26 Results for "

ecdysone

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "ecdysone" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-N6979
CAS No.: 5289-74-7
Synonyms: 20-Hydroxyecdysone
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
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1 Cited Publications
Cat. No.: HY-N0179
CAS No.: 3604-87-3
Synonyms: α-ecdysone
Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979) .
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1 Cited Publications
Cat. No.: HY-117386
CAS No.: 161050-58-4
Purity:  98.10%
Research Areas:  

Infection

Methoxyfenozide is an orally active insecticide belonging to the diacylhydrazine and non-steroidal ecdysone agonist classes, which can interfere with the growth and development of insects. Methoxyfenozide has ovicidal and insecticidal activities against phytophagous pests .
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1 Cited Publications
Cat. No.: HY-N1534
CAS No.: 13408-56-5
Synonyms: 25-Deoxyecdysterone
Ponasterone A (25-Deoxyecdysterone), an ecdysteroid, has strong affinity for the ecdysone receptor. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly .
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1 Cited Publications
Cat. No.: HY-17533
CAS No.: 143807-66-3
Synonyms: ANS118
Target:  

Insecticide

Research Areas:  

Infection

Chromafenozide is a potent partial ecdysone receptor agonist and dibenzoylhydrazine insecticide. Chromafenozide inhibits insect feeding and causes the insect to molt prematurely, leading to death. Chromafenozide shows antagonistic activity against 20-HE. Chromafenozide shows high toxicity against Spodoptera exigua and Spodoptera littoralis .
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Cat. No.: HY-B1331
CAS No.: 66215-27-8
Synonyms: Cyromazin; CGA-72662
Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats .
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Cat. No.: HY-B2054
CAS No.: 112410-23-8
Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
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Cat. No.: HY-16785
CAS No.: 1093130-72-3
Synonyms: INXN-1001; RG-115932
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Veledimex (INXN-1001), a synthetic analog of the insect molting hormone ecdysone, is an orally active activator ligand for a proprietary gene therapy promoter system. Veledimex can be used to activate certain genes using the ecdysone receptor (EcR)-based inducible gene regulation system, the RheoSwitch Therapeutic System (RTS). Veledimex can cross blood-brain barrier (BBB) in both orthotopic GL-261 mice and cynomolgus monkeys .
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Cat. No.: HY-103273
CAS No.: 38778-30-2
Purity:  98.90%
Muristerone A is a phytoecdysteroid analog of ecdysone and a potent agonist of ecdysteroid receptor with a Kd of 1 nM .
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Cat. No.: HY-113890
CAS No.: 112226-61-6
Purity:  99.42%
Synonyms: RH-0345
Research Areas:  

Others

Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone .
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Cat. No.: HY-129671
CAS No.: 18069-14-2
Purity:  98.60%
Synonyms: 5β-Hydroxyecdysterone
Target:  

Parasite Fungal

Research Areas:  

Infection

Polypodine B is a natural ecdysone ester isolated from the bark of Dacrydium intermedium. Polypodine B significantly inhibits the activity of Acanthamoeba castellani. Polypodine B has moderate antifungal activity. Polypodine B can be used for research on parasitic diseases and fungal infections .
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Cat. No.: HY-W339331
CAS No.: 272451-65-7
Synonyms: NNI-0001
Flubendiamide (NNI-0001) is an orally active phthalic diamide insecticide that acts by targeting insect ryanodine receptors (RyRs), causing insect muscle dysfunction, paralysis and death. Flubendiamide disrupts molting, metamorphosis and reproductive processes, induces oxidative stress by increasing the levels of ROS/RNS, MDA and 8OHdG and decreasing the levels of SOD, CAT and GST, activates the CncC/Maf apoptosis pathway, impairs calcium homeostasis, promotes adipogenesis, increases triglyceride accumulation, and upregulates the expression of regulatory factors for adipocyte differentiation and adipogenesis .
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Cat. No.: HY-114636
CAS No.: 162326-49-0
Target:  

Insecticide

Research Areas:  

Others

RG-102240 is a ligand for insect ecdysone receptor (EcR), with IC50 of 85 and 13 nM, in wildtype G:CfE(DEF) and its A110P mutant. RG-102240 induces the reporter gene activity of wild-type CfEcR and A110P mutant .
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Cat. No.: HY-117386S
CAS No.: 2469014-53-5
Methoxyfenozide-d9 is the deuterium labeled Methoxyfenozide (HY-117386). Methoxyfenozide is an orally active insecticide belonging to the diacylhydrazine and non-steroidal ecdysone agonist classes, which can interfere with the growth and development of insects. Methoxyfenozide has ovicidal and insecticidal activities against phytophagous pests .
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Cat. No.: HY-N6979R
CAS No.: 5289-74-7
Synonyms: 20-Hydroxyecdysone (Standard)
Crustecdysone (Standard) is the analytical standard of Crustecdysone. This product is intended for research and analytical applications. Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
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Cat. No.: HY-W750355
CAS No.: 99399-65-2
Azadirachtin D is an insect growth regulator targeting ecdysone receptor (EcR) in insects. Azadirachtin D blocks the 20-hydroxyecdysone signaling pathway, leading to developmental arrest or death in insects. Azadirachtin D is promising for research of agricultural pests .
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Cat. No.: HY-B2054S
CAS No.: 2469006-89-9
Tebufenozide-d9 is the deuterium labeled Tebufenozide (HY-B2054). Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
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Cat. No.: HY-117386R
CAS No.: 161050-58-4
Research Areas:  

Infection

Methoxyfenozide (Standard) is the analytical standard of Methoxyfenozide (HY-117386). This product is intended for research and analytical applications. Methoxyfenozide is an orally active insecticide belonging to the diacylhydrazine and non-steroidal ecdysone agonist classes, which can interfere with the growth and development of insects. Methoxyfenozide has ovicidal and insecticidal activities against phytophagous pests.
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Cat. No.: HY-B2054R
CAS No.: 112410-23-8
Research Areas:  

Cancer

Tebufenozide (Standard) is the analytical standard of Tebufenozide (HY-B2054). This product is intended for research and analytical applications. Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
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Cat. No.: HY-N16479
CAS No.: 134788-16-2
Azadirachtin I is an insecticide targeting insect growth and development-related pathways (e.g., ecdysone signaling pathway, chitin synthesis pathway). Azadirachtin I inhibits chitin synthesis and disrupting intestinal function by interfering with the growth and development processes of insect larvae such as molting and pupation, increasing insect mortality and reducing adult fecundity. Azadirachtin I is promising for research of agricultural pests, such as Lepidoptera, Coleoptera .
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