Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
snakes
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "snakes" in MCE Product Catalog:
11
11 Cited Publications
Cat. No.: HY-P1902
CAS No.: 115722-23-1
Target:
11
11 Cited Publications
Cat. No.: HY-P1902A
CAS No.: 2918768-05-3
Target:
Cat. No.: HY-P1189
CAS No.: 154303-05-6
Target:
Category:
Plants Infection Flavonoids Deguelia rufescens (Benth.) R.A.Camargo & A.M.G.Azevedo Flavonones Phenols Polyphenols Compositae Extract Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-P1189A
Category:
Natural Products Animals Metabolic Disease Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-120078
CAS No.: 1845753-81-2
Target:
Research Areas:
AZD2716 is an orally active secretory phospholipase A2 (sPLA2) inhibitor. AZD2716 inhibits human GIIA sPLA2 (IC50=10 nM), human GV sPLA2 (IC50=40 nM), human GX sPLA2 (IC50=400 nM), snake venom sPLA2 (IC50=2 pM), and snake (Bothrops jararacussu) Lys49-PLA2-like toxin (Kd=110 μM). AZD2716 inhibits sPLA2 isoforms IIa, V, X, snake venom sPLA2s, and snake venom Lys49-PLA2-like toxin myotoxic activity via hydrophobic channel binding. AZD2716 suppresses GIIA sPLA2 production, neutralizes snake venom-induced myotoxicity, and improves survival in envenomed mice. AZD2716 can be used for the research of coronary artery disease, atherosclerosis, and snakebite envenoming .
Cat. No.: HY-W013741
CAS No.: 2491-17-0
Cat. No.: HY-B2119
CAS No.: 41945-48-6
Synonyms: Tauroglycocholic acid sodium salt
Target:
Research Areas:
Sodium tauroglycocholate (Tauroglycocholic acid sodium salt) is a multifunctional surfactant and penetration enhancer that can serve as a cholegraphic contrast agent. In organic solvents, Sodium tauroglycocholate embeds and stabilizes invertase by forming reverse micelles, and prolongs its active lifespan. In terms of transdermal absorption, Sodium tauroglycocholate effectively regulates the flux of aminophylline through snake slough by binding to keratin filaments, disrupting keratinocytes and altering lipid components of the stratum corneum. It exhibits rapid penetration characteristics without lag time at a concentration of 100 μg/mL. Sodium tauroglycocholate does not interfere with the hepatic uptake of Gd-EOB-DTPA by the bile acid transport system in rat hepatocytes .
Cat. No.: HY-P3269
CAS No.: 178805-91-9
Target:
Research Areas:
Cat. No.: HY-23909
CAS No.: 89560-01-0
Synonyms: DEDA
Target:
Research Areas:
7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA), a phospholipase inhibitor, is a non-metabolizable analog of arachidonic or eicosadienoic acid. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) inhibits P388D1 cell phospholipase A2 (PLA2) (IC50 = 16 µM) and snake venom PLA2 (IC50 = 14 µM) .
Cat. No.: HY-P11214
CAS No.: 2243975-43-9
Synonyms: H-TL1
Research Areas:
Cat. No.: HY-176241
Target:
Research Areas:
DC-174 is an orally active inhibitor of snake venom metalloproteinases (SVMP) with a broad spectrum of inhibitory activity against a variety of snake venom SVMPs. DC-174 acts directly on the active site of SVMPs via zinc-binding groups, inhibiting their enzymatic activity and procoagulant toxicity. DC-174 can significantly prolong the survival time of mice attacked by snake venom. DC-174 can be used in the study of first aid for snake bites .
Cat. No.: HY-N4016
CAS No.: 112137-81-2
Category:
Target:
Cat. No.: HY-P5835
CAS No.: 189201-23-8
Target:
Research Areas:
Cat. No.: HY-P10431
CAS No.: 1801534-21-3
Synonyms: Sea snake cathelicidin
Target:
Research Areas:
Cat. No.: HY-P5857
Synonyms: Micrurotoxin 2
Target:
Research Areas:
Cat. No.: HY-141555
CAS No.: 333409-31-7
Target:
Research Areas:
5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione is a weak inhibitor for snake venom and human recombinant phosphodiesterase 1 with IC50 of 429 and 467 μM. 5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione inhibits mushroom tyrosinase weakly, with Ki of 1.9 μM .
Cat. No.: HY-E70988
Target:
Research Areas:
Defibrase, Bothrops atrox snake is a fibrinogen-reducing agent with hemostatic properties and can be used in thrombosis research.
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
