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antituberculous

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Antibiotic (7) Apoptosis (2) Bacterial (15) c-Myc (1) COX (1) Drug Metabolite (1) Endogenous Metabolite (2) GSK-3 (1) Herbicide (2) Influenza Virus (1) Isotope-Labeled Compounds (2) NO Synthase (1) Photosystem II (2) Reactive Oxygen Species (ROS) (2) Reference Standards (4) Src (2) STAT (2) Stearoyl-CoA Desaturase (SCD) (2) Topoisomerase (1) β-catenin (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Infection (16) Inflammation/Immunology (10) Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-I0447

4-Aminosalicylic acid 1 Publications Verification	Antibiotic Bacterial	Infection Inflammation/Immunology
4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active .

HY-N0701

(-)-Asarinin 1 Publications Verification	Apoptosis Reactive Oxygen Species (ROS) STAT Src Stearoyl-CoA Desaturase (SCD) Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
(-)-Asarinin is a tetrahydrofurofurano lignan with various biological activities. (-)-Asarinin induces apoptosis in cancer cells. (-)-Asarinin promotes mitochondrial ROS accumulation, inhibits the STAT3 signaling pathway and induces apoptosis in precancerous cells. (-)-Asarinin is a Src family kinase inhibitor that suppresses mast cell activation. (-)-Asarinin is a non-competitive Δ5-desaturase inhibitor with a K_i of 0.28 mM. (-)-Asarinin possesses pain relief, anti-viral, anti-allergic and anti-tuberculous bacilli, and anti-tumor effects .

HY-I0447A

Sodium 4-aminosalicylate dihydrate 1 Publications Verification 4-Aminosalicylic acid sodium salt dihydrate	Antibiotic Bacterial	Infection Inflammation/Immunology
Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate) is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. Sodium 4-aminosalicylate dihydrate exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). Sodium 4-aminosalicylate dihydrate is orally active .

HY-W013186

Lansoprazole sulfide AG-1777	Drug Metabolite Bacterial	Inflammation/Immunology Cancer
Lansoprazole sulfide is an active metabolite of Lansoprazole by cytochrome P450, possesses anti-cancer activity. Lansoprazole sulfide is an anti-tuberculous agent, with an IC₅₀ of 0.59 µM for M. tb .

HY-W004570

5-Nitro-1,10-phenanthroline 5-NP	Endogenous Metabolite	Infection
5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells .

HY-W324882

Salinazid	Bacterial	Infection
Salinazid is an antituberculous compound .

HY-126771

Chrysomycin A Chr-A	Antibiotic Bacterial Akt GSK-3 β-catenin c-Myc	Infection Cancer
Chrysomycin A (Chr-A), an antibiotic, can be obtained from Streptomyces. Chrysomycin A exhibits antitumor and anti-tuberculous and MRSA activities. As for glioblastoma, Chrysomycin A inhibits the proliferation, migration, and invasion of cancer cells through the Akt/GSK-3β/β-catenin signaling pathway .

HY-N3848

Ermanin	Bacterial COX NO Synthase Influenza Virus	Infection Cardiovascular Disease Inflammation/Immunology
Ermanin is a flavonoid isolated from Tanacetum microphyllum. Ermanin potently inhibits iNOS, COX-2 activities, and inhibits platelet aggregation. Ermanin has anti-inflammatory, anti-tuberculous and anti-viral/bacterial properties .

HY-W131122

1,3,4-Oxadiazole	Bacterial	Others
1,3,4-Oxadiazoles are a class of synthetic compounds with important medicinal value, which show a variety of biological activities such as anticonvulsant, antidepressant, analgesic, anti-inflammatory, antiallergic, antipsychotic, antimicrobial, antituberculous, antitumor, and antiviral. 1,3,4-Oxadiazole derivatives need to be further developed .

HY-168849

Topoisomerase inhibitor 5	Topoisomerase Bacterial	Infection
Topoisomerase inhibitor 5 (compound 158) is a Bacterial Topoisomerase Inhibitor inhibitor with the lowest inhibitory concentration of 0.125 μg/mL. Topoisomerase inhibitor has antituberculous activity .

HY-22252

4-Aminosalicylic acid hemicalcium	Antibiotic Bacterial	Infection Inflammation/Immunology
4-Aminosalicylic acid hemicalcium is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid hemicalcium exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid hemicalcium is orally active .

HY-I0447R

4-Aminosalicylic acid (Standard)	Reference Standards Antibiotic Bacterial	Infection Inflammation/Immunology
4-Aminosalicylic acid (Standard) is the analytical standard of 4-Aminosalicylic acid. This product is intended for research and analytical applications. 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active .

HY-I0447AR

Sodium 4-aminosalicylate dihydrate (Standard) 4-Aminosalicylic acid sodium salt dihydrate (Standard)	Reference Standards Antibiotic Bacterial	Infection Inflammation/Immunology
Sodium 4-aminosalicylate (dihydrate) (Standard) is the analytical standard of Sodium 4-aminosalicylate (dihydrate). This product is intended for research and analytical applications. Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate) is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. Sodium 4-aminosalicylate dihydrate exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). Sodium 4-aminosalicylate dihydrate is orally active .

HY-N0701R

(-)-Asarinin (Standard)	Reference Standards Apoptosis Reactive Oxygen Species (ROS) STAT Src Stearoyl-CoA Desaturase (SCD) Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
(-)-Asarinin (Standard) is the analytical standard of (-)-Asarinin (HY-N0701). This product is intended for research and analytical applications. (-)-Asarinin is a tetrahydrofurofurano lignan with various biological activities. (-)-Asarinin induces apoptosis in cancer cells. (-)-Asarinin promotes mitochondrial ROS accumulation, inhibits the STAT3 signaling pathway and induces apoptosis in precancerous cells. (-)-Asarinin is a Src family kinase inhibitor that suppresses mast cell activation. (-)-Asarinin is a non-competitive Δ5-desaturase inhibitor with a K_i of 0.28 mM. (-)-Asarinin possesses pain relief, anti-viral, anti-allergic and anti-tuberculous bacilli, and anti-tumor effects.

HY-W778649

Sarmentine-d8	Isotope-Labeled Compounds Herbicide Photosystem II	Others
Sarmentine-d₈ is the deuterium labeled Sarmentine. Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC₅₀ of 3.0 μM and a K_i of 1.5 μM against spinach, an IC₅₀ of 1.72 μM against wild-type Amaranthus retroflexus, and an IC₅₀ of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the Q_B binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC₅₀ of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities .

HY-I0447S

4-Aminosalicylic acid-d6	Isotope-Labeled Compounds Antibiotic Bacterial	Infection Inflammation/Immunology
4-Aminosalicylic acid-d₆ is the deuterium labeled 4-Aminosalicylic acid (HY-I0447). 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active .

HY-180854

Antitubercular agent-55	Bacterial	Infection
Antitubercular agent-55 (Compound 2e) is an anti-tuberculous agent. Antitubercular agent-55 exhibits significant inhibitory activity against the standard strain of Mycobacterium tuberculosis H37Rv and also has moderate inhibitory activity against multidrug-resistant TB (MDR-TB). Antitubercular agent-55 has a strong affinity for the key enzyme InhA involved in the biosynthesis of mycotic acids. Antitubercular agent-55 can be used for research on tuberculosis infection caused by Mycobacterium tuberculosis.

HY-W004570R

5-Nitro-1,10-phenanthroline (Standard) 5-NP (Standard)	Endogenous Metabolite Reference Standards	Infection
5-Nitro-1,10-phenanthroline (Standard) (5-NP (Standard)) is the analytical standard of 5-Nitro-1,10-phenanthroline (HY-W004570). This product is intended for research and analytical applications. 5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells .

HY-W099725

Sarmentine	Herbicide Photosystem II	Cardiovascular Disease Infection
Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC₅₀ of 3.0 μM and a K_i of 1.5 μM against spinach, an IC₅₀ of 1.72 μM against wild-type Amaranthus retroflexus, and an IC₅₀ of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the Q_B binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC₅₀ of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0701

(-)-Asarinin 1 Publications Verification	Asarum sieboldii Miq. Classification of Application Fields Lignans Phenylpropanoids Plants Aristolochiaceae Disease Research Fields Source Classification Cancer	Apoptosis Reactive Oxygen Species (ROS) STAT Src Stearoyl-CoA Desaturase (SCD) Bacterial
(-)-Asarinin is a tetrahydrofurofurano lignan with various biological activities. (-)-Asarinin induces apoptosis in cancer cells. (-)-Asarinin promotes mitochondrial ROS accumulation, inhibits the STAT3 signaling pathway and induces apoptosis in precancerous cells. (-)-Asarinin is a Src family kinase inhibitor that suppresses mast cell activation. (-)-Asarinin is a non-competitive Δ5-desaturase inhibitor with a K_i of 0.28 mM. (-)-Asarinin possesses pain relief, anti-viral, anti-allergic and anti-tuberculous bacilli, and anti-tumor effects .

HY-W004570

5-Nitro-1,10-phenanthroline 5-NP	Infection Alkaloids Classification of Application Fields Pyridine Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells .

HY-N3848

Ermanin	Cardiovascular Disease Flavonols Flavonoids Classification of Application Fields Phenols Polyphenols Plants Curcuma phaeocaulis Valeton Inflammation/Immunology Disease Research Fields Source Classification Zingiberaceae	Bacterial COX NO Synthase Influenza Virus
Ermanin is a flavonoid isolated from Tanacetum microphyllum. Ermanin potently inhibits iNOS, COX-2 activities, and inhibits platelet aggregation. Ermanin has anti-inflammatory, anti-tuberculous and anti-viral/bacterial properties .

HY-N0701R

(-)-Asarinin (Standard)	Asarum sieboldii Miq. Structural Classification Lignans Phenylpropanoids Plants Aristolochiaceae Source Classification	Reference Standards Apoptosis Reactive Oxygen Species (ROS) STAT Src Stearoyl-CoA Desaturase (SCD) Bacterial
(-)-Asarinin (Standard) is the analytical standard of (-)-Asarinin (HY-N0701). This product is intended for research and analytical applications. (-)-Asarinin is a tetrahydrofurofurano lignan with various biological activities. (-)-Asarinin induces apoptosis in cancer cells. (-)-Asarinin promotes mitochondrial ROS accumulation, inhibits the STAT3 signaling pathway and induces apoptosis in precancerous cells. (-)-Asarinin is a Src family kinase inhibitor that suppresses mast cell activation. (-)-Asarinin is a non-competitive Δ5-desaturase inhibitor with a K_i of 0.28 mM. (-)-Asarinin possesses pain relief, anti-viral, anti-allergic and anti-tuberculous bacilli, and anti-tumor effects.

HY-W004570R

5-Nitro-1,10-phenanthroline (Standard) 5-NP (Standard)	Structural Classification Alkaloids Pyridine Alkaloids Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
5-Nitro-1,10-phenanthroline (Standard) (5-NP (Standard)) is the analytical standard of 5-Nitro-1,10-phenanthroline (HY-W004570). This product is intended for research and analytical applications. 5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells .

HY-W099725

Sarmentine	Piper longum Linn. Structural Classification Alkaloids Pyrrole Alkaloids Piperaceae Plants Source Classification	Herbicide Photosystem II
Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC₅₀ of 3.0 μM and a K_i of 1.5 μM against spinach, an IC₅₀ of 1.72 μM against wild-type Amaranthus retroflexus, and an IC₅₀ of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the Q_B binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC₅₀ of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities .

Cat. No.	Product Name	Chemical Structure

HY-W778649

Sarmentine-d8
Sarmentine-d₈ is the deuterium labeled Sarmentine. Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC₅₀ of 3.0 μM and a K_i of 1.5 μM against spinach, an IC₅₀ of 1.72 μM against wild-type Amaranthus retroflexus, and an IC₅₀ of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the Q_B binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC₅₀ of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities .

Sarmentine-d8

Sarmentine-d₈ is the deuterium labeled Sarmentine. Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC₅₀ of 3.0 μM and a K_i of 1.5 μM against spinach, an IC₅₀ of 1.72 μM against wild-type Amaranthus retroflexus, and an IC₅₀ of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the Q_B binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC₅₀ of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities .

HY-I0447S

4-Aminosalicylic acid-d6
4-Aminosalicylic acid-d₆ is the deuterium labeled 4-Aminosalicylic acid (HY-I0447). 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active .

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antituberculous

Inhibitors & Agonists

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Isotope-Labeled Compounds

Natural
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