Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
tactile
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "tactile" in MCE Product Catalog:
Target:
Research Areas:
A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo .
Synonyms: EMD 281014 free base; LY 2422347
Target:
Research Areas:
Pruvanserin (EMD 281014 free base) is a selective 5-HT2A receptor antagonist. Pruvanserin alleviates tactile allodynia in diabetic rats. Pruvanserin can also be used for research of insomnia .
Cat. No.: HY-110099
CAS No.: 473722-68-8
Target:
Research Areas:
(±)-NBI-74330 is a potent and selective CXCR3 antagonist. (±)-NBI-74330 not only reduces tactile and thermal hypersensitivity but also enhances the analgesic properties of morphine. (±)-NBI-74330 can reduce microglial cell activation, increase astroglial cell activation, and downregulate the expression of some CXCR3 ligands in a rat neuropathic pain model .
Cat. No.: HY-114901
CAS No.: 186141-75-3
Target:
Research Areas:
A-134974 is a selective adenosine kinase (ADK) inhibitor, with an IC50 of 0.06 nM and 45 nM in rat brain cytoplasmic ADK enzyme assays and intact IMR-32 cells, respectively . A-134974 inhibits adenosine phosphorylation and elevates intracellular and extracellular adenosine levels, alleviates neuropathic tactile allodynia and inflammatory thermal hyperalgesia via endogenous adenosine signaling in the spinal cord, and shows favorable dose separation between its analgesic effects and motor function impairment . A-134974 can be used in research on neuropathic pain, inflammatory pain, RNA silencing and thermoregulation .
Cat. No.: HY-P10767
CAS No.: 2468971-42-6
Target:
Research Areas:
Cat. No.: HY-168333
CAS No.: 2727088-38-0
Target:
Research Areas:
5-HT6 inverse agonist 1 (Compound 33) is an antagonist for 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. 5-HT6 inverse agonist 1 inhibits the 5-HT6R mediated Cdk5 and mTOR signaling pathway. 5-HT6 inverse agonist 1 reduces tactile hypersensitivity in spinal nerve ligation (SNL)-induced rat model .
Cat. No.: HY-146280
CAS No.: 2556833-57-7
Target:
Research Areas:
mGAT3/4-IN-1 (compound 19b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.31 and 5.24, respectively. mGAT3/4-IN-1 exhibits a significant tactile allodynia reduction in diabetic neuropathic mice .
Cat. No.: HY-RS02279
Target:
Research Areas:
CD96 Human Pre-designed siRNA Set A contains three designed siRNAs for CD96 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18232
Target:
Research Areas:
Cd96 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd96 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-146281
CAS No.: 2556833-68-0
Target:
Research Areas:
mGAT3/4-IN-2 (compound 27b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.44 and 5.25, respectively .
Cat. No.: HY-100080R
CAS No.: 1266212-81-0
Target:
Research Areas:
A-887826 (Standard) is the analytical standard of A-887826 (HY-100080). This product is intended for research and analytical applications. A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo .
Cat. No.: HY-P700686
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD96 molecule; CD96; DKFZp667E2122; tactile
Species:
Source:
Cat. No.: HY-P700855
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD96 molecule; CD96; DKFZp667E2122; tactile
Cat. No.: HY-106246R
CAS No.: 443144-26-1
Synonyms: EMD 281014 free base (Standard); LY 2422347 (Standard)
Target:
Research Areas:
Pruvanserin (Standard) is the analytical standard of Pruvanserin (HY-106246). This product is intended for research and analytical applications. Pruvanserin (EMD 281014 free acid) is a selective 5-HT2A receptor antagonist. Pruvanserin alleviates tactile allodynia in diabetic rats. Pruvanserin can also be used for research of insomnia .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
