20 Results for "

antituberculous

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "antituberculous" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-I0447
CAS No.: 65-49-6
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Inflammation/Immunology

4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active .
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1 Cited Publications
Cat. No.: HY-N0701
CAS No.: 133-04-0
(-)-Asarinin is a tetrahydrofurofurano lignan with various biological activities. (-)-Asarinin induces apoptosis in cancer cells. (-)-Asarinin promotes mitochondrial ROS accumulation, inhibits the STAT3 signaling pathway and induces apoptosis in precancerous cells. (-)-Asarinin is a Src family kinase inhibitor that suppresses mast cell activation. (-)-Asarinin is a non-competitive Δ5-desaturase inhibitor with a Ki of 0.28 mM. (-)-Asarinin possesses pain relief, anti-viral, anti-allergic and anti-tuberculous bacilli, and anti-tumor effects .
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1 Cited Publications
Cat. No.: HY-I0447A
CAS No.: 6018-19-5
Synonyms: 4-Aminosalicylic acid sodium salt dihydrate
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Inflammation/Immunology

Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate) is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. Sodium 4-aminosalicylate dihydrate exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). Sodium 4-aminosalicylate dihydrate is orally active .
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1
1 Cited Publications
Cat. No.: HY-76210
CAS No.: 34604-60-9
Research Areas:  

Infection

5-Hydroxypyrazine-2-Carboxylic Acid is a dibasic acid and also a urinary metabolite of coffee-derived 2-methylpyrazine (HY-W067358). 5-Hydroxypyrazine-2-Carboxylic Acid serves as an intermediate in the production of anti-tuberculosis reagents. It can be used in research related to tuberculosis [1] [2].
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Cat. No.: HY-W013186
CAS No.: 103577-40-8
Synonyms: AG-1777
Research Areas:  

Inflammation/Immunology Cancer

Lansoprazole sulfide is an active metabolite of Lansoprazole by cytochrome P450, possesses anti-cancer activity. Lansoprazole sulfide is an anti-tuberculous agent, with an IC50 of 0.59 µM for M. tb .
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Cat. No.: HY-W004570
CAS No.: 4199-88-6
Synonyms: 5-NP
5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells .
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Cat. No.: HY-W324882
CAS No.: 495-84-1
Target:  

Bacterial

Research Areas:  

Infection

Salinazid is an antituberculous compound .
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Cat. No.: HY-126771
CAS No.: 82196-88-1
Synonyms: Chr-A
Research Areas:  

Infection Cancer

Chrysomycin A (Chr-A), an antibiotic, can be obtained from Streptomyces. Chrysomycin A exhibits antitumor and anti-tuberculous and MRSA activities. As for glioblastoma, Chrysomycin A inhibits the proliferation, migration, and invasion of cancer cells through the Akt/GSK-3β/β-catenin signaling pathway .
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Cat. No.: HY-N3848
CAS No.: 20869-95-8
Ermanin is a flavonoid isolated from Tanacetum microphyllum. Ermanin potently inhibits iNOS, COX-2 activities, and inhibits platelet aggregation. Ermanin has anti-inflammatory, anti-tuberculous and anti-viral/bacterial properties .
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Cat. No.: HY-W131122
CAS No.: 288-99-3
Target:  

Bacterial

Research Areas:  

Others

1,3,4-Oxadiazoles are a class of synthetic compounds with important medicinal value, which show a variety of biological activities such as anticonvulsant, antidepressant, analgesic, anti-inflammatory, antiallergic, antipsychotic, antimicrobial, antituberculous, antitumor, and antiviral. 1,3,4-Oxadiazole derivatives need to be further developed .
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Cat. No.: HY-168849
CAS No.: 2758889-92-6
Target:  

Topoisomerase Bacterial

Research Areas:  

Infection

Topoisomerase inhibitor 5 (compound 158) is a Bacterial Topoisomerase Inhibitor inhibitor with the lowest inhibitory concentration of 0.125 μg/mL. Topoisomerase inhibitor has antituberculous activity .
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Cat. No.: HY-22252
CAS No.: 133-15-3
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Inflammation/Immunology

4-Aminosalicylic acid hemicalcium is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid hemicalcium exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid hemicalcium is orally active .
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Cat. No.: HY-I0447R
CAS No.: 65-49-6
4-Aminosalicylic acid (Standard) is the analytical standard of 4-Aminosalicylic acid. This product is intended for research and analytical applications. 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active .
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Cat. No.: HY-I0447AR
CAS No.: 6018-19-5
Synonyms: 4-Aminosalicylic acid sodium salt dihydrate (Standard)
Sodium 4-aminosalicylate (dihydrate) (Standard) is the analytical standard of Sodium 4-aminosalicylate (dihydrate). This product is intended for research and analytical applications. Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate) is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. Sodium 4-aminosalicylate dihydrate exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). Sodium 4-aminosalicylate dihydrate is orally active .
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Cat. No.: HY-N0701R
CAS No.: 133-04-0
(-)-Asarinin (Standard) is the analytical standard of (-)-Asarinin (HY-N0701). This product is intended for research and analytical applications. (-)-Asarinin is a tetrahydrofurofurano lignan with various biological activities. (-)-Asarinin induces apoptosis in cancer cells. (-)-Asarinin promotes mitochondrial ROS accumulation, inhibits the STAT3 signaling pathway and induces apoptosis in precancerous cells. (-)-Asarinin is a Src family kinase inhibitor that suppresses mast cell activation. (-)-Asarinin is a non-competitive Δ5-desaturase inhibitor with a Ki of 0.28 mM. (-)-Asarinin possesses pain relief, anti-viral, anti-allergic and anti-tuberculous bacilli, and anti-tumor effects.
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Cat. No.: HY-W778649
CAS No.: 1795136-21-8
Sarmentine-d8 is the deuterium labeled Sarmentine. Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC50 of 3.0 μM and a Ki of 1.5 μM against spinach, an IC50 of 1.72 μM against wild-type Amaranthus retroflexus, and an IC50 of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the QB binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC50 of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities .
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Cat. No.: HY-I0447S
4-Aminosalicylic acid-d6 is the deuterium labeled 4-Aminosalicylic acid (HY-I0447). 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active .
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Cat. No.: HY-180854
Target:  

Bacterial

Research Areas:  

Infection

Antitubercular agent-55 (Compound 2e) is an anti-tuberculous agent. Antitubercular agent-55 exhibits significant inhibitory activity against the standard strain of Mycobacterium tuberculosis H37Rv and also has moderate inhibitory activity against multidrug-resistant TB (MDR-TB). Antitubercular agent-55 has a strong affinity for the key enzyme InhA involved in the biosynthesis of mycotic acids. Antitubercular agent-55 can be used for research on tuberculosis infection caused by Mycobacterium tuberculosis.
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Cat. No.: HY-W004570R
CAS No.: 4199-88-6
Synonyms: 5-NP (Standard)
5-Nitro-1,10-phenanthroline (Standard) (5-NP (Standard)) is the analytical standard of 5-Nitro-1,10-phenanthroline (HY-W004570). This product is intended for research and analytical applications. 5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells .
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Cat. No.: HY-W099725
CAS No.: 78910-33-5
Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC50 of 3.0 μM and a Ki of 1.5 μM against spinach, an IC50 of 1.72 μM against wild-type Amaranthus retroflexus, and an IC50 of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the QB binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC50 of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities .
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