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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
cytotoxic T lymphocyte (CTL)
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "cytotoxic T lymphocyte (CTL)" in MCE Product Catalog:
2
2
2 Cited Publications
Cat. No.: HY-P76377
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GZMA; cytotoxic T-lymphocyte Proteinase 1; Prev. CTLA3; Granzyme 1; Prev. HFSP; H Factor; CTL Tryptase; HF; Fragmentin-1; Granzyme A (cytotoxic T-lymphocyte-Associated Serine Esterase-3; Hanukah Factor Serine Protease); Granzyme A (Granzyme 1, cytotoxic T
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-160768
Target:
Research Areas:
OTUB2-IN-1, a specific inhibitor of OTUB2 (KD: ~12 μM), reduces PD-L1 protein expression in tumor cells and inhibits tumor growth by promoting robust intra-tumor infiltration of cytotoxic T lymphocytes (CTL) .
Cat. No.: HY-163028
CAS No.: 459789-75-4
ML-T7 is a potent Tim-3 inhibitor. ML-T7 blocks Tim-3 interactions with PtdSer and CEACAM1. ML-T7 not only enhances the antitumor activity of adoptive transfer therapy with cytotoxic T lymphocytes (CTLs) and CAR T cells but also increases the effector function of T cell. ML-T7 promotes NK cells’ killing activity against tumor cells and DC antigen-presenting capacity. ML-T7 directly exerts antitumor efficacy in preclinical tumor models either alone or in combination with Nivolumab (HY-P9903A). ML-T7 can be used for tumor immunotherapy research .
Cat. No.: HY-172240
CAS No.: 1418305-55-1
Synonyms: TU2218 free base
Research Areas:
Tosposertib (TU2218 free base) is an ALK5/VEGFR2 dual inhibitor (IC50 = 1.2 nM/4.9 nM). Tosposertib directly restores the activity of damaged cytotoxic T lymphocytes (CTLs) and natural killer cells inhibited by TGFβ and suppresses the activity and viability of regulatory T cells. Tosposertib can be used for the study of melanoma and colon cancer .
Cat. No.: HY-P1907
CAS No.: 151812-18-9
Cat. No.: HY-P990795
Target:
Research Areas:
Cat. No.: HY-P0277
CAS No.: 168635-85-6
Synonyms: CEA peptide
Cat. No.: HY-P5470
CAS No.: 152274-91-4
Research Areas:
CAMK1D-IN-1 (compound I) is an inhibitor of CAMK1D, targeting cytotoxic T lymphocyte (CTL)-resistant tumor cells. CAMK1D impairs CTL-induced death receptor signaling and apoptosis by inhibiting caspases, making it a key and effective target for PD-L1-refractory tumors .
Cat. No.: HY-P1827
CAS No.: 219312-69-3
Target:
Research Areas:
Cat. No.: HY-P2495A
Target:
Research Areas:
Cat. No.: HY-P3742
CAS No.: 170294-35-6
Target:
Research Areas:
Cat. No.: HY-106374
CAS No.: 673478-49-4
Cat. No.: HY-P1855
CAS No.: 160790-21-6
Cat. No.: HY-P2495
CAS No.: 2648610-97-1
Target:
Research Areas:
Cat. No.: HY-P1881
CAS No.: 160040-04-0
Cat. No.: HY-P990928
CAS No.: 2839556-21-5
Synonyms: APVO-436
Target:
Research Areas:
Cat. No.: HY-P10593
CAS No.: 126779-14-4
Research Areas:
Cat. No.: HY-105039
CAS No.: 181477-43-0
Synonyms: G209-2M; GP100:209-217(210M); MPS-22
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
