93 Results for "

herpesvirus

" in MedChemExpress (MCE) Product Catalog:
Products (93)

93 Results for "herpesvirus" in MCE Product Catalog:

50
50 Publications Verification
Cat. No.: HY-15310
CAS No.: 70288-86-7
Purity:  98.28%
Synonyms: MK-933; CD-5024; K-237
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
loading...
    loading...
30
30 Cited Publications
Cat. No.: HY-13637
CAS No.: 82410-32-0
Purity:  99.89%
Synonyms: BW 759; 2'-Nor-2'-deoxyguanosine
Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
loading...
    loading...
30
30 Cited Publications
Cat. No.: HY-13637A
CAS No.: 107910-75-8
Purity:  99.92%
Synonyms: BW 759 sodium; 2'-Nor-2'-deoxyguanosine sodium
Ganciclovir (BW 759) sodium, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir sodium also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir sodium inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-B0307
CAS No.: 54-42-2
Synonyms: 5-Iodo-2′-deoxyuridine; 5-IUdR; IdUrd
Research Areas:  

Infection Cancer

Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-128744
CAS No.: 4408-78-0
Purity:  ≥98.0%
Phosphonoacetic acid is a potent antiviral agent. Phosphonoacetic acid inhibits a variety of herpesviruses, orthopoxviruses, and retroviruses. Phosphonoacetic acid strongly inhibits viral and cellular DNA polymerase, reverse transcriptase, and terminal deoxynucleotidyl transferase activities in a non-competitive or uncompetitive manner by binding to the pyrophosphate site of the enzyme. Phosphonoacetic acid is useful for research related to lymphoid leukemia, herpesvirus infection, and vaccinia virus skin lesions .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-N1401
CAS No.: 112246-15-8
20(R)-Ginsenoside Rh2 is an orally active protopanaxadiol-type saponin with multiple biological activities. 20(R)-Ginsenoside Rh2 exerts a significant inhibitory effect on non-small cell lung cancer and liver cancer by inducing cell cycle arrest and promoting apoptosis. 20(R)-Ginsenoside Rh2 exerts anti-γ-herpesvirus effects by inhibiting viral DNA replication. 20(R)-Ginsenoside Rh2 inhibits inflammatory mediators by reducing the levels of NO, PGE2, and ROS; it can delay skin photoaging by reducing ROS and inhibiting MMP-9/2 activity. 20(R)-Ginsenoside Rh2 accelerates the recovery after muscle injury by activating the Akt1/PKB signaling pathway. 20(R)-Ginsenoside Rh2 can inhibit osteoclast formation and exert an anti-osteoporosis effect .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P1258
CAS No.: 158442-41-2
Synonyms: Proteasome Inhibitor 1; Z-Ile-Glu(OtBu)-Ala-Leu-CHO
Target:  

Proteasome

Research Areas:  

Infection Cancer

PSI (Proteasome Inhibitor 1) is a potent proteasome inhibitor. PSI inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI has the potential for the research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P73837
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF14; Tumor Necrosis Factor Ligand Superfamily Member 14; TNF Superfamily Member 14; herpesvirus Entry Mediator Ligand; LIGHT; HVEML; HVEM-L; Tumor Necrosis Factor Superfamily Member 14; CD258; Herpes Virus Entry Mediator Ligand; LTg; Tumor Necrosis Fa
Species:  
Mouse
Source:  
Sf9 insect cells
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-17426
CAS No.: 104227-87-4
Synonyms: BRL 42810
Target:  

VZV HSV HBV

Research Areas:  

Infection

Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-17424
CAS No.: 39809-25-1
Synonyms: BRL 39123; VSA 671
Target:  

HSV

Research Areas:  

Infection

Penciclovir (VSA 671) is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 μg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir shows anti-herpesvirus activity with no-toxic. Penciclovir preventes mortality in mouse .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-116174
CAS No.: 124265-89-0
Purity:  99.47%
Synonyms: H2G
Target:  

HSV

Research Areas:  

Infection

Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P70494
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NECTIN1; OFC7; Prev. PVRL1; Poliovirus Receptor-Related 1 (herpesvirus Entry Mediator C); Prev. HVEC; herpesvirus Ig-Like Receptor; Prev. ED4; Ectodermal Dysplasia 4 (Margarita Island Type); Nectin-1; Herpes Simplex Virus Type 1 Sensitivity; PRR1; Herpesv
Species:  
Human
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P702603
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP7; HAUSP; Ubiquitin Specific Peptidase 7; Ubiquitin-Specific-Processing Protease 7; Ubiquitin Carboxyl-Terminal Hydrolase 7; Deubiquitinating Enzyme 7; Ubiquitin Thioesterase 7; Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated); herpesvirus-Asso
Species:  
Human
Source:  
E. coli
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P74478
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP7; HAUSP; Ubiquitin Specific Peptidase 7; Ubiquitin-Specific-Processing Protease 7; Ubiquitin Carboxyl-Terminal Hydrolase 7; Deubiquitinating Enzyme 7; Ubiquitin Thioesterase 7; Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated); herpesvirus-Asso
Species:  
Human
Source:  
Sf9 insect cells
loading...
    loading...
Cat. No.: HY-16721
CAS No.: 632325-71-4
Synonyms: Filociclovir; ZSM-I-62; MBX-400
Target:  

CMV

Research Areas:  

Infection

Cyclopropavir (Filociclovir) is an orally active and broad-spectrum anti-herpesvirus compound. Cyclopropavir inhibits UL97 kinase activity. Cyclopropavir has antiviral activity against HCMV, MCMV, and HAdV6 viruses .
loading...
    loading...
Cat. No.: HY-50735
CAS No.: 69123-90-6
Synonyms: NSC 382097; FIAC; FOAC
Target:  

HSV EBV DNA/RNA Synthesis

Research Areas:  

Infection

Fiacitabine (NSC 382097; FIAC; FOAC) is a potent and highly selective anti-herpesvirus agent. Fiacitabine acts as an inhibitor of HSV DNA polymerase, with a Ki of 0.26 μM for HSV-1 and 0.42 μM for HSV-2, respectively. Fiacitabine can be efficiently phosphorylated by thymidine kinase encoded by the virus itself to generate FIACTP, an active triphosphate metabolite. Fiacitabine is applicable to research related to herpesvirus infections .
loading...
    loading...
Cat. No.: HY-138130
CAS No.: 26578-09-6
Purity:  ≥98.0%
Research Areas:  

Infection Cancer

L-Guanosine is the L-configuration of Guanosine (HY-N0097). L-Guanosine is a purine nucleoside with anti-herpesvirus activity. L-Guanosine can be used to prepare supramolecular hydrogel .
loading...
    loading...
Cat. No.: HY-13637S
CAS No.: 1189966-73-1
Purity:  98.32%
Synonyms: BW 759-d5; 2'-Nor-2'-deoxyguanosine-d5
Ganciclovir-d5 is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) .
loading...
    loading...
Cat. No.: HY-13637R
CAS No.: 82410-32-0
Synonyms: BW 759 (Standard); 2'-Nor-2'-deoxyguanosine (Standard)
Ganciclovir (Standard) is the analytical standard of Ganciclovir. This product is intended for research and analytical applications. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
loading...
    loading...
Cat. No.: HY-P3795
CAS No.: 361443-81-4
Target:  

HSV

Research Areas:  

Infection Neurological Disease

G2-Peptide is a 3-O-sulfated heparan sulfate (3-OS HS) binder and antiviral agent. G2-Peptide blocks herpesvirus attachment, entry, cell-to-cell spread and syncytium formation, and reduces viral protein translocation. G2-Peptide exhibits antiviral activity against both HSV-1 and HSV-2. G2-Peptide inhibits neural activity and impairs synapse assembly. G2-Peptide can be used in the research of genital herpes, ocular herpes infection and keratitis .
loading...
    loading...