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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
295 Results for "
saturated
" in MedChemExpress (MCE) Product Catalog:
Products (295)
295 Results for "saturated" in MCE Product Catalog:
124
124
19
19 Cited Publications
Target:
研究分野:
CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively.
CAY10566 also shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM) .
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7
4
4 Cited Publications
Target:
研究分野:
PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively .
3
3 Cited Publications
製品番号: HY-N2041S
CAS 番号: 60658-41-5
3
Target:
3
3 Cited Publications
製品番号: HY-W004284
CAS 番号: 506-12-7
3
3 Cited Publications
製品番号: HY-N0830BS1
CAS 番号: 2483736-17-8
3
3 Cited Publications
製品番号: HY-N0830S6
CAS 番号: 56599-85-0
3
3 Cited Publications
SCH529074 is a potent and orally active p53 activator. SCH529074 binds specifically and conformation-dependently to p53 DBD ( DNA binding domain) with a Ki of 1-2 μM in a saturable manner. SCH529074 restores mutant p53 function and interrupts HDM2-mediated ubiquitination of wild Type p53. SCH529074 can be used for the study of non-small-cell lung carcinoma (NSCLC) .
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Target:
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1
1 Cited Publications
製品番号: HY-W004283
CAS 番号: 1002-84-2
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1
Target:
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1
1 Cited Publications
製品番号: HY-B2219S2
CAS 番号: 287100-83-8
Stearic acid- 13C18is the 13C-labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
