Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
sAPP
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "sAPP" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W105970
CAS No.: 7758-16-9
Synonyms: Disodium pyrophosphate; Sodium acid pyrophosphate; sAPP
1
1 Cited Publications
Cat. No.: HY-P704352
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Pept
Species:
Human
Source:
HEK293
Cat. No.: HY-P1378A
Target:
Research Areas:
Synonyms: SQ 20009; EHT 0202 hydrochloride
Target:
Research Areas:
Etazolate hydrochloride (SQ 20009) is an orally active, selective inhibitor of type 4 phosphodiesterase (PDE4) with an IC50 of 2 μM. Etazolate hydrochloride is a γ-aminobutyric acid A (GABAA) receptor regulator. Etazolate hydrochloride is an α-secretase activator and induced the production of soluble amyloid precursor protein (sAPPα). Etazolate hydrochloride, a pyrazolopyridine class derivative, increases cAMP levels. Etazolate hydrochloride has anxiolyticlike, antidepressant-like and anti-inflammatory effects .
Cat. No.: HY-P1378
CAS No.: 134500-80-4
Target:
Research Areas:
Research Areas:
Sulfiram is a very weak aldehyde dehydrogenase (ALDH) inhibitor, with an IC50 value of 413 μM against Saccharomyces cerevisiae ALDH. As a photochemical precursor, Sulfiram undergoes photoconversion to form Disulfiram (HY-B0240), a potent ALDH inhibitor. Sulfiram inhibits the dimerization of the extracellular domain fragment (amino acid residues 230-624) of amyloid precursor protein (APP), alters the monomer-dimer equilibrium, induces conformational changes in the fragment, and enhances the production of sAPPα via α-cleavage of APP. Sulfiram can be used in research related to scabies and Alzheimer's disease .
Cat. No.: HY-118928
CAS No.: 412044-92-9
Synonyms: Demethyl-CHF 2819
Target:
Research Areas:
Demethyl-Ganstigmine hydrochloride (Demethyl-CHF 2819) is an orally active AChE inhibitor. Demethyl-Ganstigmine hydrochloride promotes the release of sAPPα from neuroblastoma cells. Demethyl-Ganstigmine hydrochloride increases the concentration of acetylcholine in the prefrontal cortex of rats. Demethyl-Ganstigmine hydrochloride is used in research on neurological diseases such as Alzheimer's disease .
Cat. No.: HY-100936R
CAS No.: 35838-58-5
Synonyms: SQ 20009 (Standard); EHT 0202 hydrochloride (Standard)
Research Areas:
Etazolate (hydrochloride) (Standard) is the analytical standard of Etazolate (hydrochloride). This product is intended for research and analytical applications. Etazolate hydrochloride (SQ 20009) is an orally active, selective inhibitor of type 4 phosphodiesterase (PDE4) with an IC50 of 2 μM. Etazolate hydrochloride is a γ-aminobutyric acid A (GABAA) receptor regulator. Etazolate hydrochloride is an α-secretase activator and induced the production of soluble amyloid precursor protein (sAPPα). Etazolate hydrochloride, a pyrazolopyridine class derivative, increases cAMP levels. Etazolate hydrochloride has anxiolyticlike, antidepressant-like and anti-inflammatory effects .
Cat. No.: HY-187132
CAS No.: 181139-85-5
Target:
Research Areas:
SIB-1281 is a β-secretase inhibitor that inhibits β-site cleavage of amyloid precursor protein (APP) and reduces the production of Aβ peptides. SIB-1281 decreases the generation of Aβ40 and Aβ42, and promotes the secretion of α-sAPP. SIB-1281 can be used in studies related to Alzheimer's disease .
Cat. No.: HY-118972
CAS No.: 1250849-11-6
Target:
Research Areas:
TPI-1917-49 is an agent that can cross the blood-brain barrier and reduce amyloid β (Aβ). TPI-1917-49 reduces the production of Aβ peptide segments by promoting the non-amyloidogenic pathway of amyloid precursor protein (APP) (increasing the generation of sAPPα mediated by α-secretase). TPI-1917-49 reduces amyloid plaques in mouse models. TPI-1917-49 can be used in Alzheimer's disease research .
Cat. No.: HY-P7501
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Pept
Species:
Human
Source:
HEK293
Cat. No.: HY-P72834
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Pept
Species:
Human
Source:
HEK293
Cat. No.: HY-P76168
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Pept
Species:
Human
Source:
E. coli
Cat. No.: HY-P704353
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Pept
Species:
Human
Source:
HEK293
Cat. No.: HY-P75511
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Pept
Species:
Human
Source:
E. coli
Cat. No.: HY-P706262
Purity: ≥ 95%, as determined by HPLC.
Synonyms: ¹⁵N-Beta-Amyloid Peptide(1-40); ¹⁵N-Aβ(1-40); ¹⁵N-Amyloid β Protein Fragment(1-40); ¹⁵N-Amyloid β-Peptide(1-40)(human); ¹⁵N-β-amyloid(1-40); APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Peptide(1-42); ABPP; Alternative Protein APP; Amyloid Beta (A4) Precursor Protein; Beta-Amyloid Peptide; Amyloid-Beta (A4) Precursor Protein; Amyloid Beta Protein; Alzheimer Disease Amyloid Protein; Alzheimer Disease; Cerebral Vascular Amyloid Peptide; CTFgamma; Amyloid Beta A4 Protein; ABETA; Amyloid-Beta A4 Protein; AAA; Peptidase Nexin-II; PN2; Protease Nexin-II; A4; PN-II; Amyloid Beta Precursor Protein; APPI
Species:
Human
Source:
E. coli
Cat. No.: HY-P706263
Purity: ≥ 95%, as determined by HPLC.
Synonyms: ¹⁵N,¹³C-Beta-Amyloid Peptide(1-40); ¹⁵N,¹³C-Aβ(1-40); ¹⁵N,¹³C-Amyloid β Protein Fragment(1-40); ¹⁵N,¹³C-Amyloid β-Peptide(1-40)(human); ¹⁵N,¹³C-β-amyloid(1-40); APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Peptide(1-42); ABPP; Alternative Protein APP; Amyloid Beta (A4) Precursor Protein; Beta-Amyloid Peptide; Amyloid-Beta (A4) Precursor Protein; Amyloid Beta Protein; Alzheimer Disease Amyloid Protein; Alzheimer Disease; Cerebral Vascular Amyloid Peptide; CTFgamma; Amyloid Beta A4 Protein; ABETA; Amyloid-Beta A4 Protein; AAA; Peptidase Nexin-II; PN2; Protease Nexin-II; A4; PN-II; Amyloid Beta Precursor Protein; APPI
Species:
Human
Source:
E. coli
Cat. No.: HY-P706264
Purity: ≥ 95%, as determined by HPLC.
Synonyms: ¹⁵N-Aβ(1-42); ¹⁵N-Beta-Amyloid(1-42); ¹⁵N-Aβ(1-42); ¹⁵N-Amyloid β Protein Fragment1-42; ¹⁵N-Amyloid β-Peptide(1-42); ¹⁵N-β-Amyloid 42; ¹⁵N-β-Amyloid(1-42); APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Peptide(1-42); ABPP; Alternative Protein APP; Amyloid Beta (A4) Precursor Protein; Beta-Amyloid Peptide; Amyloid-Beta (A4) Precursor Protein; Amyloid Beta Protein; Alzheimer Disease Amyloid Protein; Alzheimer Disease; Cerebral Vascular Amyloid Peptide; CTFgamma; Amyloid Beta A4 Protein; ABETA; Amyloid-Beta A4 Protein; AAA; Peptidase Nexin-II; PN2; Protease Nexin-II; A4; PN-II; Amyloid Beta Precursor Protein; APPI
Species:
Human
Source:
E. coli
Cat. No.: HY-P706265
Purity: ≥ 95%, as determined by HPLC.
Synonyms: ¹⁵N,¹³C-Aβ(1-42); ¹⁵N,¹³C-Beta-Amyloid(1-42); ¹⁵N,¹³C-Aβ(1-42); ¹⁵N,¹³C-Amyloid β Protein Fragment1-42; ¹⁵N,¹³C-Amyloid β-Peptide(1-42); ¹⁵N,¹³C-β-Amyloid 42; ¹⁵N,¹³C-β-Amyloid(1-42); APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease Amyloid A4 Protein Homolog; Beta-Amyloid Precursor Protein; Amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; Amyloid Precursor Protein; Beta-Amyloid Peptide(1-40); Alpha-sAPP; Beta-Amyloid Peptide(1-42); ABPP; Alternative Protein APP; Amyloid Beta (A4) Precursor Protein; Beta-Amyloid Peptide; Amyloid-Beta (A4) Precursor Protein; Amyloid Beta Protein; Alzheimer Disease Amyloid Protein; Alzheimer Disease; Cerebral Vascular Amyloid Peptide; CTFgamma; Amyloid Beta A4 Protein; ABETA; Amyloid-Beta A4 Protein; AAA; Peptidase Nexin-II; PN2; Protease Nexin-II; A4; PN-II; Amyloid Beta Precursor Protein; APPI
Species:
Human
Source:
E. coli
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
