Application Fields Phenols Polyphenols Gnetaceae Metabolic Disease Plants Disease Research Fields Gnetum montanum Markgr. Source Classification	COX Tyrosinase HDAC
Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC₅₀ of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC₅₀ of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities .

HY-116035

Nimbolide 2 Publications Verification	Triterpenes Classification of Application Fields Terpenoids Azadirachta indica A. Juss. Plants Meliaceae Disease Research Fields Source Classification Cancer	Wnt NF-κB CDK Apoptosis
Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .

HY-N10503

Norartocarpetin	Flavonoids Flavones Plants Moraceae	Tyrosinase Ras Raf MAPKAPK2 (MK2) Apoptosis
Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC₅₀ value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC₅₀ value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells .

HY-119502

Camalexin 3 Publications Verification	Infection Alkaloids Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Camelina sativa (L.) Crantz Plants Brassicaceae Endogenous metabolite Disease Research Fields Indole Alkaloids Source Classification	Reactive Oxygen Species (ROS) Fungal Bacterial
Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production .

HY-N2510

Myristicin Myristicine	Simple Phenylpropanols Myristicaceae Phenylpropanoids Plants Myristica fragrans Houtt. Source Classification	5-HT Receptor EGFR ERK Apoptosis Bacterial
Myristicine is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc .

HY-N7085

Citropten 5,7-Dimethoxycoumarin; Limettin	Structural Classification Classification of Application Fields Rutaceae Coumarins Phenylpropanoids Plants Disease Research Fields Citrus medica Linn. var. sarcodactylis (Noot.) Swingle Cancer	Environmental Pollutants ERK p38 MAPK JNK
Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through heat shock protein-70, monoamine oxidase-A and inhibition of apoptosis .

HY-129476

L-Canaline	Infection other families Classification of Application Fields Amino acids Plants Endogenous metabolite Disease Research Fields Source Classification	Parasite Endogenous Metabolite
L-Canaline is a nonprotein amino acid stored in many leguminous plants. L-Canaline is a cytotoxic metabolite catalyzed by L-canavanine and its arginase. L-Canaline is a potent and irreversible inhibitor of ornithine aminotransferase. L-Canaline inhibits the growth of the malaria parasite *Plasmodium falciparum* with an IC₅₀ of 297 nM. L-Canaline has anticancer and antiproliferative effects .

HY-N7015

Zerumbone 2 Publications Verification	Infection Structural Classification Zingiber zerumbet Classification of Application Fields Terpenoids Sesquiterpenes Plants Disease Research Fields Source Classification Zingiberaceae	EBV Caspase Apoptosis Bacterial
Zerumbone is an orally active natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet. Zerumbone has anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity .

HY-18979

Lactimidomycin 1 Publications Verification	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Flavivirus Dengue Virus
Lactimidomycin is a glutarimide-containing compound isolated from Streptomyces. Lactimidomycin is a potent inhibitor of eukaryotic translation elongation. Lactimidomycin has a potent antiproliferative effect on tumor cell lines and selectively inhibit protein translation. Lactimidomycin inhibits protein synthesis with an IC₅₀ value of 37.82 nM. Lactimidomycin is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Anticancer and antiviral activities .

HY-N6064

Polygalacin D 3 Publications Verification	Triterpenes Classification of Application Fields Terpenoids Platycodon grandiflorus (Jacq.) A. DC. Campanulaceae Plants Disease Research Fields Cancer Source Classification	Apoptosis IAP
Polygalacin D (PGD) is a bioactive compound isolated from Platycodon grandiflorum with anticancer and anti-proliferative properties. PGD suppresses the expression of the IAP family of proteins including survivin, cIAP-1 and cIAP-2 and blocks the PI3K/Akt pathway by inhibiting the phosphorylation of GSK3β, Akt and the expression of PI3K. Polygalacin D induces apoptosis

HY-B1173

(+)-Camphor 1 Publications Verification D-(+)-Camphor; (1R)-(+)-Camphor	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Other Diseases Plants Lauraceae Cinnamomum camphora Disease Research Fields Source Classification	Environmental Pollutants Bacterial
(+)-Camphor (D-(+)-Camphor; (1R)-(+)-Camphor) is an isomer of Camphor. Camphor is an agonist of monoterpenoid transient receptor potential (TRP) channels (such as TRPV1, TRPV3, TRPM8) and an inhibitor of TRPA1 channels. Camphor's derivatives have multiple biological activities, including antibacterial, antiviral, antioxidant, analgesic and anticancer. Camphor can selectively activate cold-sensitive TRP channels and inhibit TRPA1-mediated nociceptive signals. Camphor stimulates the cold-sensing nerve endings in the skin and regulates the activity of ion channels to exert analgesic, anti-inflammatory and anti-itching effects. It also has anti-proliferative and anti-mutagenic activities on tumor cells, which may be related to inhibiting ribosome function or inducing cell apoptosis. Camphor can be absorbed through the skin and (+)-Camphor can be used in the study of muscle and joint pain and inflammation .

HY-N10544

δ-Cadinene (+)-δ-Cadinene	Structural Classification Terpenoids Labiatae Sesquiterpenes Plants Medicago sativa L.	Bacterial Parasite Fungal Apoptosis
δ-Cadinene ((+)-δ-Cadinene) is a sesquiterpene in essential oils. δ-Cadinene shows antiproliferative and pro-apoptotic effects on human ovary cancer (OVCAR-3) cells. δ-Cadinene has trichomonacidal, antimicrobial, antifungal and anticancer properties .

HY-N12540

Monogalactosyldiacylglycerol MGDG	Structural Classification other families Oplismenus burmannii Plants Lipid Source Classification	DNA/RNA Synthesis Apoptosis
Monogalactosyldiacylglycerol (MGDG) is a galactolipid with anti-inflammatory and anticancer activities, which is found in photosynthetic organisms. Monogalactosyldiacylglycerol is a potent DNA polymerase inhibitor with pro-apoptotic activity. Monogalactosyldiacylglycerol inhibits the synthesis of LPS (HY-D1056)-induced inflammation-related proteins (Ex-FABP, Avidin, Serum Amyloid A). Monogalactosyldiacylglycerol exerts an anti-proliferative effect on chicken articular chondrocytes . Monogalactosyldiacylglycerol can be used in research related to osteoarthritis, cancer and inflammatory diseases .

HY-N7015R

Zerumbone (Standard)	Structural Classification Natural Products Zingiber zerumbet Plants Source Classification Zingiberaceae	EBV Reference Standards Caspase Apoptosis Bacterial
Zerumbone (Standard) is the analytical standard of Zerumbone. This product is intended for research and analytical applications. Zerumbone is an orally active natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet. Zerumbone has anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity .

HY-N7523

Neoxanthin	Natural Products Classification of Application Fields Plants Food Research Agricultural Research Microorganisms other families Pigments Abscisic acid Phytohormone Disease Research Fields Source Classification Cancer	DNA/RNA Synthesis Apoptosis
Neoxanthin is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions .

HY-N7085R

Citropten (Standard) 5,7-Dimethoxycoumarin (Standard); Limettin (Standard)	Structural Classification Rutaceae Coumarins Phenylpropanoids Plants Citrus medica Linn. var. sarcodactylis (Noot.) Swingle	ERK JNK p38 MAPK Reference Standards
Citropten (Standard) is the analytical standard of Citropten. This product is intended for research and analytical applications. Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through heat shock protein-70, monoamine oxidase-A and inhibition of apoptosis .

HY-126423

Isorhamnetin 3-glucuronide Isorhamnetin 3-O-glucuronide	Flavonoids Flavones Endogenous metabolite Source Classification	Apoptosis
Isorhamnetin 3-glucuronide is a potent anticancer agent. Isorhamnetin 3-glucuronide shows anti-proliferative activity. Isorhamnetin 3-glucuronide induces Apoptosis and cell cycle arrest at S-phase .

HY-119502R

Camalexin (Standard)	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Camelina sativa (L.) Crantz Plants Brassicaceae Endogenous metabolite Indole Alkaloids Source Classification	Reference Standards Reactive Oxygen Species (ROS) Fungal Bacterial
Camalexin (Standard) is the analytical standard of Camalexin. This product is intended for research and analytical applications. Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production[1][2][3].

HY-N7640

Deoxylimonin	Triterpenes Microorganisms Classification of Application Fields Citrus paradisi Macf. Terpenoids Rutaceae Plants Disease Research Fields Inflammation/Immunology Source Classification	Others
Desoxylimonin is an orally active triterpenoid compound found from grapefruit seed. Desoxylimonin shows anti-proliferative activities to breast cancer cells. Desoxylimonin derivatives shows better anticancer, analgesic and anti-inflammatory activity than the lead compound .

HY-N2510R

Myristicin (Standard) Myristicine (Standard)	Structural Classification Simple Phenylpropanols Myristicaceae Phenylpropanoids Plants Myristica fragrans Houtt. Source Classification	5-HT Receptor EGFR ERK Reference Standards Apoptosis Bacterial
Myristicin (Standard) is the analytical standard of Myristicin. This product is intended for research and analytical applications. Myristicine is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc .

HY-114489B

Haemanthamine hydrochloride	Infection Alkaloids Neurological Disease Classification of Application Fields Plants Sprekelia formosissima (L.) Herb. Isoquinoline Alkaloids Disease Research Fields Amaryllidaceae Source Classification	Apoptosis Influenza Virus Parasite
Haemanthamine hydrochloride is a crinine-type alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. Haemanthamine hydrochloride targets ribosomal that inhibits protein biosynthesis during the elongation stage of translation. Haemanthamine hydrochloride has pro-apoptotic, antioxidant, antiviral, antimalarial and anticonvulsant activities .

HY-N15657

Geiparvarin	Terpenoids Rutaceae Diterpenoids Geijera parviflora Lindl. Plants Source Classification	Apoptosis COX Caspase Microtubule/Tubulin Monoamine Oxidase
Geiparvarin is an anticancer agent and an inhibitor of MAO-B (pIC₅₀ = 6.84 μM). Geiparvarin exerts anti-tumor effects by downregulating COX2 expression and inhibiting angiogenesis. Geiparvarin blocks the cell cycle at the G₁ phase and induces apoptosis of cancer cells. Geiparvarin has anti-microtubule activity and destroys the cytoskeleton to exert anti-proliferative effects. Geiparvarin has research significance for lung cancer, leukemia, and breast cancer .

HY-B1173R

(+)-Camphor (Standard) D-(+)-Camphor (Standard); (1R)-(+)-Camphor (Standard)	Structural Classification Other Monoterpenes Terpenoids Plants Lauraceae Cinnamomum camphora Source Classification	Reference Standards Bacterial
(+)-Camphor (Standard) is the analytical standard of (+)-Camphor. This product is intended for research and analytical applications. (+)-Camphor (D-(+)-Camphor; (1R)-(+)-Camphor) is an isomer of Camphor. Camphor is an agonist of monoterpenoid transient receptor potential (TRP) channels (such as TRPV1, TRPV3, TRPM8) and an inhibitor of TRPA1 channels. Camphor's derivatives have multiple biological activities, including antibacterial, antiviral, antioxidant, analgesic and anticancer. Camphor can selectively activate cold-sensitive TRP channels and inhibit TRPA1-mediated nociceptive signals. Camphor stimulates the cold-sensing nerve endings in the skin and regulates the activity of ion channels to exert analgesic, anti-inflammatory and anti-itching effects. It also has anti-proliferative and anti-mutagenic activities on tumor cells, which may be related to inhibiting ribosome function or inducing cell apoptosis. Camphor can be absorbed through the skin and (+)-Camphor can be used in the study of muscle and joint pain and inflammation .

HY-N7279

Epiaschantin (+)-Epiaschantin	other families Hernandia nymphaeifolia (C. Presl) Kubitzki Lignans Phenylpropanoids Plants Source Classification	Others
Epiaschantin is an anticancer agent. Epiaschantin shows antiproliferative activity .

HY-N1497R

Plumbagin (Standard) 2-Methyljuglone (Standard)	Quinones Structural Classification Monophenols Plumbago zeylanica Linn. Phenols Plants Naphthalene Quinones Plumbaginaceae Source Classification	Reference Standards Others
Plumbagin (Standard) is the analytical standard of Plumbagin. This product is intended for research and analytical applications. Plumbagin (2-Methyljuglone) is a naphthoquinone isolated from Plumbago zeylanica, exhibits anticancer and antiproliferative activities .

HY-N10392

(S)-Erypoegin K	Flavonoids Classification of Application Fields Leguminosae Erythrina poeppigiana Plants Disease Research Fields Isoflavones Cancer Source Classification	Apoptosis
(S)-Erypoegin K is a potent anticancer agent. (S)-Erypoegin K shows potent anti-proliferative activity against HL-60 cells. (S)-Erypoegin K induces apoptosis .

HY-N2858

Alpinumisoflavone acetate	Coumarins Phenylpropanoids Plants Millettia thonningii (Schumach. & Thonn.) Baker Source Classification Fabaceae	Apoptosis
Alpinumisoflavone acetate is a anticancer agent. Alpinumisoflavone acetate shows antiproliferative activity. Alpinumisoflavone acetate decreases the expression of phosphorylation of ERK1/2. Alpinumisoflavone acetate induces mitochondrial dysfunction and mitochondria-mediated Apoptosis. Alpinumisoflavone acetate has the potential for the research of HCC .

HY-N11050

Xerophilusin B	Terpenoids Labiatae Diterpenoids Plants Cosmos sulphureus Cav. Source Classification	Apoptosis
Xerophilusin B, an anticancer agent isolated from Isodon xerophilus, exhibits antiproliferative effects on esophageal squamous cell carcinoma (ESCC) cell lines, induces G2/M cell cycle arrest, and mediates apoptosis .

HY-76316R

Bergaptol (Standard) 5-Hydroxypsoralen (Standard); 4-Hydroxybergapten (Standard)	Structural Classification Monophenols other families Coumarins Phenols Phenylpropanoids Plants Source Classification	Reference Standards Cytochrome P450
Bergaptol (Standard) is the analytical standard of Bergaptol. This product is intended for research and analytical applications. Bergaptol is an inhibitor of debenzylation of the CYP3A4 enzyme with an IC₅₀ of 24.92 μM. Recent studies have shown that it has anti-proliferative and anti-cancer properties .

HY-N10355

27-TBDMS-4-Dehydrowithaferin A	Quinones Classification of Application Fields Benzene Quinones Withania somnifera Plants Solanaceae Disease Research Fields Steroids Cancer Source Classification	Apoptosis
27-TBDMS-4-Dehydrowithaferin A, a withaferin A derivative, exhibits potent antiproliferative effects on the tumor cells.27-TBDMS-4-Dehydrowithaferin A induces tumor cells apoptosis. 27-TBDMS-4-Dehydrowithaferin A is a anticancer agent .

HY-N10351

27-O-(tert-Butyldimethylsilyl)withaferin A	Classification of Application Fields Withania somnifera Plants Solanaceae Disease Research Fields Steroids Cancer Source Classification	Apoptosis
27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a), a natural withanolide, is an apoptosis inducer. 27-O-(tert-Butyldimethylsilyl)withaferin A shows antiproliferative activity against HeLa, A-549 and MCF-7 human cancer cell lines, and against normal Vero cells .

HY-N15346

Menominin B	Natural Products Microorganisms Source Classification	Others
Menominin B is a cyclic peptide found in the freshwater sponge-associated cyanobacterium Nostoc sp. with cytotoxic properties. Menominin B exhibits antiproliferative activity against the ovarian cancer cell line OVCAR3 (with IC₅₀ of 2.4 μM). Menominin B holds promise for research in the field of anticancer therapy .

HY-116035R

Nimbolide (Standard)	Triterpenes Structural Classification Terpenoids Azadirachta indica A. Juss. Plants Meliaceae Source Classification	Wnt NF-κB CDK Apoptosis Reference Standards
Nimbolide (Standard) is the analytical standard of Nimbolide. This product is intended for research and analytical applications. Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .

HY-N15424

Himachalol	Cedrus deodara (Roxburgh) G. Don Pinaceae Terpenoids Sesquiterpenes Plants Source Classification	Apoptosis Bcl-2 Family
Himachalol, a sesquiterpene, is an orally active antispasmodic and anticancer constituent found in the wood of Cedrus deodara. Himachalol has anti-proliferative activity against the melanoma cells, and induces apoptosis (decreases Bcl-2 level and increases Bax level). Himachalol has systemic hypotension and peripheral vasodilation effect. Himachalol inhibits Carbachol-induced spasm of the intestine. The LD₅₀ of Himachalol in mice is 265 mg/kg (p.o.) and 247 mg/kg (i.p.) .

HY-N3451

Isothymusin	Structural Classification Flavonoids Classification of Application Fields Flavones Labiatae Piliostigma thonningii (Schumach.) Milne-Redh. Plants Disease Research Fields Source Classification Cancer	Lipoxygenase
Isothymusin is a potent anti-oxidant agent. Isothymusin shows radical scavenging activities. Isothymusin shows anti-proliferative activities in cancer cell lines. Isothymusin inhibited the enzymes associated with the promotion stage of cancer, including cycloxygenase- 2 and lipoxygenase-5 .

HY-N12609

3β-Isodihydrocadambine	Structural Classification Alkaloids Rubiaceae Neolamarckia cadamba (Roxb.) Bosser Plants Indole Alkaloids Source Classification	Endogenous Metabolite
3β-Isodihydrocadambine, a derivative of cadambine, is obtained from the bark and leaves of Neolamarckia cadamba and possesses notable antimalarial, antiproliferative, antioxidant, anticancer, and anti-inflammatory properties.

HY-N19850

Mammea B/BD	Structural Classification Mammea americana L. Coumarins Phenylpropanoids Plants Calophyllaceae Source Classification	Biochemical Assay Reagents
Mammea B/BD is an anticancer antioxidant that can be isolated from the seeds of Mammea americana. Mammea B/BD exhibits antiproliferative effects on colon cancer cells. Mammea B/BD scavenges DPPH free radicals. Mammea B/BD can be used in colon cancer research .

HY-N15345

Menominin A	Microorganisms Cyclopeptides Source Classification	Others
Menominin A is a cyclic peptide identified from the freshwater sponge-associated cyanobacterium Nostoc sp., exhibiting cytotoxic properties. It displays antiproliferative activity against the ovarian cancer cell line OVCAR3, with an IC₅₀ value of 3.1 μM. Menominin A holds promise for research in the field of anticancer therapeutics .

HY-N13749

Juncatrin A	Structural Classification Juncaceae Phenols Polyphenols Juncus atratus Krocker Plants Source Classification	Others
Juncatrin A is a dihydrophenanthrene compound that can be naturally extracted from the whole plant methanol extract of Juncus atratus Krock. (a plant of the Juncaceae family, Juncus genus). Juncatrin A exhibits only weak antiproliferative activity against HeLa human cervical cancer cells (55.60% inhibition at 30 μM). Juncatrin A can be used in the research of anticancer natural drug precursors and active components of Juncus plants .

HY-Z11709

13-Hydroxy-alpha-tocopherol	Structural Classification Natural Products Garcinia kola Heckel Guttiferae Plants Source Classification	Endogenous Metabolite
13-Hydroxy-alpha-tocopherol is a fat-soluble vitamin E derivative and anticancer agent with antioxidant and antiproliferative activities. 13-Hydroxy-alpha-tocopherol scavenges peroxyl free radicals and protects polyunsaturated fatty acids from oxidative damage. 13-Hydroxy-alpha-tocopherol not only inhibits the growth of glioma cancer cells, but its deficiency is also closely associated with recurrent miscarriage, embryonic growth retardation and death. Clinical observations show that the expression of 13-Hydroxy-alpha-tocopherol is downregulated in the follicular fluid of patients with recurrent miscarriage. 13-Hydroxy-alpha-tocopherol has important application potential in the research of recurrent miscarriage and glioma .

Cat. No.	Product Name	Chemical Structure

HY-172733S

PRMT5-MTA-IN-3-d3

PRMT5-MTA-IN-3-d₃ (compound P22) is the deuterium labeled PRMT5-MTA-IN-3 (HY-172733). PRMT5-MTA-IN-3-d₃ is an orally active PRMT5-MTA inhibitor. PRMT5-MTA-IN-3-d₃ has antiproliferative effects on HTC116-MTAP del and wild type colorectal cancer HCT-116 cell lines, with IC₅₀ values of 6 nM and 961 nM, respectively. PRMT5-MTA-IN-3-d₃ has anticancer effects, especially for MTAP-deficient tumors, such as non-small cell lung cancer (NSCLC), pancreatic cancer .

HY-148185S

T01-1-d5
T01-1-d₅ (KL610023-d₅) is the deuterium labeled T01-1 (HY-148185). T01-1 is an anticancer agent (camptothecin derivative) with good anti-proliferative activity.

Cat. No.	Product Name		Classification

HY-19909

NRC-2694		Alkynes
NRC-2694 is an epidermal growth factor receptor (EGFR) antagonist with anti-cancer and anti-proliferative properties. NRC-2694 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

antiproliferative， anticancer

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products