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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
deoxynucleoside
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "deoxynucleoside" in MCE Product Catalog:
16
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
11
11 Cited Publications
Research Areas:
IMT1 is a first-in-class specific and noncompetitive human mitochondrial RNA polymerase (POLRMT) inhibitor. IMT1 causes a conformational change of POLRMT, which blocks substrate binding and transcription in a dose-dependent way in vitro. IMT1 reduces deoxynucleoside triphosphate levels and citric acid cycle intermediates, resulting in a marked depletion of cellular amino acid levels. IMT1 has the potential for mitochondrial transcription disorders related diseases .
1
1 Cited Publications
Cat. No.: HY-D1668
Cat. No.: HY-W012282
CAS No.: 7057-27-4
3′-Deoxyuridine is a 3'-deoxynucleoside analog and a 2',3'-dideoxynucleoside. 3′-Deoxyuridine does not inhibit the replication of HCV-like RNA templates or luciferase levels in human cells at the tested concentrations. 3′-Deoxyuridine serves as a substrate for microbial dideoxyribosylation reactions to generate various 2',3'-dideoxynucleosides, but cannot be converted into 2',3'-dideoxycytidine by resting E. coli AJ 2595 cells. 3′-Deoxyuridine can be formed by the deamination of 3'-deoxycytidine by E. coli BM-11 cytidine deaminase, and can also undergo phosphorolytic cleavage to produce uracil and the corresponding pentose phosphate. 3′-Deoxyuridine has been used in research related to HCV and other relevant fields .
Cat. No.: HY-W048490
CAS No.: 166247-63-8
Cat. No.: HY-W013715B
CAS No.: 27821-54-1
Synonyms: dTTP trisodium,100 mM Solution,PCR Grade
Cat. No.: HY-W077279
CAS No.: 100898-63-3
Synonyms: N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
Cat. No.: HY-P5443
CAS No.: 224569-84-0
Cat. No.: HY-137618B
CAS No.: 80902-29-0
Rp-dGTPαS is the nucleotide substrate of SAMHD1 and is one of the enantiomers of the dNTPαS nucleotide. SAMHD1 is an essential regulator of cellular dNTPs that limits virus (HIV-1, etc.) replication in the CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex catalyzes the hydrolysis of Rp-dGTPαS into 2'-deoxynucleosides and triphosphates .
Cat. No.: HY-183641
CAS No.: 1377950-66-7
Target:
Research Areas:
5'-O-DMTr-N,N-Dimethylacetamide-dA-3'-CE phosphoramidite is a Phosphoramidite derivative. 5'-O-DMTr-N,N-Dimethylacetamide-dA-3'-CE phosphoramidite can be used in studies related to the introduction of N-alkyl nucleosides into DNA oligonucleotides .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
