22 Results for "

ecdysone

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "ecdysone" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-N0179
CAS. Nr.: 3604-87-3
Synonyms: α-ecdysone
Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979) .
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14
14 Publications Verification
Art. -Nr.: HY-N6979
CAS. Nr.: 5289-74-7
Synonyms: 20-Hydroxyecdysone
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
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1
1 Cited Publications
Art. -Nr.: HY-117386
CAS. Nr.: 161050-58-4
Reinheit:  98.10%
Forschungsgebiete:  

Infection

Methoxyfenozide is an orally active insecticide belonging to the diacylhydrazine and non-steroidal ecdysone agonist classes, which can interfere with the growth and development of insects. Methoxyfenozide has ovicidal and insecticidal activities against phytophagous pests .
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1
1 Cited Publications
Art. -Nr.: HY-N1534
CAS. Nr.: 13408-56-5
Synonyms: 25-Deoxyecdysterone
Ponasterone A (25-Deoxyecdysterone), an ecdysteroid, has strong affinity for the ecdysone receptor. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly .
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1
1 Cited Publications
Art. -Nr.: HY-17533
CAS. Nr.: 143807-66-3
Synonyms: ANS118
Target:  

Insecticide

Forschungsgebiete:  

Infection

Chromafenozide is a potent partial ecdysone receptor agonist and dibenzoylhydrazine insecticide. Chromafenozide inhibits insect feeding and causes the insect to molt prematurely, leading to death. Chromafenozide shows antagonistic activity against 20-HE. Chromafenozide shows high toxicity against Spodoptera exigua and Spodoptera littoralis .
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Art. -Nr.: HY-B1331
CAS. Nr.: 66215-27-8
Synonyms: Cyromazin; CGA-72662
Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats .
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Art. -Nr.: HY-16785
CAS. Nr.: 1093130-72-3
Synonyms: INXN-1001; RG-115932
Target:  

Interleukin Related

Forschungsgebiete:  

Inflammation/Immunology Cancer

Veledimex (INXN-1001), a synthetic analog of the insect molting hormone ecdysone, is an orally active activator ligand for a proprietary gene therapy promoter system. Veledimex can be used to activate certain genes using the ecdysone receptor (EcR)-based inducible gene regulation system, the RheoSwitch Therapeutic System (RTS). Veledimex can cross blood-brain barrier (BBB) in both orthotopic GL-261 mice and cynomolgus monkeys .
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Art. -Nr.: HY-B2054
CAS. Nr.: 112410-23-8
Forschungsgebiete:  

Cancer

Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
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Art. -Nr.: HY-103273
CAS. Nr.: 38778-30-2
Reinheit:  98.90%
Muristerone A is a phytoecdysteroid analog of ecdysone and a potent agonist of ecdysteroid receptor with a Kd of 1 nM .
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Art. -Nr.: HY-129671
CAS. Nr.: 18069-14-2
Reinheit:  98.60%
Synonyms: 5β-Hydroxyecdysterone
Target:  

Parasite Fungal

Forschungsgebiete:  

Infection

Polypodine B is a natural ecdysone ester isolated from the bark of Dacrydium intermedium. Polypodine B significantly inhibits the activity of Acanthamoeba castellani. Polypodine B has moderate antifungal activity. Polypodine B can be used for research on parasitic diseases and fungal infections .
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Art. -Nr.: HY-114636
CAS. Nr.: 162326-49-0
Target:  

Insecticide

Forschungsgebiete:  

Others

RG-102240 is a ligand for insect ecdysone receptor (EcR), with IC50 of 85 and 13 nM, in wildtype G:CfE(DEF) and its A110P mutant. RG-102240 induces the reporter gene activity of wild-type CfEcR and A110P mutant .
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Art. -Nr.: HY-117386S
CAS. Nr.: 2469014-53-5
Methoxyfenozide-d9 is the deuterium labeled Methoxyfenozide (HY-117386). Methoxyfenozide is an orally active insecticide belonging to the diacylhydrazine and non-steroidal ecdysone agonist classes, which can interfere with the growth and development of insects. Methoxyfenozide has ovicidal and insecticidal activities against phytophagous pests .
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Art. -Nr.: HY-W750355
CAS. Nr.: 99399-65-2
Azadirachtin D is an insect growth regulator targeting ecdysone receptor (EcR) in insects. Azadirachtin D blocks the 20-hydroxyecdysone signaling pathway, leading to developmental arrest or death in insects. Azadirachtin D is promising for research of agricultural pests .
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Art. -Nr.: HY-B2054S
CAS. Nr.: 2469006-89-9
Tebufenozide-d9 is the deuterium labeled Tebufenozide (HY-B2054). Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
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Art. -Nr.: HY-117386R
CAS. Nr.: 161050-58-4
Forschungsgebiete:  

Infection

Methoxyfenozide (Standard) is the analytical standard of Methoxyfenozide (HY-117386). This product is intended for research and analytical applications. Methoxyfenozide is an orally active insecticide belonging to the diacylhydrazine and non-steroidal ecdysone agonist classes, which can interfere with the growth and development of insects. Methoxyfenozide has ovicidal and insecticidal activities against phytophagous pests.
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Art. -Nr.: HY-B2054R
CAS. Nr.: 112410-23-8
Forschungsgebiete:  

Cancer

Tebufenozide (Standard) is the analytical standard of Tebufenozide (HY-B2054). This product is intended for research and analytical applications. Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
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Art. -Nr.: HY-N16479
CAS. Nr.: 134788-16-2
Azadirachtin I is an insecticide targeting insect growth and development-related pathways (e.g., ecdysone signaling pathway, chitin synthesis pathway). Azadirachtin I inhibits chitin synthesis and disrupting intestinal function by interfering with the growth and development processes of insect larvae such as molting and pupation, increasing insect mortality and reducing adult fecundity. Azadirachtin I is promising for research of agricultural pests, such as Lepidoptera, Coleoptera .
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Art. -Nr.: HY-17533R
CAS. Nr.: 143807-66-3
Synonyms: ANS118 (Standard)
Forschungsgebiete:  

Infection

Chromafenozide (Standard) is the analytical standard of Chromafenozide. This product is intended for research and analytical applications. Chromafenozide is a potent partial ecdysone receptor agonist and dibenzoylhydrazine insecticide. Chromafenozide inhibits insect feeding and causes the insect to molt prematurely, leading to death. Chromafenozide shows antagonistic activity against 20-HE. Chromafenozide shows high toxicity against Spodoptera exigua and Spodoptera littoralis .
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Art. -Nr.: HY-N6979R
CAS. Nr.: 5289-74-7
Synonyms: 20-Hydroxyecdysone (Standard)
Crustecdysone (Standard) is the analytical standard of Crustecdysone. This product is intended for research and analytical applications. Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
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Art. -Nr.: HY-B1331R
CAS. Nr.: 66215-27-8
Synonyms: Cyromazin (Standard); CGA-72662 (Standard)
Cyromazine (Standard) is the analytical standard of Cyromazine. This product is intended for research and analytical applications. Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats .
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