2 Results for "

complement-activating protein

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "complement-activating protein" in MCE Product Catalog:

Cat. No.: HY-NP004
Synonyms: CVF
Cobra Venom Factor (CVF) is a selective activator targeting complement components C3, C5, and factor B in the complement system. After binding to factor B, Cobra Venom Factor is cleaved by factor D, forming a stable C3/C5 convertase resistant to regulatory proteins H and I. This continuously hydrolyzes C3 and C5, depleting serum complement while inducing neutrophil migration, vascular leakage, and increased TNF-α levels. Cobra Venom Factor can be used to deplete complement and mimic complement activation-related pathological states, and is applied in animal models of complement-mediated diseases such as acute respiratory distress syndrome (ARDS), sepsis, and shock. Cobra Venom Factor can be isolated from the venom of cobras (e.g., Naja atra, Naja melanoleuca, Naja kaouthia, etc.) .
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Cat. No.: HY-P704127
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MASP3; MASP1; CRARF1; RaRF; Mannan-binding lectin serine protease 1; complement factor MASP-3; complement-activating component of Ra-reactive factor; Mannose-binding lectin-associated serine protease 1 (MASP-1); Mannose-binding protein-associated serine protease; Ra-reactive factor serine protease p100 (RaRF); Serine protease 5
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