52 Results for "

lipoic acid

" in MedChemExpress (MCE) Product Catalog:
Products (52)

52 Results for "lipoic acid" in MCE Product Catalog:

11
11 Cited Publications
Cat. No.: HY-18733
CAS No.: 1200-22-2
Synonyms: (R)-(+)-α-lipoic acid; R-(+)-Thioctic acid
Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.
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14
14 Cited Publications
Cat. No.: HY-N0492
CAS No.: 1077-28-7
Synonyms: Thioctic acid; (±)-α-lipoic acid; DL-α-lipoic acid
α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .
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27
27 Publications Verification
Cat. No.: HY-15453
CAS No.: 95809-78-2
Purity:  99.59%
Synonyms: CPI-613
Research Areas:  

Cancer

Devimistat is a mitochondrial metabolism inhibitor. Devimistat is a lipoic acid antagonist that abrogates mitochondrial energy metabolism to induce apoptosis in various cancer cells .
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14
14 Cited Publications
Cat. No.: HY-N0492A
CAS No.: 2319-84-8
Synonyms: Thioctic acid sodium; (±)-α-lipoic acid sodium; DL-α-lipoic acid sodium
α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .
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10
10 Cited Publications
Cat. No.: HY-B1142
CAS No.: 940-69-2
Synonyms: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .
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3
3 Cited Publications
Cat. No.: HY-141336
CAS No.: 40846-94-4
Purity:  ≥98.0%
Synonyms: DL-α-lipoic acid-NHS
Target:  

PROTAC Linkers

Research Areas:  

Cancer

α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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1
1 Cited Publications
Cat. No.: HY-N0492S
CAS No.: 1189471-66-6
Synonyms: Thioctic acid-d5; (±)-α-lipoic acid-d5; DL-α-lipoic acid-d5
α-Lipoic Acid-d5 is the deuterium labeled α-Lipoic Acid. α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells .
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1
1 Cited Publications
Cat. No.: HY-18733R
CAS No.: 1200-22-2
Synonyms: (R)-(+)-α-lipoic acid(Standard); R-(+)-Thioctic acid (Standard)
Lipoic acid (Standard) is the analytical standard of Lipoic acid. This product is intended for research and analytical applications. Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.
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1
1 Cited Publications
Cat. No.: HY-P81072
Synonyms: HUSSY 01; LAS; LIP 1; Lip syn; LIP1; Lipoate synthase; lipoic acid synthetase; lipoic acid synthetase mitochondrial; Lipoyl synthase, mitochondrial; LS; MGC23245.

Host:  

Rabbit

Application:  

IHC-P, IHC-F, ICC/IF, ELISA

Reactivity:  

Mouse

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Cat. No.: HY-134633
CAS No.: 1808266-58-1
Synonyms: EV 06 chloride; UNR 844 chloride
Target:  

Drug Intermediate

Research Areas:  

Neurological Disease

Alpha-lipoic acid choline ester (EV 06) chloride is choline ester of alpha-lipoic acid. Alpha-lipoic acid choline ester chloride reduces the disulfide bond level of lens proteins. Alpha-lipoic acid choline ester chloride improves lens elasticity. Alpha-lipoic acid choline ester chloride is hydrolyzed by ocular esterases to release alpha-lipoic acid and choline. Alpha-lipoic acid choline ester chloride is used for the research of presbyopia .
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Cat. No.: HY-119152
CAS No.: 910627-26-8
Purity:  99.42%
Research Areas:  

Others

CMX-2043 is a novel analogue of α-Lipoic Acid (HY-N0492). CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model .
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Cat. No.: HY-151655
CAS No.: 118162-45-1
Purity:  99.35%
Target:  

ADC Linkers

Research Areas:  

Others

11-Azidoundecanoic acid is a click chemistry reagent containing an azide group. 11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. 11-Azidoundecanoic acid is substrate of lipoic acid ligase (LpIA) for labeling . 11-Azidoundecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-W014590
CAS No.: 1077-27-6
Synonyms: (S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid
(S)-Thioctic acid ((S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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Cat. No.: HY-N0492R
CAS No.: 1077-28-7
Synonyms: Thioctic acid (Standard); (±)-α-lipoic acid (Standard); DL-α-lipoic acid (Standard)
α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .
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Cat. No.: HY-146133
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

LA-Bac8c is a Lipoic acid modified antimicrobial peptide with enhanced antimicrobial properties. LA-Bac8c inhibits S. aureus, MRSA, S. epidermidis, E. coli, and P. aeruginosa with MICs of 1, 4, 8, 8, and 8 μg/mL .
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Cat. No.: HY-151802
CAS No.: 2043660-80-4
Target:  

TrxR

Research Areas:  

Cancer

CPUL1 is a TrxR inhibitor, which shows proliferation-inhibitory and anti-metastatic activity against A549 cells. CPUL1 influences EMT (epithelial-mesenchymal transition) via inducing ROS-mediated ERK/JNK signaling by inhibiting TrxR1 enzyme activity. CPUL1 in combination with α-Lipoic Acid (HY-N0492) or Dithiodipropionic acid (HY-W014395) is more effective .
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Cat. No.: HY-W014590R
CAS No.: 1077-27-6
Synonyms: (S)-lipoic acid (Standard); (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid (Standard)
(S)-Thioctic acid ((S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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Cat. No.: HY-147547
CAS No.: 2581825-37-6
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

SV5 is a potent anti-Alzheimer agent. SV5 can significantly protect SHSY-5Y cells against 1-42-induced death. SV5 shows moderate antioxidant and good neuroprotective activities. SV5 shows the high stability in human plasma and the best pharmacological profile .
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Cat. No.: HY-174912E
DBCO-PEG5000-LA is a PEG derivative consisting of DBCO, PEG units, and Lipoic Acid (HY-18733). DBCO-PEG5000-LA contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
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Cat. No.: HY-N0492AR
CAS No.: 2319-84-8
Synonyms: Thioctic acid sodium (Standard); (±)-α-lipoic acid sodium (Standard); DL-α-lipoic acid sodium (Standard)
α-Lipoic Acid (sodium) (Standard) is the analytical standard of α-Lipoic Acid (sodium). This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1.
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