8 Results for "

nephrotic syndrome

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "nephrotic syndrome" in MCE Product Catalog:

1
Adrenocorticotropic hormone
Adrenocorticotropic hormone
0 Images
1 Cited Publications
Cat. No.: HY-106373
CAS No.: 9002-60-2
Purity:  99.17%
Synonyms: ACTH; Adrenocorticotrophic hormone
Target:  

Androgen Receptor Reactive Oxygen Species (ROS) Mitochondrial Metabolism Interleukin Related TNF Receptor

Research Areas:  

Metabolic Disease Inflammation/Immunology

Adrenocorticotropic hormone (ACTH; Adrenocorticotrophic hormone) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone stimulates cortisol secretion from the adrenal cortex via the hypothalamic-pituitary-adrenal (HPA) axis. Adrenocorticotropic hormone regulates cortisol and androgen production. Adrenocorticotropic hormone can promote the development of spermatogenesis. Adrenocorticotropic hormone can relieve acute inflammation in gout models by inhibiting the polarization of macrophages to M1 type, inhibiting ROS and proinflammatory factor production and protecting mitochondrial function. Adrenocorticotropic hormone can be used for the researches of inflammation, endocrinology, metabolic disease, such as gout and nephrotic syndrome .
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1
Adrenocorticotropic hormone TFA
Adrenocorticotropic hormone TFA
0 Images
1 Cited Publications
Cat. No.: HY-106373A
Purity:  99.85%
Synonyms: ACTH TFA; Adrenocorticotrophic hormone TFA
Target:  

Androgen Receptor Reactive Oxygen Species (ROS) Mitochondrial Metabolism Interleukin Related TNF Receptor

Research Areas:  

Metabolic Disease Inflammation/Immunology

Adrenocorticotropic hormone (ACTH; Adrenocorticotrophic hormone) TFA is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone TFA stimulates cortisol secretion from the adrenal cortex via the hypothalamic-pituitary-adrenal (HPA) axis. Adrenocorticotropic hormone TFA regulates cortisol and androgen production. Adrenocorticotropic hormone TFA can promote the development of spermatogenesis. Adrenocorticotropic hormone TFA can relieve acute inflammation in gout models by inhibiting the polarization of macrophages to M1 type, inhibiting ROS and proinflammatory factor production and protecting mitochondrial function. Adrenocorticotropic hormone TFA can be used for the researches of inflammation, endocrinology, metabolic disease, such as gout and nephrotic syndrome .
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Withaphysalin A
Withaphysalin A
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Cat. No.: HY-N11011
CAS No.: 57423-72-0
Category:  

Physalis minima Linn. Plants Solanaceae Extract Steroids

Target:  

NF-κB STAT PERK JNK p38 MAPK PGE synthase Interleukin Related TNF Receptor COX

Withaphysalin A is a withanolide compound with anti-inflammatory and antioxidant activities. Withaphysalin A inhibits LPS (HY-D1056)-induced nuclear translocation of NF-κB p65, as well as phosphorylation of STAT3, ERK, JNK and p38 MAPK. Withaphysalin A upregulates the expression of HO-1. Withaphysalin A inhibits LPS-induced production of NO, PGE2, IL-1β, IL-6 and TNF-α. Withaphysalin A downregulates LPS-induced expression of iNOS and COX-2. Withaphysalin A interacts with B-cell activating factor protein (BAFF) to exert inhibitory effects. Withaphysalin A exhibits ELOVL6 inhibitory activity. Withaphysalin A can be used in the research of inflammatory diseases, nephrotic syndrome and chronic myeloid leukemia .
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Sodium phosphate dibasic, meets analytical specification of Ph. Eur. BP USP FCC E339
Sodium phosphate dibasic, meets analytical specification of Ph. Eur. BP USP FCC E339
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Cat. No.: HY-Y0308D
CAS No.: 7558-79-4
Synonyms: Disodium hydrogen phosphate, meets analytical specification of Ph. Eur. BP USP FCC E339
Sodium phosphate dibasic (Disodium hydrogen phosphate), meets analytical specification of Ph. Eur. BP USP FCC E339 is an inorganic dibasic phosphate that functions as an electrolyte supplement, a buffer carrier for injectable drugs, while also exhibiting nephrotoxicity. Sodium phosphate dibasic, meets analytical specification of Ph. Eur. BP USP FCC E339 induces extensive nephrotic syndrome-like changes, including systemic symptoms such as persistent proteinuria, lipemia, hypercholesterolemia, and anemia, and causes severe renal pathological alterations such as renal enlargement, glomerular calcification, podocyte injury, and tubulointerstitial lesions. Sodium phosphate dibasic, meets analytical specification of Ph. Eur. BP USP FCC E339 has the ability to induce phosphate-induced nephropathy and glomerular calcification, and can be widely used in studies on nephrotic syndrome and related renal pathological mechanisms .
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Coenzyme Q6
Coenzyme Q6
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Cat. No.: HY-N9610
CAS No.: 1065-31-2
Synonyms: Ubiquinone 30
Category:  

Quinones Microorganisms Benzene Quinones

Target:  

Endogenous Metabolite

Coenzyme Q6 (Ubiquinone 30) is a redox-active benzoquinone lipid and mitochondrial electron carrier. Coenzyme Q6 can be used in research on MASLD, mitochondrial diseases, pneumococcal diseases, and steroid-resistant nephrotic syndrome with FSGS .
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Fenfangjine G
Fenfangjine G
0 Images
Cat. No.: HY-N8661
CAS No.: 205533-81-9
Category:  

Stephania tetrandra S. Moore Alkaloids Other Alkaloids Menispermaceae Extract Plants

Target:  

Others

Fenfangjine G is an active component in Fangji Huangqi Tang (FHT). Fenfangjine G can be used for the research of nephrotic syndrome .
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E822-1968
E822-1968
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Cat. No.: HY-183637
CAS No.: 1037259-63-4
Target:  

Urea Transporter

Research Areas:  

Cardiovascular Disease Metabolic Disease Endocrinology

E822-1968 is an UT-A2 inhibitor with a human IC50 of 0.44 μM. E822-1968 blocks urea transport mediated by UT-A2. E822-1968 can be used for the study of hyponatremia and edema associated with congestive heart failure, nephrotic syndrome, and cirrhosis .
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M353-0039
M353-0039
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Cat. No.: HY-183636
CAS No.: 1185074-29-6
Target:  

Urea Transporter

Research Areas:  

Cardiovascular Disease Metabolic Disease Endocrinology

M353-0039 is a selective UT-A2 inhibitor with a human IC50 of 0.35 μM. M353-0039 blocks urea transport mediated by UT-A2. M353-0039 can be used for the study of hyponatremia and edema associated with congestive heart failure, nephrotic syndrome, and cirrhosis .
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