181 Results for "

mUC

" in MedChemExpress (MCE) Product Catalog:
Products (181)

181 Results for "mUC" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N2098
CAS No.: 477-85-0
Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein .
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4
4 Cited Publications
Cat. No.: HY-N2609
CAS No.: 2196-14-7
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor (IC50=0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production . 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM .
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4
4 Cited Publications
Cat. No.: HY-P7696
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuCA125, His; CA125 ovarian cancer antigen; CA125; CA125mUC-16;
Species:  
Source:  
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4
4 Cited Publications
Cat. No.: HY-100958
CAS No.: 1952-15-4
Purity:  99.96%
Synonyms: 4-DAMP methiodide
4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion .
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2
2 Cited Publications
Cat. No.: HY-P1925A
CAS No.: 1222186-26-6
Research Areas:  

Cancer

GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .
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1
1 Cited Publications
Cat. No.: HY-B0393
CAS No.: 13189-98-5
Research Areas:  

Inflammation/Immunology

Fudosteine is a cysteine derivative and a mucoactive agent. Fudosteine inhibits MUC5AC mucin hypersecretion by reducing MUC5AC gene expression .
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1
1 Cited Publications
Cat. No.: HY-P99634
CAS No.: 1264737-26-9
Synonyms: PankoMab; DS-3939a antibody

Target:  

Mucin

Research Areas:  

Cancer

Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) .
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1
1 Cited Publications
Cat. No.: HY-NP159
House Dust Mite Extract, from D.farinae is a house dust mite allergen extract derived from Dermatophagoides farinae. House Dust Mite Extract, from D.farinae significantly increases the levels of cytokines (IL-4, IL-5, IL-6) in bronchoalveolar lavage fluid. House Dust Mite Extract, from D.farinae upregulates the overexpression of MUC5AC. House Dust Mite Extract, from D.farinae induces allergic asthma and pulmonary inflammation .
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Cat. No.: HY-P2508
CAS No.: 149205-73-2
Target:  

Mucin

Research Areas:  

Cancer

MUC1, mucin core is the region of the MUC1 mucin core. MUC1 is a type I transmembrane glycoprotein, and is overexpressed and aberrantly glycosylated in carcinoma cells. MUC1, mucin core protein binds to domain 1 of ICAM-1 .
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Cat. No.: HY-168973
CAS No.: 1285607-08-0
Synonyms: AER-01; mUC-031
Target:  

Mucin

Research Areas:  

Inflammation/Immunology

Fexlamose (AER-01) is a thiol-modified carbohydrate agent with mucolytic property. Fexlamose cleaves disulfides to cause mucolysis. Fexlamose can be used for researchs of chronic obstructive pulmonary disease (COPD) and muco-obstructive lung diseases (MOLD) .
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Cat. No.: HY-P0280
CAS No.: 244049-41-0
Target:  

Mucin

Research Areas:  

Inflammation/Immunology Cancer

MUC5AC motif peptide is a 16-amino acid fragment of mucin 5.
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Cat. No.: HY-RS19923
Research Areas:  

Others

Muc4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Muc4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P5512
CAS No.: 869012-66-8
Target:  

Peptides

Research Areas:  

Others

MUC5AC-3 is a biological active peptide. (glycopeptide transferase, ppGaNTase-T9 substrate)
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Cat. No.: HY-P5508
CAS No.: 869012-67-9
Target:  

Peptides

Research Areas:  

Others

MUC5AC-13 is a biological active peptide. (This glycopeptide is an N-acetyl galactosamine (GalNAc)-modified MUC5AC mucin peptide containing the single site of threonine 13 labeled with GalNAc (T*). Polypeptide N-acetylgalactosaminyltransferase (ppGaNTase) catalyzes the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to threonine. The MUC5AC gene is mainly expressed in gastric and tracheo-bronchial mucosae, and some tumors.)
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Cat. No.: HY-P5511
CAS No.: 869012-68-0
Target:  

Peptides

Research Areas:  

Others

MUC5AC-3/13 is a biological active peptide. (glycopeptide transferase, ppGaNTase-T9 substrate)
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Cat. No.: HY-RS08831
Research Areas:  

Others

MUC1 Human Pre-designed siRNA Set A contains three designed siRNAs for MUC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS08832
Research Areas:  

Others

MUC12 Human Pre-designed siRNA Set A contains three designed siRNAs for MUC12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS08833
Research Areas:  

Others

MUC13 Human Pre-designed siRNA Set A contains three designed siRNAs for MUC13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS08834
Research Areas:  

Others

MUC15 Human Pre-designed siRNA Set A contains three designed siRNAs for MUC15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS08835
Research Areas:  

Others

MUC16 Human Pre-designed siRNA Set A contains three designed siRNAs for MUC16 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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