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Results for "

influenza A virus subtypes

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

4

Inhibitory Antibodies

3

Natural
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1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99750
    Navivumab

    CT-P23

    		 Influenza Virus Infection
    Navivumab (CT-P23) is a monoclonal antibody targeting the hemagglutinin (HA) of influenza A virus. Navivumab binds to the HA2 stem fusion domain and the low-variability HA2 region of influenza viruses. Navivumab neutralizes influenza A viruses of subtypes H1, H2, H5, and H9. Navivumab is applicable to research related to influenza and influenza A .
    Navivumab
  • HY-17015
    Peramivir trihydrate
    10+ Cited Publications

    RWJ 270201 trihydrate; BCX 1812 trihydrate

    		 Influenza Virus IKK JNK STAT p38 MAPK ERK Infection Inflammation/Immunology
    Peramivir trihydrate (RWJ-270201 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes .
    Peramivir trihydrate
  • HY-175469
    VNT-101

    		Influenza Virus Infection
    VNT-101 is an orally active influenza A (IAV) inhibitor. VNT-101 disrupts NP-NP PPI to block NP oligomerization and destabilize the viral ribonucleoprotein (RNP) complex, with potent antiviral activity across multiple influenza A subtypes. VNT-101 exhibits EC50 values of 4-5 nM in cellular cytopathic effect (CPE) assay, 4-8 nM in neuraminidase (NA) assay, and 21-45 nM in RNP assay. VNT-101 demonstrates robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus. VNT-101 can be used for the study of influenza A infection .
    VNT-101
  • HY-I0736
    Isonicotinic acid

    		MOFs Drug Metabolite Drug Intermediate Infection
    Isonicotinic acid is an Isoniazid (HY-B0329) metabolite. The Isonicotinic acid derivative Enisamium inhibits the replication of multiple subtypes of influenza A virus .
    Isonicotinic acid
  • HY-P991059
    VIS-410

    		Influenza Virus Infection
    VIS-410 is an antibody inhibitor targeting the stem region of hemagglutinin (HA). VIS-410 inhibits influenza virus replication by blocking HA-mediated membrane fusion. VIS-410 exhibits broad-spectrum neutralization against influenza A viruses with group 1 and group 2 hemagglutinins, including subtypes such as H1N1, H3N2, H5N1, and H7N9 (H5N1 IC50 = 1.5 μg/mL). VIS-410 is applicable to research related to influenza A virus infection .
    VIS-410
  • HY-B1404
    Nylidrin hydrochloride

    Buphenine hydrochloride

    		 iGluR Influenza Virus Infection Cardiovascular Disease Inflammation/Immunology
    Nylidrin hydrochloride (Buphenine hydrochloride) is an orally active β-adrenergic agonist. Nylidrin hydrochloride antagonizes NR1A/2B NMDA receptors (IC50 = 0.18 μM in Xenopus oocytes). Nylidrin hydrochloride reduces the levels of NP, HA, and M1. Nylidrin hydrochloride has antiviral activity against multiple H1N1 subtype influenza A viruses. Nylidrin hydrochloride improves hemorrhagic shock and anti-allergic effects .
    Nylidrin hydrochloride
  • HY-N12110
    SMU-CX1

    		Toll-like Receptor (TLR) SARS-CoV Infection
    SMU-CX1 is a specific TLR3 inhibitor (IC50: 0.11 μM) with IC50 ranging from 0.14-0.33 μM against multiple influenza A virus subtypes. SMU-CX1 inhibits the viral PB2 and NP proteins with an IC50 of 0.43 μM for SARS-CoV-2 activity. SMU-CX1 also inhibits inflammatory factors in host cells, including IFN-β, IP-10, and CCL-5 .
    SMU-CX1
  • HY-131179
    Influenza A virus-IN-1

    		Influenza Virus Infection
    Influenza A virus-IN-1 is a dihydropyrrolidones derivative and is a potent inhibitor against wide subtypes of influenza A virus (IAV) with IC50 values from 3.11 μM to 7.13 μM. Influenza A virus-IN-1 efficiently inhibits replication of IAV, up-regulates the expression of key antiviral cytokines IFN-β and antiviral protein MxA .
    Influenza A virus-IN-1
  • HY-17015R
    Peramivir trihydrate (Standard)

    RWJ 270201 trihydrate (Standard); BCX 1812 trihydrate (Standard)

    		 Reference Standards Influenza Virus Infection
    Peramivir (trihydrate) (Standard) is the analytical standard of Peramivir (trihydrate). This product is intended for research and analytical applications. Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes .
    Peramivir trihydrate (Standard)
  • HY-100858
    PP7

    		Influenza Virus Infection
    PP7 is a potent PB1-PB2 interaction inhibitor with an IC50 of 8.6 μM, and their inhibition against viral polymerase activity (IC50=9.5 μM). PP7 shows antiviral activities against influenza A virus (IAV), including A(H1N1)pdm09 (EC50=1.4 μM), A(H7N9) and A(H9N2) subtypes .
    PP7
  • HY-119213
    BMY-27709

    		Influenza Virus Infection
    BMY-27709 is an influenza virus growth inhibitor with an IC50 value of 3-8 μM against A/WSN/33 virus growth, and also exhibits inhibitory activity against some subtypes of influenza viruses. BMY-27709 acts early in the course of H1 and H2 virus infections, and exhibits antiviral activity through inhibition of hemagglutinin proteins. However, BMY-27709 has no effect on H3 subtype viruses and influenza B/Lee/40 viruses .
    BMY-27709
  • HY-155110
    Antiviral agent 34

    		DNA/RNA Synthesis Influenza Virus Infection
    Antiviral agent 34 is a potent and orally active antiviral agent against influenza A and B subtypes with an EC50 value of 0.8 nM for H1N1 proliferation. Antiviral agent 34 derivatives inhibited influenza virus proliferation by targeting influenza virus RNA-dependent RNA polymerase. Antiviral agent 34 can be used for influenza virus research .
    Antiviral agent 34
  • HY-I0736S
    Isonicotinic acid-d4

    		Drug Metabolite Isotope-Labeled Compounds Drug Intermediate Infection
    Isonicotinic acid-d4 is the deuterium labeled Isonicotinic acid (HY-I0736). Isonicotinic acid is an Isoniazid (HY-B0329) metabolite. The Isonicotinic acid derivative Enisamium inhibits the replication of multiple subtypes of influenza A virus .
    Isonicotinic acid-d4
  • HY-I0736R
    Isonicotinic acid (Standard)

    		Reference Standards Drug Metabolite Drug Intermediate Infection
    Isonicotinic acid (Standard) is the analytical standard of Isonicotinic acid (HY-I0736). This product is intended for research and analytical applications. Isonicotinic acid is an Isoniazid (HY-B0329) metabolite. The Isonicotinic acid derivative Enisamium inhibits the replication of multiple subtypes of influenza A virus .
    Isonicotinic acid (Standard)
  • HY-183929
    Antiviral agent 87

    		Influenza Virus Infection
    Antiviral agent 87 is a potent antiviral agent with low cytotoxicity in host cells. Antiviral agent 87 stabilizes prefusion HA conformation, blocks viral membrane fusion and host cell entry, and inhibits entry and replication of diverse influenza A virus subtypes. Antiviral agent 87 can be used for the research of influenza A virus infection .
    Antiviral agent 87
  • HY-B1404R
    Nylidrin hydrochloride (Standard)

    Buphenine hydrochloride (Standard)

    		 Reference Standards iGluR Influenza Virus Infection Cardiovascular Disease Inflammation/Immunology
    Nylidrin (hydrochloride) (Standard) is the analytical standard of Nylidrin hydrochloride (HY-B1404). This product is intended for research and analytical applications. Nylidrin hydrochloride (Buphenine hydrochloride) is an orally active β-adrenergic agonist. Nylidrin hydrochloride antagonizes NR1A/2B NMDA receptors (IC50 = 0.18 μM in Xenopus oocytes). Nylidrin hydrochloride reduces the levels of NP, HA, and M1. Nylidrin hydrochloride has antiviral activity against multiple H1N1 subtype influenza A viruses. Nylidrin hydrochloride improves hemorrhagic shock and anti-allergic effects .
    Nylidrin hydrochloride (Standard)
  • HY-P992083
    Anti-Influenza HA Antibody (CR9114)

    		Influenza Virus Infection
    Anti-Influenza HA Antibody (CR9114) is an antibody against influenza virus hemagglutinin. Anti-Influenza HA Antibody (CR9114) binds to the conserved hemagglutinin (HA) stalk region of influenza A and B viruses, and mediates cross-subtype neutralization. Anti-Influenza HA Antibody (CR9114) is applicable for influenza-related research .
    Anti-Influenza HA Antibody (CR9114)
  • HY-178455
    Influenza virus-IN-10

    		Influenza Virus Infection
    Influenza virus-IN-10 is a dual-target antiviral agents for influenza that targets both PAC (KD = 8.9 μM) and NP (KD = 52.5 μM) simultaneously. Influenza virus-IN-10 exhibits an EC50 values of 1.64 μM) against influenza A virus (H1N1, A/WSN/33) and broad-spectrum activity against other influenza strains, including influenza B virus and multiple subtypes of influenza A .
    Influenza virus-IN-10
  • HY-P992078
    Anti-Flu A (H3N2) HA/Hemagglutinin Antibody (C05)

    		Influenza Virus Infection
    Anti-Flu A (H3N2) HA/Hemagglutinin Antibody (C05) is a broad-spectrum neutralizing antibody that targets multiple influenza A HA subtypes. Anti-Flu A (H3N2) HA/Hemagglutinin Antibody (C05) is applicable to research related to influenza A virus infection .
    Anti-Flu A (H3N2) HA/Hemagglutinin Antibody (C05)

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