39809-25-1
39809-25-1
Chemical Structure
Penciclovir
Synonym(s): BRL 39123; VSA 671
- CAS No.: 39809-25-1
- Formula:C10H15N5O3
- Molecular Weight:253.26
IUPAC Name: 2-amino-9-(4-hydroxy-3-(hydroxymethyl)butyl)-1,9-dihydro-6H-purin-6-one
InChIKey: JNTOCHDNEULJHD-UHFFFAOYSA-N
SMILES: O=C1NC(N)=NC2=C1N=CN2CCC(CO)CO
Biological Activity: Penciclovir (VSA 671) is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 μg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir shows anti-herpesvirus activity with no-toxic. Penciclovir preventes mortality in mouse[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Penciclovir | 99.81% | Penciclovir (VSA 671) is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 μg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir shows anti-herpesvirus activity with no-toxic. Penciclovir preventes mortality in mouse. | ||||||||||||||||||||
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Penciclovir (Standard) | 99.44% | Penciclovir (Standard) is the analytical standard of Penciclovir. This product is intended for research and analytical applications. Penciclovir (VSA 671) is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 µg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir shows anti-herpesvirus activity with no-toxic. Penciclovir preventes mortality in mouse. | ||||||||||||||||||||
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Penciclovir-d4 | Penciclovir-d4 is the deuterium labeled Penciclovir. Penciclovir is reported to be potent against HSV types 1 and 2 with IC50 of 0.04-1.8 μg/mL and 0.06-4.4 μg/mL, respectively. | |||||||||||||||||||||
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References
- [1]. M.R. Boyd, et al. Penciclovir: a review of its spectrum of activity, selectivity, and cross-resistance pattern. Antiviral Chemistry and Chemotherapy, 1993, (1): 3-11.
- [2]. de la Fuente R, et al. The acyclic nucleoside analogue penciclovir is a potent inhibitor of equine herpesvirus type 1 (EHV-1) in tissue culture and in a murine model. Antiviral Res. 1992 May;18(1):77-89. [Content Brief]
