24 Results for "

stretch

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "stretch" in MCE Product Catalog:

135
135 Publications Verification
Cat. No.: HY-P1410
CAS No.: 1209500-46-8
GsMTx4 is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
loading...
    loading...
135
135 Publications Verification
Cat. No.: HY-P1410A
GsMTx4 TFA is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
loading...
    loading...
51
51 Cited Publications
Cat. No.: HY-B1906
CAS No.: 57-92-1
Synonyms: Agrept; Agrimycin; Streptomycin A
Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-101848
CAS No.: 76343-94-7
Purity:  ≥98.0%
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P1235A
CAS No.: 1366000-58-9
Synonyms: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate
Target:  

Endothelin Receptor

Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-17484
CAS No.: 99464-64-9
Synonyms: CP 65703
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Ampiroxicam is an orally active prodrug of non-steroidal anti-inflammatory drug (NSAID). Ampiroxicam inhibits paw swelling in adjuvant-induced arthritis and acute inflammation models, and suppresses phenylbenzoquinone-induced stretching responses in mice. Ampiroxicam is rapidly and completely converted to Piroxicam (HY-B0253) via non-specific esterases and first-pass metabolism. Ampiroxicam induces contact hypersensitivity and photosensitivity reactions through photoproducts generated by UVA. Ampiroxicam can be used in research related to photosensitivity, adjuvant-induced arthritis, rheumatism, osteoarthritis and other inflammatory diseases .
loading...
    loading...
Cat. No.: HY-B1551
CAS No.: 104-31-4
Synonyms: Benzononatine
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Benzonatate (Benzononatine) is an orally active and non-narcotic peripheral antitussive agent. Benzonatate is a reversible voltage-gated Na + channels inhibitor. Benzonatate dampens the activity of cough stretch receptors .
loading...
    loading...
Cat. No.: HY-108482
CAS No.: 132746-60-2
CP-96,345 is a non-peptide selective NK-1 receptor antagonist (Ki = 0.31 nM). CP-96,345 inhibits cell rolling, adhesion, and plasma extravasation, and inhibits degranulation and pancreatic MPO activity. CP-96,345 attenuates neurogenic inflammation, edema, and adhesion molecule expression. CP-96,345 attenuates static contraction- and muscle stretch-evoked pressor reflexes through blockade of NK-1 receptors in the dorsal horn. CP-96,345 impairs post-ischemic recovery of LVDevP, HR, and CF in isolated hearts and increases reperfusion fibrillation. CP-96,345 can be used for research on chronic colitis, myocardial ischemia-reperfusion injury, smoke inhalation and burn injury, acute pancreatitis, oxazolone colitis, and neurogenic inflammation .
loading...
    loading...
Cat. No.: HY-P1519B
Synonyms: BNP (1-32), rat acetate
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes) .
loading...
    loading...
Cat. No.: HY-153840A
Purity:  97.03%
Research Areas:  

Inflammation/Immunology

ODN INH-18 sodium is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 sodium showes inhibitory potency for TLR9 ligand-induced IFN-α production.
loading...
    loading...
Cat. No.: HY-B1906R
CAS No.: 57-92-1
Synonyms: Agrept (Standard); Agrimycin (Standard); Streptomycin A (Standard)
Streptomycin (Standard) is the analytical standard of Streptomycin. This product is intended for research and analytical applications. Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
loading...
    loading...
Cat. No.: HY-P2736
CAS No.: 9012-56-0
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes .
loading...
    loading...
Cat. No.: HY-P1235
CAS No.: 89213-87-6
Synonyms: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine
Target:  

Endothelin Receptor

Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) inhibits endothelin-1 secretion in a dose-dependent way.
loading...
    loading...
Cat. No.: HY-P1519
CAS No.: 133448-20-1
Synonyms: BNP (1-32), rat
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

Brain Natriuretic Peptide (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes) .
loading...
    loading...
Cat. No.: HY-153840
CAS No.: 1934318-43-0
Research Areas:  

Inflammation/Immunology

ODN INH-18 is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 showes inhibitory potency for TLR9 ligand-induced IFN-α production.
loading...
    loading...
Cat. No.: HY-128418
CAS No.: 32760-16-0
Benzonatate (PEGn) is a unique non-narcotic antitussive agent that has sodium channel-blocking properties and anesthetic effects on the respiratory stretch receptors .
loading...
    loading...
Cat. No.: HY-P2590
CAS No.: 113611-68-0
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Tnrnflrfamide is a neuropeptide that modulates the receptor muscles of the lobster abdominal stretch receptors and their exoskeletal muscle homologues. Tnrnflrfamide enhances motor performance, including the amplitude of excitatory postsynaptic potentials and the development of nerve-evoked tension .
loading...
    loading...
Cat. No.: HY-B1551R
CAS No.: 104-31-4
Synonyms: Benzononatine (Standard)
Research Areas:  

Neurological Disease

Benzonatate (Standard) (Benzononatine (Standard)) is the analytical standard of Benzonatate (HY-B155). This product is intended for research and analytical applications. Benzonatate (Benzononatine) is an orally active and non-narcotic peripheral antitussive agent. Benzonatate is a reversible voltage-gated Na + channels inhibitor. Benzonatate dampens the activity of cough stretch receptors.
loading...
    loading...
Cat. No.: HY-156381
Research Areas:  

Others

Biotin-PEG3-CoenzymeA is a biotin-based, non-cell-permeable substrate with a PEG linker. Biotin-PEG3-CoenzymeA can generate biotinylated HaloTag-STReTCh-Biotin-GFP via Sfp synthase. Biotin-PEG3-CoenzymeA is applicable to studies related to biotinylation labeling of live cells .
loading...
    loading...
Cat. No.: HY-153840B
Research Areas:  

Inflammation/Immunology

ODN INH-18 triethylamine is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 triethylamine showes inhibitory potency for TLR9 ligand-induced IFN-α production.
loading...
    loading...