Search Result
Results for "
motion
" in MedChemExpress (MCE) Product Catalog:
3
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-W010892
-
|
Hyoscine hydrobromide trihydrate
|
mAChR
5-HT Receptor
|
Neurological Disease
|
|
Scopolamine (Hyoscine) hydrobromide trihydrate is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrobromide trihydrate competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrobromide trihydrate can induce cognitive and memory deficits in animals. Scopolamine hydrobromide trihydrate can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
|
-
-
- HY-B0349
-
|
Meclozine dihydrochloride
|
Histamine Receptor
Apoptosis
|
Neurological Disease
Endocrinology
Cancer
|
|
Meclizine (Meclozine) dihydrochloride, an antihistamine, reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine dihydrochloride is a member of the piperazine class of H1 antagonists. Meclizine dihydrochloride is an effective anti-motion sickness agent. Meclizine dihydrochloride crosses the blood-brain barrier. Meclizine dihydrochloride can be used for the research of polyQ toxicity disorders, such as Huntington's disease. Meclizine dihydrochloride is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR .
|
-
-
- HY-B1215
-
|
|
Histamine Receptor
|
Neurological Disease
Endocrinology
|
Dimenhydrinate is an orally active H1-antihistamine consisting of Diphenhydramine (HY-B0303) and 8-Chlorotheophylline. Dimenhydrinate is used to prevent nausea, vomiting, dizziness, and vertigo associated with motion sickness .
|
-
-
- HY-B2065
-
|
(-)-Scopolamine hydrochloride; Hyoscine hydrochloride
|
mAChR
5-HT Receptor
|
Neurological Disease
|
|
Scopolamine (Hyoscine) hydrochloride is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrochloride competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrochloride can induce cognitive and memory deficits in animals. Scopolamine hydrochloride can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
|
-
-
- HY-D0947
-
|
|
DNA Stain
|
Others
|
|
Azure A chloride is a phenothiazine dye. Azure A chloride is an alternative DNA dye used for the separation of DNA and protein fragments in agarose gel electrophoresis and PAGE. Azure A chloride can be chemisorbed on the surface of mild steel according to the Langmuir adsorption isotherm to form a protective film. Azure A chloride binds to double-stranded DNA in a non-cooperative manner via weak intercalation, triggering molecular conformational disturbance, restricted rotational motion, and changes in optical activity .
|
-
-
- HY-W089353
-
|
|
MOFs
Fluorescent Dye
|
Others
|
|
8-Phenyl-BODIPY 505/515 is a molecular rotor based on the BODIPY scaffold, specifically used as a microviscosity probe. The working principle of 8-Phenyl-BODIPY 505/515 is based on the restriction of molecular motion by viscosity: in a high-viscosity environment, the rotational freedom of its chemical bonds is inhibited, which leads to a significant extension of fluorescence lifetime. This property makes 8-Phenyl-BODIPY 505/515 an effective tool for monitoring changes in the viscosity of intracellular microenvironments via fluorescence lifetime imaging (FLIM) technology .
|
-
-
- HY-P11430
-
|
|
Biochemical Assay Reagents
|
Infection
|
|
UBI (31-38) is a Ubiquicidin-derived octapeptide and anti-bacterial agent. UBI (31-38) selectively interacts with anionic phospholipid membranes and restricts lipid lateral motion. UBI (31-38) induces anionic vesicle aggregation via electrostatic repulsion screening, and undergoes conformational changes in membrane-mimicking environments. UBI (31-38) can be used for the research of infection imaging probes .
|
-
-
- HY-B0349A
-
|
Meclozine
|
Histamine Receptor
Apoptosis
|
Neurological Disease
Inflammation/Immunology
|
|
Meclizine (Meclozine), an antihistamine, reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine is a member of the piperazine class of H1 antagonists. Meclizine is an effective anti-motion sickness agent. Meclizine crosses the blood–brain barrier. Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR. Meclizine can be used for the research of polyQ toxicity disorders, such as Huntington's disease .
|
-
-
- HY-B1215R
-
|
|
Reference Standards
Histamine Receptor
|
Neurological Disease
Endocrinology
|
Dimenhydrinate (Standard) is the analytical standard of Dimenhydrinate. This product is intended for research and analytical applications. Dimenhydrinate is an orally active H1-antihistamine consisting of Diphenhydramine (HY-B0303) and 8-Chlorotheophylline. Dimenhydrinate is used to prevent nausea, vomiting, dizziness, and vertigo associated with motion sickness .
|
-
-
- HY-W010892S
-
|
Hyoscine-d3 hydrobromide
|
Isotope-Labeled Compounds
mAChR
5-HT Receptor
|
Neurological Disease
|
|
Scopolamine-d3 hydrobromide is the deuterium labeled Scopolamine hydrobromide (HY-B2065). Scopolamine (Hyoscine) hydrochloride is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrochloride competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrochloride can induce cognitive and memory deficits in animals. Scopolamine hydrochloride can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
|
-
-
- HY-W010892R
-
|
Hyoscine hydrobromide trihydrate (Standard)
|
mAChR
Reference Standards
5-HT Receptor
|
Neurological Disease
|
|
Scopolamine hydrobromide trihydrate (Standard) is the analytical standard of Scopolamine hydrobromide trihydrate (HY-W010892). This product is intended for research and analytical applications. Scopolamine (Hyoscine) hydrobromide is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrobromide competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrobromide can induce cognitive and memory deficits in animals. Scopolamine hydrobromide can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
|
-
-
- HY-B0349S
-
-
-
- HY-B1296S1
-
-
-
- HY-174686
-
|
|
mRNA
|
Cancer
|
|
Human FGFRL1 mRNA encodes the human fibroblast growth factor receptor like 1 (FGFRL1) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFRL1 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
|
-
-
- HY-174689
-
|
|
mRNA
|
Cancer
|
|
Human FGFR2 mRNA encodes the human fibroblast growth factor receptor 2 (FGFR2) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR2 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
|
-
-
- HY-174690
-
|
|
mRNA
|
Cancer
|
|
Human FGFR1 mRNA encodes the human fibroblast growth factor receptor 1 (FGFR1) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR1 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
|
-
-
- HY-160043
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
AL6 aptamer sodium is a short-chain nucleic acid aptamer chemically synthesized in vitro. AL6 aptamer sodium specifically targets Angiopoietin (Ang) for the specific detection of Ang. The AL6 aptamer binds to Ang, causing the rotational motion of the fluorophore on the AL6 aptamer to become slower. The concentration of Ang in the test solution can be quantified by detecting the anisotropy of AL6 aptamer/Ang .
|
-
-
- HY-B0349B
-
|
Meclozine dihydrochloride monohydrate
|
Histamine Receptor
Apoptosis
|
Neurological Disease
Inflammation/Immunology
|
|
Meclizine (Meclozine) dihydrochloride monohydrate, an antihistamine, reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine dihydrochloride is a member of the piperazine class of H1 antagonists. Meclizine dihydrochloride monohydrate is an effective anti-motion sickness agent. Meclizine dihydrochloride monohydrate crosses the blood-brain barrier. Meclizine dihydrochloride monohydrate is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR. Meclizine dihydrochloride monohydrate can be used for the research of polyQ toxicity disorders, such as Huntington's disease .
|
-
-
- HY-B0349R
-
|
Meclozine dihydrochloride (Standard)
|
Reference Standards
Histamine Receptor
Apoptosis
|
Neurological Disease
Endocrinology
Cancer
|
|
Meclizine (dihydrochloride) (Standard) is the analytical standard of Meclizine (dihydrochloride). This product is intended for research and analytical applications. Meclizine (Meclozine) dihydrochloride, an antihistamine, reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine dihydrochloride is a member of the piperazine class of H1 antagonists. Meclizine dihydrochloride is an effective anti-motion sickness agent. Meclizine dihydrochloride crosses the blood-brain barrier. Meclizine dihydrochloride can be used for the research of polyQ toxicity disorders, such as Huntington's disease. Meclizine dihydrochloride is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR .
|
-
-
- HY-174688
-
|
|
mRNA
|
Cancer
|
|
Human FGFR3 mRNA encodes the human fibroblast growth factor receptor 3 (FGFR3) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR3 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0947
-
|
|
Fluorescent Dye
|
|
Azure A chloride is a phenothiazine dye. Azure A chloride is an alternative DNA dye used for the separation of DNA and protein fragments in agarose gel electrophoresis and PAGE. Azure A chloride can be chemisorbed on the surface of mild steel according to the Langmuir adsorption isotherm to form a protective film. Azure A chloride binds to double-stranded DNA in a non-cooperative manner via weak intercalation, triggering molecular conformational disturbance, restricted rotational motion, and changes in optical activity .
|
-
- HY-W089353
-
|
|
Fluorescent Dye
|
|
8-Phenyl-BODIPY 505/515 is a molecular rotor based on the BODIPY scaffold, specifically used as a microviscosity probe. The working principle of 8-Phenyl-BODIPY 505/515 is based on the restriction of molecular motion by viscosity: in a high-viscosity environment, the rotational freedom of its chemical bonds is inhibited, which leads to a significant extension of fluorescence lifetime. This property makes 8-Phenyl-BODIPY 505/515 an effective tool for monitoring changes in the viscosity of intracellular microenvironments via fluorescence lifetime imaging (FLIM) technology .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P11430
-
|
|
Biochemical Assay Reagents
|
Infection
|
|
UBI (31-38) is a Ubiquicidin-derived octapeptide and anti-bacterial agent. UBI (31-38) selectively interacts with anionic phospholipid membranes and restricts lipid lateral motion. UBI (31-38) induces anionic vesicle aggregation via electrostatic repulsion screening, and undergoes conformational changes in membrane-mimicking environments. UBI (31-38) can be used for the research of infection imaging probes .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W010892
-
|
Hyoscine hydrobromide trihydrate
|
Alkaloids
Other Alkaloids
Datura metel L.
Solanaceae
Plants
Source Classification
|
mAChR
5-HT Receptor
|
|
Scopolamine (Hyoscine) hydrobromide trihydrate is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrobromide trihydrate competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrobromide trihydrate can induce cognitive and memory deficits in animals. Scopolamine hydrobromide trihydrate can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
|
-
-
- HY-B2065
-
|
(-)-Scopolamine hydrochloride; Hyoscine hydrochloride
|
Alkaloids
Other Alkaloids
Atropa belladonna Linn.
Solanaceae
Plants
Source Classification
|
mAChR
5-HT Receptor
|
|
Scopolamine (Hyoscine) hydrochloride is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrochloride competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrochloride can induce cognitive and memory deficits in animals. Scopolamine hydrochloride can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
|
-
-
- HY-W010892R
-
|
Hyoscine hydrobromide trihydrate (Standard)
|
Alkaloids
Structural Classification
Other Alkaloids
Datura metel L.
Solanaceae
Plants
Source Classification
|
mAChR
Reference Standards
5-HT Receptor
|
|
Scopolamine hydrobromide trihydrate (Standard) is the analytical standard of Scopolamine hydrobromide trihydrate (HY-W010892). This product is intended for research and analytical applications. Scopolamine (Hyoscine) hydrobromide is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrobromide competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrobromide can induce cognitive and memory deficits in animals. Scopolamine hydrobromide can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W010892S
-
|
|
|
Scopolamine-d3 hydrobromide is the deuterium labeled Scopolamine hydrobromide (HY-B2065). Scopolamine (Hyoscine) hydrochloride is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrochloride competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrochloride can induce cognitive and memory deficits in animals. Scopolamine hydrochloride can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
|
-
-
- HY-B0349S
-
|
|
|
Meclizine-d8 is a deuterium labeled Meclizine. Meclizine is a histamine H1 receptor antagonist and has the potential to treat nausea and motion sickness. Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR .
|
-
-
- HY-B1296S1
-
|
|
|
Promethazine-d4 is a deuterated-labeled promethazine (HY-B0781). Promethazine is an orally active H1 receptor and mAChR antagonist with antihistamine (H1), sedative, antiemetic, anticholinergic, and anti-motion sickness properties .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-174686
-
|
|
|
mRNA
|
|
Human FGFRL1 mRNA encodes the human fibroblast growth factor receptor like 1 (FGFRL1) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFRL1 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
|
-
- HY-174689
-
|
|
|
mRNA
|
|
Human FGFR2 mRNA encodes the human fibroblast growth factor receptor 2 (FGFR2) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR2 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
|
-
- HY-174690
-
|
|
|
mRNA
|
|
Human FGFR1 mRNA encodes the human fibroblast growth factor receptor 1 (FGFR1) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR1 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
|
-
- HY-160043
-
|
|
|
Aptamers
|
|
AL6 aptamer sodium is a short-chain nucleic acid aptamer chemically synthesized in vitro. AL6 aptamer sodium specifically targets Angiopoietin (Ang) for the specific detection of Ang. The AL6 aptamer binds to Ang, causing the rotational motion of the fluorophore on the AL6 aptamer to become slower. The concentration of Ang in the test solution can be quantified by detecting the anisotropy of AL6 aptamer/Ang .
|
-
- HY-174688
-
|
|
|
mRNA
|
|
Human FGFR3 mRNA encodes the human fibroblast growth factor receptor 3 (FGFR3) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR3 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
|
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