43 Results for "

synthetic peptide substrate

" in MedChemExpress (MCE) Product Catalog:
Products (43)

43 Results for "synthetic peptide substrate" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P1821
CAS No.: 126768-94-3
Synonyms: MHP4-14
Target:  

PKC

Research Areas:  

Neurological Disease

Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca 2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .
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2
2 Cited Publications
Cat. No.: HY-P1821A
Synonyms: MHP4-14 TFA
Target:  

PKC

Research Areas:  

Neurological Disease

Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca 2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .
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1
1 Cited Publications
Cat. No.: HY-139201A
CAS No.: 27964-99-4
Synonyms: PDLHB (MW 70000-150000)
Poly-D-lysine hydrobromide (MW 70000-150000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .
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1
1 Cited Publications
Cat. No.: HY-P2171A
Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

CCP peptide TFA is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide TFA functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA) .
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Cat. No.: HY-139201
CAS No.: 27964-99-4
Synonyms: PDLHB (MW 30000-70000)
Target:  

CaSR

Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .
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Cat. No.: HY-131498
CAS No.: 140430-53-1
Purity:  99.67%
Synonyms: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2
Target:  

Fluorescent Dye MMP

Research Areas:  

Cancer

MOCAc-PLGL (Dpa) AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) is a synthetic fluorescent substrate mainly used for in vitro enzymatic activity assays of MMP-7 (detection at 393 nm after excitation at 328 nm). MOCAc-PLGL (Dpa) AR is specifically cleaved and hydrolyzed by MMP-7 at the Gly-Leu peptide bond, allowing enzymatic activity to be monitored via fluorometry or HPLC (DMSO is usually added to ensure sufficient dissolution when determining kinetic parameters). MOCAc-PLGL (Dpa) AR is used to accurately evaluate the catalytic activity and pH dependence of recombinant mature human MMP-7 in vitro. MOCAc-PLGL (Dpa) AR is suitable for research on the mechanisms of tumor metastasis and invasion, particularly in fields such as prostate cancer, colon cancer, lung cancer and breast cancer .\n
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Cat. No.: HY-139201B
CAS No.: 27964-99-4
Synonyms: PDLHB (MW 84000)
Target:  

CaSR

Research Areas:  

Neurological Disease Cancer

Poly-D-lysine hydrobromide (MW 84000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .
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Cat. No.: HY-P6028A
Research Areas:  

Others

GSNKSKPK-NH2 TFA is a synthetic model peptide based on the c-Src N-terminal sequence and model peptide substrate for human NMT1 and NMT2.GSNKSKPK-NH2 TFA facilitates in vitro assays measuring transfer of myristate or X10 fatty acid moieties .
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Cat. No.: HY-P1595
CAS No.: 149155-45-3
Target:  

PKA PKC

Research Areas:  

Metabolic Disease

CREBtide is a CREB (cAMP response element binding protein)-like peptide. CREBtide, a synthetic 13 amino acid peptide, has been reported as a PKA and PKC substrate.
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Cat. No.: HY-Y0837
CAS No.: 2749-11-3
Synonyms: (S)-2-Amino-1-propanol; (S)-2-Aminopropanol; (S)-Alaninol
L-Alaninol ((S)-2-Amino-1-propanol; (S)-2-Aminopropanol; (S)-Alaninol) is a chiral amino alcohol that serves as a precursor for Levofloxacin (HY-B0330) and Metolachlor (HY-B1871). L-Alaninol acts as the sole carbon source for Pseudomonas sp. strain KIE171, and it is a metabolite produced by the hydrolysis of γ-glutamyl-L-alaninol. L-Alaninol functions as a substrate for oxidative/deaminative degradation and undergoes enzymatic glutamylation via IpuC. It is used as a synthetic building block in the fields of agriculture, pharmaceuticals, and peptide chemistry, and also serves as a chiral auxiliary .
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Cat. No.: HY-P5278
CAS No.: 130698-88-3
Target:  

Ser/Thr Protease

Research Areas:  

Others

Z-Gly-Arg-Thiobenzyl ester is a synthetic peptide substrate used to detect the cleavage activity of C1r. Z-Gly-Arg-Thiobenzyl ester can be cleaved by proteases such as C1r, and when used in combination with DTNB (HY-15915) , it enables colorimetric determination of protease activity, which can be applied to enzymological studies related to the complement system .
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Cat. No.: HY-W098322
CAS No.: 26348-68-5
Target:  

Drug Intermediate

Research Areas:  

Others

Z-Lys-OMe hydrochloride is a synthetic intermediate that can be used in the synthesis of peptide enzyme substrates and lysine cationic surfactants.
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Cat. No.: HY-P1576A
Target:  

AMPK SnRK

Research Areas:  

Others

AMARA peptide TFA is a synthetic peptide substrate of sucrose non-fermenting-1-related protein kinase 1 (SnRK1). AMARA peptide TFA contains residues required for SnRK1 phosphorylation, retains the minimal motif recognized by SnRK1, and when this substrate is recognized by cauliflower SnRK1 HRK-A, the hydrophobic residues at the relative positions P-5 and P+4 of the phosphorylated serine require a critical spacing. AMARA peptide TFA can serve as a control substrate in peptide phosphorylation assays for the detection of SnRK1 activity in Arabidopsis thaliana, potato tuber tissues, and during SnRK1 purification .
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Cat. No.: HY-P5485
CAS No.: 271798-75-5
Target:  

Bacterial

Research Areas:  

Others

Dabcyl-QALPETGEE-Edans is a synthetic peptide substrate for fluorescence resonance energy transfer (FRET) detection of Sortase A (SrtA) enzymatic activity. Dabcyl-QALPETGEE-Edans is labeled at both ends with the fluorescent group Edans (donor) and the quencher Dabcyl (acceptor), respectively. Dabcyl-QALPETGEE-Edans's central sequence contains a conserved motif specifically recognized by SrtA. Dabcyl-QALPETGEE-Edans demonstrates high sensitivity in vitro assays, enabling precise determination of the half-maximal inhibitory concentration of SrtA .
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Cat. No.: HY-P2171
CAS No.: 277748-59-1
Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

CCP peptide is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA) .
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Cat. No.: HY-Y0837S
CAS No.: 352438-84-7
Synonyms: (S)-2-Amino-1-propanol-d3; (S)-2-Aminopropanol-d3; (S)-Alaninol-d3
L-Alaninol-d3 ((S)-2-Amino-1-propanol-d3; (S)-2-Aminopropanol-d3; (S)-Alaninol-d3) is the deuterated-labeled L-Alaninol (HY-Y0837). L-Alaninol ((S)-2-Amino-1-propanol; (S)-2-Aminopropanol; (S)-Alaninol) is a chiral amino alcohol that serves as a precursor for Levofloxacin (HY-B0330) and Metolachlor (HY-B1871). L-Alaninol acts as the sole carbon source for Pseudomonas sp. strain KIE171, and it is a metabolite produced by the hydrolysis of γ-glutamyl-L-alaninol. L-Alaninol functions as a substrate for oxidative/deaminative degradation and undergoes enzymatic glutamylation via IpuC. It is used as a synthetic building block in the fields of agriculture, pharmaceuticals, and peptide chemistry, and also serves as a chiral auxiliary .
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Cat. No.: HY-P1344A
Target:  

DAPK

Research Areas:  

Cancer

DAPK Substrate Peptide TFA is a synthetic peptide substrate for death associated protein kinase (DAPK), with a Km of 9 μM .
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Cat. No.: HY-138143
CAS No.: 86890-95-1
Synonyms: Chromozym-TH
Target:  

Fluorescent Dye

Research Areas:  

Others

N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V) .
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Cat. No.: HY-P6028
Research Areas:  

Others

GSNKSKPK-NH2 is a synthetic model peptide based on the c-Src N-terminal sequence and model peptide substrate for human NMT1 and NMT2.GSNKSKPK-NH2 facilitates in vitro assays measuring transfer of myristate or X10 fatty acid moieties .
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Cat. No.: HY-P0248F
CAS No.: 1161072-61-2
Target:  

PKA Fluorescent Dye

Research Areas:  

Metabolic Disease

Kemptide, 5-FAM labeled is a 5-FAM labeled Kemptide (HY-P0248). Kemptide is a phosphate acceptor peptide that serves as a synthetic substrate for PKA (Km = 16 μM). The corresponding fluorescent and biotinylated peptides are also proven to be good substrates for PKA.
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