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synthetic peptide substrate

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製品番号 製品名 Target 研究分野 構造式
  • HY-139201A
    Poly-D-lysine hydrobromide (MW 70000-150000)
    1 Publications Verification

    PDLHB (MW 70000-150000)

    		 Biochemical Assay Reagents CaSR Neurological Disease Cancer
    Poly-D-lysine hydrobromide (MW 70000-150000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .
    Poly-D-lysine hydrobromide (MW 70000-150000)
  • HY-139201
    Poly-D-lysine hydrobromide (MW 30000-70000)

    PDLHB (MW 30000-70000)

    		 CaSR Neurological Disease Metabolic Disease Cancer
    Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .
    Poly-D-lysine hydrobromide (MW 30000-70000)
  • HY-131498
    MOCAc-PLGL(Dpa)AR

    Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2

    		 Fluorescent Dye MMP Cancer
    MOCAc-PLGL (Dpa) AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) is a synthetic fluorescent substrate mainly used for in vitro enzymatic activity assays of MMP-7 (detection at 393 nm after excitation at 328 nm). MOCAc-PLGL (Dpa) AR is specifically cleaved and hydrolyzed by MMP-7 at the Gly-Leu peptide bond, allowing enzymatic activity to be monitored via fluorometry or HPLC (DMSO is usually added to ensure sufficient dissolution when determining kinetic parameters). MOCAc-PLGL (Dpa) AR is used to accurately evaluate the catalytic activity and pH dependence of recombinant mature human MMP-7 in vitro. MOCAc-PLGL (Dpa) AR is suitable for research on the mechanisms of tumor metastasis and invasion, particularly in fields such as prostate cancer, colon cancer, lung cancer and breast cancer .\n
    MOCAc-PLGL(Dpa)AR
  • HY-P1821
    Myelin Basic Protein
    2 Publications Verification

    MHP4-14

    		 PKC Neurological Disease
    Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca 2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .
    Myelin Basic Protein
  • HY-139201B
    Poly-D-lysine hydrobromide (MW 84000)

    PDLHB (MW 84000)

    		 CaSR Neurological Disease Cancer
    Poly-D-lysine hydrobromide (MW 84000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .
    Poly-D-lysine hydrobromide (MW 84000)
  • HY-P6028A
    GSNKSKPK-NH2 TFA

    		N-myristoyltransferase Others
    GSNKSKPK-NH2 TFA is a synthetic model peptide based on the c-Src N-terminal sequence and model peptide substrate for human NMT1 and NMT2.GSNKSKPK-NH2 TFA facilitates in vitro assays measuring transfer of myristate or X10 fatty acid moieties .
    GSNKSKPK-NH2 TFA
  • HY-137199
    Pro-Phe-Arg-AMC

    		Biochemical Assay Reagents Others
    Pro-Phe-Arg-AMC is a synthetic peptide substrate of Cysteine peptidases (CPs) .
    Pro-Phe-Arg-AMC
  • HY-P1595
    CREBtide

    		PKA PKC Metabolic Disease
    CREBtide is a CREB (cAMP response element binding protein)-like peptide. CREBtide, a synthetic 13 amino acid peptide, has been reported as a PKA and PKC substrate.
    CREBtide
  • HY-W098322
    Z-Lys-OMe hydrochloride

    		Drug Intermediate Others
    Z-Lys-OMe hydrochloride is a synthetic intermediate that can be used in the synthesis of peptide enzyme substrates and lysine cationic surfactants.
    Z-Lys-OMe hydrochloride
  • HY-P5485
    Dabcyl-QALPETGEE-Edans

    		Bacterial Others
    Dabcyl-QALPETGEE-Edans is a synthetic peptide substrate for fluorescence resonance energy transfer (FRET) detection of Sortase A (SrtA) enzymatic activity. Dabcyl-QALPETGEE-Edans is labeled at both ends with the fluorescent group Edans (donor) and the quencher Dabcyl (acceptor), respectively. Dabcyl-QALPETGEE-Edans's central sequence contains a conserved motif specifically recognized by SrtA. Dabcyl-QALPETGEE-Edans demonstrates high sensitivity in vitro assays, enabling precise determination of the half-maximal inhibitory concentration of SrtA .
    Dabcyl-QALPETGEE-Edans
  • HY-P1821A
    Myelin basic protein (4-14) TFA
    2 Publications Verification

    MHP4-14 TFA

    		 PKC Neurological Disease
    Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca 2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .
    Myelin basic protein (4-14) TFA
  • HY-P1344A
    DAPK Substrate Peptide TFA

    		DAPK Cancer
    DAPK Substrate Peptide TFA is a synthetic peptide substrate for death associated protein kinase (DAPK), with a Km of 9 μM .
    DAPK Substrate Peptide TFA
  • HY-138143
    N-(p-Tosyl)-GPR-pNA acetate

    Chromozym-TH

    		 Fluorescent Dye Others
    N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V) .
    N-(p-Tosyl)-GPR-pNA acetate
  • HY-P6028
    GSNKSKPK-NH2

    		N-myristoyltransferase Others
    GSNKSKPK-NH2 is a synthetic model peptide based on the c-Src N-terminal sequence and model peptide substrate for human NMT1 and NMT2.GSNKSKPK-NH2 facilitates in vitro assays measuring transfer of myristate or X10 fatty acid moieties .
    GSNKSKPK-NH2
  • HY-P0248F
    Kemptide, 5-FAM labeled

    		PKA Fluorescent Dye Metabolic Disease
    Kemptide, 5-FAM labeled is a 5-FAM labeled Kemptide (HY-P0248). Kemptide is a phosphate acceptor peptide that serves as a synthetic substrate for PKA (Km = 16 μM). The corresponding fluorescent and biotinylated peptides are also proven to be good substrates for PKA.
    Kemptide, 5-FAM labeled
  • HY-P10082
    Ac-VETD-AMC

    		Caspase Others
    Ac-VETD-AMC is a synthetic peptide substrate for caspase 8. Ac-VETD-AMC also has potential to assess functional activity of recombinant phytaspase .
    Ac-VETD-AMC
  • HY-P1344
    DAPK Substrate Peptide

    		DAPK Cancer
    DAPK Substrate Peptide is a synthetic peptide substrate for death associated protein kinase (DAPK), with a Km of 9 μM .
    DAPK Substrate Peptide
  • HY-P3944
    Calmodulin Dependent Protein Kinase Substrate

    		CaMK Neurological Disease
    Calmodulin Dependent Protein Kinase Substrate is a Ca 2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. Calmodulin Dependent Protein Kinase Substrate is a synthetic peptide substrate for protein kinases .
    Calmodulin Dependent Protein Kinase Substrate
  • HY-P0141
    Akt/SKG Substrate Peptide

    		Akt Others
    Akt/SKG Substrate Peptide is a synthetic peptide suitable as a substrate for Akt/PKB, which is not phosphorylated by p70S6K or MAPK1 .
    Akt/SKG Substrate Peptide
  • HY-P3943
    Calmodulin Dependent Protein Kinase Substrate Analog

    		CaMK Neurological Disease
    Calmodulin Dependent Protein Kinase Substrate Analog is a Ca 2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. Calmodulin Dependent Protein Kinase Substrate Analog is a synthetic peptide substrate for protein kinases .
    Calmodulin Dependent Protein Kinase Substrate Analog
  • HY-P5385
    Renin substrate, angiotensinogen (1-14), rat

    		Angiotensin Receptor Others
    Renin substrate, angiotensinogen (1-14), rat is a biological active peptide. (This peptide is derived from rat angiotensinogen amino acid residues 1-14. It is a synthetic renin substrate.)
    Renin substrate, angiotensinogen (1-14), rat
  • HY-P0141A
    Akt/SKG Substrate Peptide TFA

    		Akt Others
    Akt/SKG Substrate Peptide TFA is a synthetic peptide suitable as a substrate for Akt/PKB, which is not phosphorylated by p70S6K or MAPK1 .
    Akt/SKG Substrate Peptide TFA
  • HY-P5998
    Myosin Light Chain Kinase Substrate (smooth muscle)

    		Myosin Cancer
    Myosin Light Chain Kinase Substrate (smooth muscle) is a smooth muscle myosin light chain kinase (MLCK) synthetic peptide substrate .
    Myosin Light Chain Kinase Substrate (smooth muscle)
  • HY-P4514
    Z-Gly-Gly-Arg-βNA

    		Proteasome Others
    Z-Gly-Gly-Arg-βNA is the synthetic peptide substrate of trypsin-like activities of the proteasome .
    Z-Gly-Gly-Arg-βNA
  • HY-P1595A
    CREBtide TFA

    		PKA PKC Metabolic Disease
    CREBtide TFA is a CREB (cAMP response element binding protein)-like peptide. CREBtide TFA a synthetic 13 amino acid peptide, has been reported as a PKA and PKC substrate .
    CREBtide TFA
  • HY-P3904
    P34cdc2 Kinase Substrate Peptide

    		Biochemical Assay Reagents Others
    P34cdc2 Kinase Substrate Peptide is a synthetic peptide substrates for P34 cdc2 kinase, with a Km of 74 μM for the purified human enzyme. P34cdc2 Kinase Substrate Peptide can be used in a rapid assay of P34 cdc2 phosphorylation in vitro. P34 cdc2, a protein serinehhreonine kinase, is a cell division cycle-regulated protein kinase .
    P34cdc2 Kinase Substrate Peptide
  • HY-P4038
    Hepatitis C Virus S5A/5B

    		HCV Protease Infection
    Hepatitis C Virus S5A/5B is a synthetic peptide substrate. Hepatitis C Virus S5A/5B mimics the NS5A/5B junction of the nonstructural protein (NS), served as the substrate for the study of HCV NS3 protease activity .
    Hepatitis C Virus S5A/5B
  • HY-P2651
    Dansyl-D-Ala-Gly-Phe(pNO2)-Gly

    		Fluorescent Dye Others
    Dansyl-D-Ala-Gly-Phe(pNO2)-Gly is a synthetic peptide substrate. As a substrate of NEP, Dansyl-D-Ala-Gly-Phe(pNO2)-Gly can be specifically recognized and cleaved by the enzyme, thereby releasing the fluorophore dansyl, which can be quantitatively detected. Therefore, it is often used to determine the activity of NEP .
    Dansyl-D-Ala-Gly-Phe(pNO2)-Gly
  • HY-P10574
    Phosphorylated CHKtide

    		Checkpoint Kinase (Chk) Cancer
    Phosphorylated CHKtide is a synthetic peptide substrate derived from CDC25C, which is phosphorylated by CHK1/CHK2 in one of the DNA repair pathways. Phosphorylated CHKtide is used in the assays of cell cycle checkpoint kinases 1 and 2 (CHK1/CHK2) and salt-inducible kinases (SIKs) .
    Phosphorylated CHKtide
  • HY-W927376
    Boc-Val-Arg-AMC

    		Fluorescent Dye Others
    Boc-Val-Arg-AMC is a synthetic peptide compound. As a specific fluorescent substrate, Boc-Val-Arg-AMC can be specifically cleaved by specific enzymes, especially thrombin, to release a fluorescent molecule AMC (7-amino-4-methylcoumarin), which can be used to monitor thrombin activity. Boc-Val-Arg-AMC can be used to detect thrombin activity in plasma samples .
    Boc-Val-Arg-AMC
  • HY-P11034
    BPDEtide

    		PKG Inflammation/Immunology
    BPDEtide is a synthetic peptide. BPDEtide has apparent Km values of 68 and 320 μM for cGK and cAK, respectively. BPDEtide is the most selective peptide substrate for measuring cGK activity .
    BPDEtide
  • HY-E71017
    Proteinase A, baker's yeast (S. cerevisiae)

    		Biochemical Assay Reagents Metabolic Disease
    Proteinase A, from baker's yeast (S. cerevisiae) (EC 3.4.23.25), hydrolyzes proteins and exhibits broad specificity for peptide bonds. Proteinase A can cleave the leucine-leucine-valine-tyrosine bonds in synthetic substrates.
    Proteinase A, baker's yeast (S. cerevisiae)

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