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Results for "

propionic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (12) Amino Acid Derivatives (5) Apoptosis (1) Autophagy (1) Bacterial (2) Biochemical Assay Reagents (10) CDK (1) COX (2) Drug Intermediate (8) Drug Metabolite (3) Drug-Linker Conjugates for ADC (1) E3 Ligase Ligand-Linker Conjugates (2) Endogenous Metabolite (28) Environmental Pollutants (4) Fluorescent Dye (1) Fungal (3) Herbicide (2) iGluR (3) Influenza Virus (3) Isotope-Labeled Compounds (5) Ligands for Target Protein for PROTAC (1) LXR (1) Oxidative Phosphorylation (1) PANK (2) Parasite (2) PROTAC Linkers (10) Reactive Oxygen Species (ROS) (2) Reference Standards (13) TNF Receptor (1) Vasopressin Receptor (1)
By Research Areas:	Cancer (26) Cardiovascular Disease (5) Infection (7) Inflammation/Immunology (7) Metabolic Disease (22) Neurological Disease (5)
Click Chemistry:	ADC Synthesis (4) DBCO (2) Azide (2)
Oligonucleotides:	Phospholipids (1)

101

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W015229

3-Indolepropionic acid Maximum Cited Publications 10 Publications Verification Indole-3-propionic acid; 3-IPA	Endogenous Metabolite Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease
3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.

HY-W045271

*Imidazole-5-propionic* acid** 1 Publications Verification Imidazolepropionic acid	Endogenous Metabolite Amino Acid Derivatives	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Imidazole-5-propionic acid (Imidazolepropionic acid) is a urinary metabolite of L-histidine (HY-N0832). Imidazole-5-propionic acid can be used in the research of intestinal diseases and cardiovascular diseases .

HY-W015346

Desaminotyrosine 2 Publications Verification 3-(4-Hydroxyphenyl)propionic acid	Influenza Virus Endogenous Metabolite	Infection
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.

HY-Y1088

Hydrocinnamic acid 3-Phenylpropionic acid; 3-Phenylpropanoic acid; 3-Phenyl-n-propionic acid	Environmental Pollutants Endogenous Metabolite	Others
Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.

HY-W005255

*3-(3-Hydroxyphenyl)propionic* acid**	Endogenous Metabolite	Cardiovascular Disease
3-(3-Hydroxyphenyl)propionic acid (3HPPA) is an endothelium-dependent nitric oxide (NO) release promoter and endothelial nitric oxide synthase (eNOS) activator. 3-(3-Hydroxyphenyl)propionic acid activates eNOS to mediate vascular smooth muscle relaxation and enhances endothelial cell NO synthesis, inducing vasodilation and reducing peripheral vascular resistance. 3-(3-Hydroxyphenyl)propionic acid can dose-dependently reduce systolic and diastolic blood pressure in spontaneously hypertensive rats (SHR) without affecting cardiac contractility or heart rate. 3-(3-Hydroxyphenyl)propionic acid has antihypertensive and vascular protective effects and can be used in the prevention and treatment of cardiovascular diseases .

HY-113371

2-Methylcitric acid Methylcitric acid	Endogenous Metabolite	Metabolic Disease
2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-134424

Propionyl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms .

HY-140118

*Fmoc-NH-ethyl-SS-propionic* acid** 1 Publications Verification	ADC Linker	Cancer
Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-113285

Ureidopropionic acid 3-Ureidopropionic acid	Oxidative Phosphorylation	Metabolic Disease
Ureidopropionic acid is a mitochondrial respiratory chain complex V inhibitor that selectively inhibits the activity of mitochondrial respiratory chain complex V, with no effect on respiratory chain complexes I-IV or mitochondrial fatty acid β-oxidation. Ureidopropionic acid induces the production of reactive oxygen species, delayed elevation of intracellular calcium concentration, secondary energy-dependent excitotoxicity and neurodegeneration in neurons. Ureidopropionic acid promotes neuropathological changes by impairing mitochondrial energy metabolism, oxidative stress and excitotoxicity pathways. Ureidopropionic acid can be used in studies related to 3-ureidopropionase deficiency and severe propionic aciduria .

HY-101401

*3-(Methylthio)propionic* acid** 3-Methylsulfanylpropionic acid	Fungal Endogenous Metabolite	Cancer
3-(Methylthio)propionic acid is an intermediate in the methionine metabolism.

HY-130426

*Maleimido-tri(ethylene glycol)-propionic* acid** Mal-PEG3-acid	ADC Linker PROTAC Linkers	Cancer
Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation . Maleimido-tri(ethylene glycol)-propionic acid also can be used as a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-U00190

Deprodone propionate RD20000	Bacterial	Inflammation/Immunology
Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position.

HY-113158

4-Hydroxyhippuric acid	Drug Metabolite	Metabolic Disease
4-Hydroxyhippuric acid is a metabolite of polyphenols. 4-Hydroxyhippuric acid is generated via medium-chain acyl-CoA dehydrogenase (MCAD)-dependent β-oxidation of microbially-produced 3-(4-hydroxyphenyl)propionic acid, followed by host glycine conjugation. 4-Hydroxyhippuric acid can be simultaneously detected in urine as a biomarker of dietary polyphenol intake .

HY-W016482

*3-(3-Methoxyphenyl)propionic* acid**	Endogenous Metabolite	Metabolic Disease
3-(3-Methoxyphenyl) propionic acid is an organic acid and endogenous metabolite. 3-(3-Methoxyphenyl) propionic acid is excreted in urine .

HY-136166

*Thalidomide-NH-PEG3-propionic* acid**	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology .

HY-W013976

*3-(Acetylthio)propionic* acid N-succinimidyl ester**	Biochemical Assay Reagents	Others
3-(Acetylthio)propionic acid N-succinimidyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-103228

GYKI 53655 hydrochloride LY300168 hydrochloride	iGluR	Neurological Disease
GYKI 53655 (LY300168) hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) antagonist.

HY-B2013

Fenoxaprop-P-ethyl	Environmental Pollutants Herbicide	Others
Fenoxaprop-P-ethyl is a phenoxy propionic acid herbicide with a heterocyclic epoxide structure.

HY-W105506

Dimethylpropiothetin hydrochloride s,s-Dimethyl-β-propionic acid thetine	Drug Intermediate	Others
Dimethylpropiothetin hydrochloride is a dimethylsulfide precursor. Dimethylpropiothetin hydrochloride can be isolated from the marine coccolithophore Hymenomonas carterae. Dimethylpropiothetin hydrochloride participates in the maintenance of cellular osmotic pressure .

HY-159509

Claziprotamidum Claziprotamide; BBP-671	PANK	Neurological Disease Metabolic Disease
Claziprotamidum (Claziprotamide; BBP-671) is a panthothenate kinase (PANK) activator with oral activity and blood-brain barrier permeability. Claziprotamidum binds to and activates all PANK isoforms, with the highest affinity for PANK3 (K_D = 97 pM; IC₅₀ = 1.39 nM). Claziprotamidum increases the intracellular biosynthesis of Coenzyme A (HY-128851) and restores mitochondrial function. Claziprotamidum can be used in the research of pantothenate kinase-associated neurodegeneration and propionic acidemia .

HY-140096

*Aminoethyl-SS-propionic* acid**	ADC Linker	Cancer
Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W003499

*(S)-3-Benzyloxycarbonylamino-2-(Boc-amino)propionic* acid**	Amino Acid Derivatives	Others
(S)-3-Benzyloxycarbonylamino-2-(Boc-amino)propionic acid is an alanine derivative .

HY-W067425

*2-(4-Hydroxyphenyl)propionic* acid**	Endogenous Metabolite	Metabolic Disease
2-(4-Hydroxyphenyl)propionic acid (Compound 1) is an aromatic carboxylic acid, which can be converted into its R and S glucosyl esters and glucosides by root culture of P. ginseng (Pg-1) .

HY-15072

Zonampanel YM 872	iGluR	Metabolic Disease
Zonampanel (YM 872) is a selective antagonist of the glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor.

HY-W015229R

3-Indolepropionic acid (Standard) Indole-3-propionic acid (Standard); 3-IPA (Standard)	Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease
3-Indolepropionic acid (Standard) is the analytical standard of 3-Indolepropionic acid. This product is intended for research and analytical applications. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. In Vitro: 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease . 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds . It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function .

HY-130560

*Biotin-PEG3-propionic* hydrazide**	PROTAC Linkers	Cancer
Biotin-PEG3-propionic hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

HY-140120

*Mal-NH-ethyl-SS-propionic* acid**	ADC Linker	Cancer
Mal-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-113371A

2-Methylcitric acid trisodium Methylcitric acid trisodium	Endogenous Metabolite	Metabolic Disease
2-Methylcitric acid trisodium (Methylcitric acid trisodium) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid trisodium accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid trisodium markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-164909

PZ-3022	PANK	Inflammation/Immunology
PZ-3022 is an orally active and allosteric PanK activator that counteracts C3-CoA inhibition. PZ-3022 increases hepatic CoASH and C2-CoA and decreases C3-CoA in the propionic acidemia mouse model. PZ-3022 can be used for research of mitochondrial defect in propionic acidemia .

HY-34519

*(S)-2-Amino-3-(4-hydroxyphenyl)propionic* acid tert-butyl ester** L-Tyrosine tert-butyl ester; tert-Butyl (S)-2-amino-3-(4-hydroxyphenyl)propanoate; tert-Butyl L-tyrosinate	Amino Acid Derivatives	Others
(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid tert-butyl ester is a tyrosine derivative .

HY-B1580

Calcium propionate propionic acid calcium	Environmental Pollutants Biochemical Assay Reagents	Metabolic Disease
Calcium propionate is an orally active auxiliary agent for preventing milk fever and improving the health of dairy cows. Calcium propionate can be used for research on dairy cow milk fever and subclinical hypocalcemia .

HY-113406

(±)-Hexanoylcarnitine DL-Hexanoylcarnitine	Others	Inflammation/Immunology
(±)-Hexanoylcarnitine exists in human urine and plasma. (±)-Hexanoylcarnitine can be used as a plasma detection indicator in patients with methylmalonic aciduria, propionic acidemia, and medium-chain acyl-CoA dehydrogenase deficiency .

HY-W121901

Naproxen glucuronide (S)-Naproxen-β-D-glucuronide	COX	Inflammation/Immunology
Naproxen glucuronide ((S)-Naproxen-β-D-glucuronide) is a non-selective COX inhibitor. Naproxen glucuronide, a metabolite of naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain, fever, swelling, and stiffness .

HY-113371S

2-Methylcitric acid-d3 Methylcitric acid-d₃	Endogenous Metabolite	Metabolic Disease
2-Methylcitric acid-d₃ is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-Y1088S2

Hydrocinnamic acid-d9 3-Phenylpropionic acid-d₉; 3-Phenylpropanoic acid-d₉; 3-Phenyl-n-propionic acid-d₉	Endogenous Metabolite	Others
Hydrocinnamic acid-d₉ is the deuterium labeled Hydrocinnamic acid . Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activitie s.

HY-W018722

*3-(4-Aminophenyl)propionic* acid**	PROTAC Linkers	Cancer
3-(4-Aminophenyl)propionic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-78701

*3-(4-Bromobenzoyl)propionic* acid**	PROTAC Linkers	Cancer
3-(4-Bromobenzoyl)propionic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-140116

*Boc-NH-ethyl-SS-propionic* acid**	ADC Linker	Cancer
Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-N10914

*2-(2'-Hydroxy-4'-methylphenyl)propionic* acid**	Others	Others
2-(2'-Hydroxy-4'-methylphenyl)propionic acid is an active compound .

HY-140102

*Azidoethyl-SS-propionic* NHS ester**	ADC Linker	Cancer
Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-41638

*2-Acetylamino-3-(2-quinolon-4-yl)propionic* acid**	Drug Intermediate	Others
2-Acetylamino-3-(2-quinolon-4-yl)propionic acid is a drug intermediate for synthesis of various active compounds.

HY-133651

2,2-Dibromopropanoic acid	Fungal	Infection
2,2-Dibromopropanoic acid is a dibromo product based on propionic acid. Propionic acid is a short chain fatty acid and acts as chemical intermediate. Propionic acid is also a mold inhibitor and widely used in food preservative .

HY-126892

Bis-PEG7-acid	PROTAC Linkers ADC Linker	Cancer
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W105506S

Dimethylpropiothetin hydrochloride-d6 s,s-Dimethyl-β-propionic acid thetine-d₆	Isotope-Labeled Compounds	Others
(2-Carboxyethyl)dimethylsulfonium-d₆ chloride is the deuterium labeled (2-Carboxyethyl)dimethylsulfonium chloride .

HY-Y1088S3

Hydrocinnamic acid-d5 3-Phenylpropionic acid-d₅; 3-Phenylpropanoic acid-d₅; 3-Phenyl-n-propionic acid-d₅	Endogenous Metabolite	Others
Hydrocinnamic acid-d₅ is the deuterium labeled Hydrocinnamic acid . Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities .

HY-130981

*FN-1501-propionic* acid**	CDK Ligands for Target Protein for PROTAC	Cancer
FN-1501-propionic acid is a CDK2/9 ligand for PROTAC. FN-1501-propionic acid and a CRBN ligand have been used to design PROTAC CDK2/9 degrader (HY-130709) .

HY-N2926

*β-Carboline-1-propionic* acid**	Parasite	Infection
β-Carboline-1-propionic acid is a alkaloid which can be extracted from Ailanthus altissima. β-Carboline-1-propionic acid can be used as an antileishmanial agent .

HY-N7173

*7-Methoxy-β-carboline-1-propionic* acid**	Parasite	Infection
7-Methoxy-β-carboline-1-propionic acid (compound 46) is a cytotoxic and antimalarial compound. 7-Methoxy-β-carboline-1-propionic acid can be extracted from the roots of Eurycoma longifolia .

HY-W045271R

*Imidazole-5-propionic* acid (Standard)** Imidazolepropionic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Imidazole-5-propionic acid is a histidine metabolite .

HY-136141

*DBCO-PEG3-propionic* EVCit-PAB**	ADC Linker	Cancer
DBCO-PEG3-propionic EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-propionic EVCit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No.	Product Name	Type

HY-134424

Propionyl coenzyme A lithium	Biochemical Assay Reagents
Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms .

HY-B1580

Calcium propionate propionic acid calcium	Biochemical Assay Reagents
Calcium propionate is an orally active auxiliary agent for preventing milk fever and improving the health of dairy cows. Calcium propionate can be used for research on dairy cow milk fever and subclinical hypocalcemia .

HY-W143044

*(R)-3-Amino-3-(2-fluoro-phenyl)-propionic* acid**	Biochemical Assay Reagents
(R)-3-Amino-3-(2-fluoro-phenyl)-propionic acid is a non-proteinogenic amino acid that plays a role in the biosynthesis of various important molecules in organisms .

HY-174937

DNP-PEG3-acid DNP-PEG3-COOH	Biochemical Assay Reagents
DNP-PEG3-acid (DNP-PEG3-COOH) is a compound composed of 2,4-dinitroaniline (DNP), three PEG units, and propionic acid, which can be used for drug delivery.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015229

3-Indolepropionic acid Maximum Cited Publications 10 Publications Verification Indole-3-propionic acid; 3-IPA	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite Reactive Oxygen Species (ROS)
3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.

HY-W045271

*Imidazole-5-propionic* acid** 1 Publications Verification Imidazolepropionic acid	Structural Classification Alkaloids Classification of Application Fields Metabolic Disease Imidazole Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Amino Acid Derivatives
Imidazole-5-propionic acid (Imidazolepropionic acid) is a urinary metabolite of L-histidine (HY-N0832). Imidazole-5-propionic acid can be used in the research of intestinal diseases and cardiovascular diseases .

HY-W015346

Desaminotyrosine 2 Publications Verification 3-(4-Hydroxyphenyl)propionic acid	Infection Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields Source Classification	Influenza Virus Endogenous Metabolite
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.

HY-Y1088

Hydrocinnamic acid 3-Phenylpropionic acid; 3-Phenylpropanoic acid; 3-Phenyl-n-propionic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer Source Classification	Environmental Pollutants Endogenous Metabolite
Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.

HY-W005255

*3-(3-Hydroxyphenyl)propionic* acid**	Cardiovascular Disease Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
3-(3-Hydroxyphenyl)propionic acid (3HPPA) is an endothelium-dependent nitric oxide (NO) release promoter and endothelial nitric oxide synthase (eNOS) activator. 3-(3-Hydroxyphenyl)propionic acid activates eNOS to mediate vascular smooth muscle relaxation and enhances endothelial cell NO synthesis, inducing vasodilation and reducing peripheral vascular resistance. 3-(3-Hydroxyphenyl)propionic acid can dose-dependently reduce systolic and diastolic blood pressure in spontaneously hypertensive rats (SHR) without affecting cardiac contractility or heart rate. 3-(3-Hydroxyphenyl)propionic acid has antihypertensive and vascular protective effects and can be used in the prevention and treatment of cardiovascular diseases .

HY-113371

2-Methylcitric acid Methylcitric acid	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-113285

Ureidopropionic acid 3-Ureidopropionic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields	Oxidative Phosphorylation
Ureidopropionic acid is a mitochondrial respiratory chain complex V inhibitor that selectively inhibits the activity of mitochondrial respiratory chain complex V, with no effect on respiratory chain complexes I-IV or mitochondrial fatty acid β-oxidation. Ureidopropionic acid induces the production of reactive oxygen species, delayed elevation of intracellular calcium concentration, secondary energy-dependent excitotoxicity and neurodegeneration in neurons. Ureidopropionic acid promotes neuropathological changes by impairing mitochondrial energy metabolism, oxidative stress and excitotoxicity pathways. Ureidopropionic acid can be used in studies related to 3-ureidopropionase deficiency and severe propionic aciduria .

HY-101401

*3-(Methylthio)propionic* acid** 3-Methylsulfanylpropionic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Fungal Endogenous Metabolite
3-(Methylthio)propionic acid is an intermediate in the methionine metabolism.

HY-113158

4-Hydroxyhippuric acid	Immune System Disorder Disease markers Endogenous metabolite	Drug Metabolite
4-Hydroxyhippuric acid is a metabolite of polyphenols. 4-Hydroxyhippuric acid is generated via medium-chain acyl-CoA dehydrogenase (MCAD)-dependent β-oxidation of microbially-produced 3-(4-hydroxyphenyl)propionic acid, followed by host glycine conjugation. 4-Hydroxyhippuric acid can be simultaneously detected in urine as a biomarker of dietary polyphenol intake .

HY-W016482

*3-(3-Methoxyphenyl)propionic* acid**	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
3-(3-Methoxyphenyl) propionic acid is an organic acid and endogenous metabolite. 3-(3-Methoxyphenyl) propionic acid is excreted in urine .

HY-W105506

Dimethylpropiothetin hydrochloride s,s-Dimethyl-β-propionic acid thetine	Structural Classification Natural Products Gramineae Marine natural products Sporobolus anglicus (C.E.Hubb.) P.M.Peterson & Saarela Plants Source Classification	Drug Intermediate
Dimethylpropiothetin hydrochloride is a dimethylsulfide precursor. Dimethylpropiothetin hydrochloride can be isolated from the marine coccolithophore Hymenomonas carterae. Dimethylpropiothetin hydrochloride participates in the maintenance of cellular osmotic pressure .

HY-W015229R

3-Indolepropionic acid (Standard) Indole-3-propionic acid (Standard); 3-IPA (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS)
3-Indolepropionic acid (Standard) is the analytical standard of 3-Indolepropionic acid. This product is intended for research and analytical applications. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. In Vitro: 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease . 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds . It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function .

HY-113371A

2-Methylcitric acid trisodium Methylcitric acid trisodium	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
2-Methylcitric acid trisodium (Methylcitric acid trisodium) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid trisodium accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid trisodium markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-113406

(±)-Hexanoylcarnitine DL-Hexanoylcarnitine	Natural Products Animals Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Others
(±)-Hexanoylcarnitine exists in human urine and plasma. (±)-Hexanoylcarnitine can be used as a plasma detection indicator in patients with methylmalonic aciduria, propionic acidemia, and medium-chain acyl-CoA dehydrogenase deficiency .

HY-N10914

*2-(2'-Hydroxy-4'-methylphenyl)propionic* acid**	Labiatae Phenols Erythrina poeppigiana Plants Source Classification	Others
2-(2'-Hydroxy-4'-methylphenyl)propionic acid is an active compound .

HY-N2926

*β-Carboline-1-propionic* acid**	Alkaloids Simaroubaceae Ailanthus altissima (Mill.) Swingle Pyrrole Alkaloids Plants Source Classification	Parasite
β-Carboline-1-propionic acid is a alkaloid which can be extracted from Ailanthus altissima. β-Carboline-1-propionic acid can be used as an antileishmanial agent .

HY-N7173

*7-Methoxy-β-carboline-1-propionic* acid**	Alkaloids other families Ketones, Aldehydes, Acids Eurycoma longifolia Jack Plants	Parasite
7-Methoxy-β-carboline-1-propionic acid (compound 46) is a cytotoxic and antimalarial compound. 7-Methoxy-β-carboline-1-propionic acid can be extracted from the roots of Eurycoma longifolia .

HY-W045271R

*Imidazole-5-propionic* acid (Standard)** Imidazolepropionic acid (Standard)	Structural Classification Alkaloids Imidazole Alkaloids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Imidazole-5-propionic acid is a histidine metabolite .

HY-Y1088R

Hydrocinnamic acid (Standard) 3-Phenylpropionic acid (Standard); 3-Phenylpropanoic acid (Standard); 3-Phenyl-n-propionic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Cancer Source Classification	Reference Standards Endogenous Metabolite
Hydrocinnamic acid (Standard) is the analytical standard of Hydrocinnamic acid. This product is intended for research and analytical applications. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.

HY-101401R

*3-(Methylthio)propionic* acid (Standard)** 3-Methylsulfanylpropionic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Fungal Endogenous Metabolite
3-(Methylthio)propionic acid (Standard) is the analytical standard of 3-(Methylthio)propionic acid. This product is intended for research and analytical applications. 3-(Methylthio)propionic acid is an intermediate in the methionine metabolism.

HY-W105506R

Dimethylpropiothetin hydrochloride (Standard) s,s-Dimethyl-β-propionic acid thetine (Standard)	Structural Classification Natural Products Gramineae Sporobolus anglicus (C.E.Hubb.) P.M.Peterson & Saarela Plants Source Classification	Reference Standards Endogenous Metabolite
Dimethylpropiothetin hydrochloride (Standard) is the analytical standard of Dimethylpropiothetin hydrochloride. This product is intended for research and analytical applications. Dimethylpropiothetin hydrochloride (s,s-Dimethyl-β-propionic acid thetine) is the hydrochloride form of dimethylpropiothetin. Dimethylpropiothetin can be isolated in marine algae, and is a precursor to dimethylsulfide (DMS). Dimethylpropiothetin is involved in osmoregulation in Hymenomonas carterae .

HY-W005255R

*3-(3-Hydroxyphenyl)propionic* acid (Standard)**	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Citrinin (Standard) is the analytical standard of Citrinin. This product is intended for research and analytical applications. Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity .

HY-W015346R

Desaminotyrosine (Standard) 3-(4-Hydroxyphenyl)propionic acid (Standard)	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Endogenous metabolite Source Classification	Reference Standards Influenza Virus Endogenous Metabolite
Apronal (Standard) is the analytical standard of Apronal. This product is intended for research and analytical applications. Apronal (Allylisopropylacetylurea, Apronalide) can bu used for the research of neuropsychiatry disorders.

HY-113158R

4-Hydroxyhippuric acid (Standard)	Immune System Disorder Disease markers Endogenous metabolite	Reference Standards Drug Metabolite
4-Hydroxyhippuric acid (Standard) is the analytical standard of 4-Hydroxyhippuric acid (HY-113158). This product is intended for research and analytical applications. 4-Hydroxyhippuric acid is a metabolite of polyphenols. 4-Hydroxyhippuric acid is generated via medium-chain acyl-CoA dehydrogenase (MCAD)-dependent β-oxidation of microbially-produced 3-(4-hydroxyphenyl)propionic acid, followed by host glycine conjugation. 4-Hydroxyhippuric acid can be simultaneously detected in urine as a biomarker of dietary polyphenol intake .

HY-W016482R

*3-(3-Methoxyphenyl)propionic* acid (Standard)**	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
3-(3-Methoxyphenyl)propionic acid is an organic acid, naturally occurring human metabolite and excreted in human urine.

Cat. No.	Product Name	Chemical Structure

HY-113371S

2-Methylcitric acid-d3

2-Methylcitric acid-d₃ is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-Y1088S2

Hydrocinnamic acid-d9
Hydrocinnamic acid-d₉ is the deuterium labeled Hydrocinnamic acid . Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activitie s.

HY-W105506S

Dimethylpropiothetin hydrochloride-d6
(2-Carboxyethyl)dimethylsulfonium-d₆ chloride is the deuterium labeled (2-Carboxyethyl)dimethylsulfonium chloride .

HY-Y1088S3

Hydrocinnamic acid-d5
Hydrocinnamic acid-d₅ is the deuterium labeled Hydrocinnamic acid . Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities .

HY-144418S

*DL-2-Amino-3-(hydroxy-amino)propionic* acid-15N**
DL-2-Amino-3-(hydroxy-amino)propionic acid- ¹⁵N is a ¹⁵N-labeled DL-2-Amino-3-(hydroxy-amino)propionic acid .

HY-Y1088S

Hydrocinnamic acid-2,3-13C2
Hydrocinnamic acid-2,3- ¹³C₂ is the ¹³C-labeled Hydrocinnamic acid. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.

HY-151084S

*3-(3-Ethoxy-4-methoxyphenyl)propionic-2,2,3,3-d4*
3-(3-Ethoxy-4-methoxyphenyl)propionic-2,2,3,3-d₄ is the deuterium labeled 3-(3-Ethoxy-4-methoxyphenyl)propionic .

HY-W015346S

Desaminotyrosine-d8
Desaminotyrosine-d₈ (3-(4-Hydroxyphenyl)propionic acid-d₈) is the deuterium labeled Desaminotyrosine (HY-W015346). Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.

Cat. No.	Product Name		Classification

HY-140102

*Azidoethyl-SS-propionic* NHS ester**		Azide ADC Synthesis
Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-136141

*DBCO-PEG3-propionic* EVCit-PAB**		ADC Synthesis DBCO
DBCO-PEG3-propionic EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-propionic EVCit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140100

*Azidoethyl-SS-propionic* acid**		Azide ADC Synthesis
Azidoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-136103

*DBCO-PEG4-Propionic-Val-Cit-PAB*		DBCO ADC Synthesis
DBCO-PEG4-Propionic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Propionic-Val-Cit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-W725327

1,2-Dipropionyl-sn-glycero-3-phosphocholine 1,2-Dipropionyl-sn-glycero-3-Phosphatidylcholine; 1,2-Dipropionyl-sn-glycero-3-Phosphocholine; PC(3:0/3:0)		Phospholipids
1,2-Dipropionyl-sn-glycero-3-PC is a phospholipid containing propionic acid at the sn-1 and sn-2 positions. It has been used to study the interaction between water and the phosphocholine headgroup in aqueous solutions.

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