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Results for "

vasoconstrictive

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (4) Adrenergic Receptor (6) Akt (2) Angiotensin Receptor (1) Apoptosis (3) Bcl-2 Family (2) Calcium Channel (2) Drug Derivative (1) Endogenous Metabolite (1) Endothelin Receptor (1) Glucocorticoid Receptor (5) Glutamate Dehydrogenase (GLDH) (1) Imidazoline Receptor (1) Isotope-Labeled Compounds (4) Potassium Channel (7) Prostaglandin Receptor (1) Reactive Oxygen Species (ROS) (1) Reference Standards (8) ROCK (1) Sodium Channel (8) β-glucuronidase (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (23) Endocrinology (1) Inflammation/Immunology (8) Neurological Disease (14)

By Targets:

5-HT Receptor (4)

Adrenergic Receptor (6)

Akt (2)

Angiotensin Receptor (1)

Apoptosis (3)

Bcl-2 Family (2)

Calcium Channel (2)

Drug Derivative (1)

Endogenous Metabolite (1)

Endothelin Receptor (1)

Glucocorticoid Receptor (5)

Glutamate Dehydrogenase (GLDH) (1)

Imidazoline Receptor (1)

Isotope-Labeled Compounds (4)

Potassium Channel (7)

Prostaglandin Receptor (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (8)

ROCK (1)

Sodium Channel (8)

β-glucuronidase (1)

By Research Areas:

Cancer (9)

Cardiovascular Disease (23)

Endocrinology (1)

Inflammation/Immunology (8)

Neurological Disease (14)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10588

Bay K 8644 Maximum Cited Publications 8 Publications Verification (±)-Bay K 8644	Calcium Channel	Cardiovascular Disease Neurological Disease
Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644 . Bay K 8644 is a L-type Ca ²⁺ channel agonist with an EC₅₀ of 17.3 nM. Bay K 8644 increases Ca ²⁺ influx through sarcolemmal Ca ²⁺ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects .

HY-B0563

Ropivacaine 5+ Cited Publications	Sodium Channel Potassium Channel	Cardiovascular Disease Neurological Disease Cancer
Ropivacain is a potent sodium channel blocker. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is used for the research of neuropathic pain management .

HY-B0206

Rizatriptan benzoate MK 462	5-HT Receptor	Neurological Disease
Rizatriptan benzoate is the agonist for 5-HT_1B and 5-HT_1D. Rizatriptan benzoate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system .

HY-B0563B

Ropivacaine hydrochloride 5+ Cited Publications	Sodium Channel Potassium Channel	Cardiovascular Disease Neurological Disease Cancer
Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for neuropathic pain management in vivo .

HY-N0757

8-O-Acetylharpagide 1 Publications Verification	Akt Bcl-2 Family Apoptosis Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
8-O-Acetylharpagide is an orally active iridoid glycoside compound. 8-O-Acetylharpagide exhibits anti-aging activity at low doses and anticancer activity at high doses. 8-O-Acetylharpagide induces late-stage apoptosis and necrosis-like death in cancer cells, and downregulates anti-apoptotic proteins such as Akt, p-Akt and Bcl-2. 8-O-Acetylharpagide is mainly metabolized in rats via demethylation, hydrolysis and glucuronidation, and its active metabolites downregulate the AKT/NF-κB/MMP9 signaling axis. 8-O-Acetylharpagide exerts vasoconstrictive effects by activating vascular α-adrenoceptor .

HY-B0878

Halobetasol propionate 1 Publications Verification BMY-30056; CGP-14458; Ulobetasol propionate	Glucocorticoid Receptor	Inflammation/Immunology
Halobetasol propionate (BMY-30056) is a synthetic glucocorticoid corticosteroid. Halobetasol propionate exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties. Halobetasol propionate can be used for the study of psoriasis .

HY-113248

3-Nitro-L-tyrosine	Endogenous Metabolite Adrenergic Receptor Reactive Oxygen Species (ROS)	Cardiovascular Disease Inflammation/Immunology
3-Nitro-L-tyrosine serves as a biomarker of oxidative stress. 3-Nitro-L-tyrosine attenuates the pressor and vasoconstrictive effects of angiotensin II by inhibiting the α₁-adrenergic receptor-mediated signaling pathway, and participates in hemodynamic regulation under pathological conditions such as inflammation and ischemia. 3-Nitro-L-tyrosine can be used in studies related to atherosclerosis, ischemia-reperfusion and sepsis .

HY-B0563A

Ropivacaine hydrochloride monohydrate 5+ Cited Publications	Sodium Channel Potassium Channel	Cardiovascular Disease Neurological Disease Cancer
Ropivacaine hydrochloride monohydrate is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for regional anesthesia and neuropathic pain management in vivo .

HY-B1052

Lofexidine hydrochloride Baq-168; MDL-14042	Adrenergic Receptor Imidazoline Receptor	Neurological Disease
Lofexidine hydrochloride (Baq-168) is an orally active agonist of the imidazoline I1 receptor (imidazoline I1 receptor) (Ki: 1.9 nM) and α₂-adrenergic receptor (α2-adrenergic receptor). Lofexidine hydrochloride binds to the α₂A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. It regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine hydrochloride is applicable to research on opioid addiction and withdrawal .

HY-107949

Flumethasone pivalate Flumethasone 21-pivalate	Glucocorticoid Receptor	Cardiovascular Disease Inflammation/Immunology
Flumethasone pivalate (Flumethasone 21-pivalate) is a glucocorticoid and a topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive actions. Flumethasone pivalate inhibits foreign body granuloma formation. Flumethasone pivalate can be used for the researches of dermatitis, eczema, and psoriasis .

HY-119961

(+)-Mepivacaine Dexivacaine; (S)-Mepivacaine	Sodium Channel	Cardiovascular Disease
(+)-Mepivacaine is a racemic isomer of Mepivacaine (HY-B0517), which has analgesic and vasoconstrictive activity. Mepivacaine is an amide type agent that temporarily causes local loss of consciousness. Mepivacaine binds to specific voltage-gated sodium channels on neuronal cell membranes, inhibiting sodium influx and membrane depolarization .

HY-105697

Protoveratrine A NSC 7526; Protalba; Protoveratrin	Glutamate Dehydrogenase (GLDH)	Cardiovascular Disease
Protoveratrine A (NSC 7526; Protalba; Protoveratrin) is an alkaloid with strong cardiostimulant and vasoconstrictive effects, which can be used in the study of hypertension and other cardiovascular diseases .

HY-B0878R

Halobetasol propionate (Standard) 1 Publications Verification BMY-30056 (Standard); CGP-14458 (Standard); Ulobetasol propionate (Standard)	Reference Standards Glucocorticoid Receptor	Inflammation/Immunology
Halobetasol propionate (Standard) (BMY-30056 (Standard)) is the analytical standard of Halobetasol propionate (HY-B0878). This product is intended for research and analytical applications. Halobetasol propionate (BMY-30056) is a synthetic glucocorticoid corticosteroid. Halobetasol propionate exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties. Halobetasol propionate can be used for the study of psoriasis .

HY-B0206R

Rizatriptan benzoate (Standard) MK 462 (Standard)	Reference Standards 5-HT Receptor	Neurological Disease
Rizatriptan (benzoate) (Standard) is the analytical standard of Rizatriptan (benzoate). This product is intended for research and analytical applications. Rizatriptan benzoate is the agonist for 5-HT_1B and 5-HT_1D. Rizatriptan benzoate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system .

HY-130448

8-iso Prostaglandin F1β	Prostaglandin Receptor ROCK	Cardiovascular Disease
8-iso Prostaglandin F1β is an isoprostane, that exhibits vasoconstrictive effect in neonatal porcine pulmonary arteries, pulmonary veins, and mesenteric arteries. 8-iso Prostaglandin F1β targets TXA2 receptor and exhibits the blood vessel contractile efficacy under the influence of tyrosine kinase and Rho kinase .

HY-107949R

Flumethasone pivalate (Standard) Flumethasone 21-pivalate (Standard)	Glucocorticoid Receptor Reference Standards	Cardiovascular Disease Inflammation/Immunology
Flumethasone pivalate (Flumethasone 21-pivalate) (Standard) is the analytical standard of Flumethasone pivalate (HY-107949). This product is intended for research and analytical applications. Flumethasone pivalate is a glucocorticoid and a topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive actions. Flumethasone pivalate inhibits foreign body granuloma formation. Flumethasone pivalate can be used for the researches of dermatitis, eczema, and psoriasis .

HY-W018475B

Rizatriptan hemisulfate hemihydrate MK 462 hemisulfate hemihydrate	5-HT Receptor	Neurological Disease
Rizatriptan (MK 462) hemisulfate hemihydrate is the agonist for 5-HT_1B and 5-HT_1D. Rizatriptan hemisulfate hemihydrate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system .

HY-U00075

Indanazoline	Drug Derivative	Cardiovascular Disease
Indanazoline (as monohydrochloride active substance of Farial) is characterized by a pronounced vasoconstrictive action.

HY-W014726

DL-Phenylephrine hydrochloride (±)-Phenylephrine hydrochloride	Adrenergic Receptor	Cardiovascular Disease
DL-Phenylephrine ((±)-Phenylephrine) hydrochloride is a selective agonist of the alpha1-adrenergic receptor, exhibiting potent vasoconstrictive activity.

HY-N9271R

Grifolin (Standard)	Apoptosis Reference Standards	Cancer
Flumethasone pivalate (Standard) is the analytical standard of Flumethasone pivalate. This product is intended for research and analytical applications. Flumethasone pivalate is a glucocorticoid corticosteroid and a corticosteroid ester. Flumetasone pivalate has anti-inflammatory, antipruritic, and vasoconstrictive activities .

HY-137024

15-Keto-PGA1	Angiotensin Receptor	Cardiovascular Disease
15-Keto-PGA1 is a metabolite of PGA1 and has significant vasoconstrictive effects. PGA1 is also a vasoconstrictor and is more potent than equivalent doses of prostaglandin F2α (PGF2α) and angiotensin II .

HY-W705539

DL-Phenylephrine-d3 hydrochloride (±)-Phenylephrine-d3 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease
DL-Phenylephrine-d₃ hydrochloride ((±)-Phenylephrine-d₃ hydrochloride) is the deuterium labeled DL-Phenylephrine hydrochloride (HY-W014726). DL-Phenylephrine ((±)-Phenylephrine) hydrochloride is a selective agonist of the alpha1-adrenergic receptor, exhibiting potent vasoconstrictive activity.

HY-B0878S

Halobetasol propionate-d5 BMY-30056-d₅; CGP-14458-d₅; Ulobetasol propionate-d₅	Isotope-Labeled Compounds Glucocorticoid Receptor	Inflammation/Immunology
Halobetasol propionate-d₅ (BMY-30056-d₅) is deuterium labeled Halobetasol propionate (HY-B0878). Halobetasol propionate (BMY-30056) is a synthetic glucocorticoid corticosteroid. Halobetasol propionate exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties. Halobetasol propionate can be used for the study of psoriasis .

HY-B0206S

Rizatriptan-d6 benzoate	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease
Rizatriptan-d₆ (benzoate) is the deuterium labeled Rizatriptan benzoate. Rizatriptan benzoate is the agonist for 5-HT_1B and 5-HT_1D. Rizatriptan benzoate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system ^.

HY-B0563AR

Ropivacaine hydrochloride monohydrate (Standard)	Reference Standards Sodium Channel Potassium Channel	Cardiovascular Disease Neurological Disease Cancer
Ropivacaine (hydrochloride monohydrate) (Standard) is the analytical standard of Ropivacaine (hydrochloride monohydrate). This product is intended for research and analytical applications. Ropivacaine hydrochloride monohydrate is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for regional anesthesia and neuropathic pain management in vivo .

HY-B0563C

Ropivacaine mesylate 5+ Cited Publications	Sodium Channel Potassium Channel	Cardiovascular Disease Neurological Disease Cancer
Ropivacaine mesylate is a long-acting amide local anaesthetic agent for a spinal block and effectively blocks neuropathic pain. Ropivacaine blocks impulse conduction via reversible inhibition of?sodium ion influx?in nerve fibressup>[1] . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel)?TREK-1?with an IC₅₀?of 402.7 μM in COS-7 cell's membrane .

HY-B0563BS

Ropivacaine-d7 hydrochloride	Isotope-Labeled Compounds Potassium Channel Sodium Channel	Neurological Disease
Ropivacaine-d₇ hydrochloride is a deuterium labeled Ropivacaine (hydrochloride) (HY-B0563B) . Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for neuropathic pain management in vivo .

HY-B0563R

Ropivacaine (Standard)	Reference Standards Sodium Channel Potassium Channel	Cardiovascular Disease Neurological Disease Cancer
Ropivacaine (Standard) is the analytical standard of Ropivacaine. This product is intended for research and analytical applications. Ropivacain is a potent sodium channel blocker. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane . Ropivacaine is used for the research of neuropathic pain management .

HY-10588R

Bay K 8644 (Standard) (±)-Bay K 8644 (Standard)	Reference Standards Calcium Channel	Cardiovascular Disease Neurological Disease
Bay K 8644 (Standard) is the analytical standard of Bay K 8644. This product is intended for research and analytical applications. Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644 . Bay K 8644 is a L-type Ca2+ channel agonist with an EC50 of 17.3 nM. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects .

HY-N0757R

8-O-Acetylharpagide (Standard)	Reference Standards Akt Bcl-2 Family Apoptosis Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
8-O-Acetylharpagide (Standard) is the analytical standard of 8-O-Acetylharpagide. This product is intended for research and analytical applications. 8-O-Acetylharpagide is an iridoid glycoside compound. 8-O-Acetylharpagide exhibits anti-aging activity at low doses and anticancer activity at high doses. 8-O-Acetylharpagide induces late-stage apoptosis and necrosis-like death in cancer cells, and downregulates anti-apoptotic proteins such as Akt, p-Akt and Bcl-2. 8-O-Acetylharpagide is mainly metabolized in rats via demethylation, hydrolysis and glucuronidation, and its active metabolites downregulate the AKT/NF-κB/MMP9 signaling axis. 8-O-Acetylharpagide exerts vasoconstrictive effects by activating vascular α-adrenoceptor.

HY-114986

6-Keto-PGE1 1 Publications Verification 6-keto-Prostaglandin E1	β-glucuronidase	Cardiovascular Disease
6-Keto-PGE1 (6-keto-Prostaglandin E1) is a biologically active derivative of PGE1. 6-Keto-PGE1 inhibits adenosine diphosphate-induced platelet aggregation. 6-Keto-PGE1 reduces cardiac afterload, decreases the accumulation of plasma myocardial depressant factor (MDF), lowers arterial blood pressure, dilates vascular beds, inhibits the vasoconstrictive response of vascular smooth muscle, and increases pulmonary compliance. 6-Keto-PGE1 directly stabilizes isolated cat liver lysosomes and significantly reduces the release of β-glucuronidase and cathepsin D. 6-Keto-PGE1 prolongs the survival time of traumatized rats and exerts protective effects through hemodynamic and cytoprotective actions. 6-Keto-PGE1 reduces central airway resistance. 6-Keto-PGE1 can be used in studies related to traumatic shock .

HY-135446

BQ-610	Endothelin Receptor	Cardiovascular Disease Endocrinology
BQ-610 is a selective antagonist of the endothelin A receptor (ETA receptor). BQ-610 specifically blocks the ETA receptor, competitively inhibiting the binding of endothelin-1 (ET-1) (a vasoconstrictive peptide) to the receptor, thereby blocking the effects of ET-1 such as vascular smooth muscle contraction, cell mitosis, and inhibition of hormone secretion. BQ-610 significantly alleviates cerebral vasospasm in rabbits. BQ-610 blocks the bronchial epithelial and pulmonary vascular cell proliferation caused by cigarette smoke in rat models. BQ-610 can delay the natural luteal regression in the cow's uterus. BQ-610 can be used for research on vasospasm, abnormal cell proliferation, and reproductive endocrine disorders .

Cat. No.	Product Name	Target	Research Area

HY-110183

Angiotensin A	Peptides	Cardiovascular Disease
Angiotensin A is a renin–angiotensin system (RAS) peptide that causes a vasoconstrictive effect dependent on AT₁ receptors. Angiotensin A elicits pressor and renal vasoconstrictor responses in normotensive and hypertensive rats .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0757

8-O-Acetylharpagide 1 Publications Verification	Infection Structural Classification other families Iridoids Classification of Application Fields Terpenoids Plants Inflammation/Immunology Disease Research Fields Source Classification	Akt Bcl-2 Family Apoptosis Adrenergic Receptor
8-O-Acetylharpagide is an orally active iridoid glycoside compound. 8-O-Acetylharpagide exhibits anti-aging activity at low doses and anticancer activity at high doses. 8-O-Acetylharpagide induces late-stage apoptosis and necrosis-like death in cancer cells, and downregulates anti-apoptotic proteins such as Akt, p-Akt and Bcl-2. 8-O-Acetylharpagide is mainly metabolized in rats via demethylation, hydrolysis and glucuronidation, and its active metabolites downregulate the AKT/NF-κB/MMP9 signaling axis. 8-O-Acetylharpagide exerts vasoconstrictive effects by activating vascular α-adrenoceptor .

HY-113248

3-Nitro-L-tyrosine	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Phenols Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Source Classification	Endogenous Metabolite Adrenergic Receptor Reactive Oxygen Species (ROS)
3-Nitro-L-tyrosine serves as a biomarker of oxidative stress. 3-Nitro-L-tyrosine attenuates the pressor and vasoconstrictive effects of angiotensin II by inhibiting the α₁-adrenergic receptor-mediated signaling pathway, and participates in hemodynamic regulation under pathological conditions such as inflammation and ischemia. 3-Nitro-L-tyrosine can be used in studies related to atherosclerosis, ischemia-reperfusion and sepsis .

HY-105697

Protoveratrine A NSC 7526; Protalba; Protoveratrin	Alkaloids Piperidine Alkaloids Veratrum nigrum Linn. Liliaceae Plants Source Classification	Glutamate Dehydrogenase (GLDH)
Protoveratrine A (NSC 7526; Protalba; Protoveratrin) is an alkaloid with strong cardiostimulant and vasoconstrictive effects, which can be used in the study of hypertension and other cardiovascular diseases .

HY-N9271R

Grifolin (Standard)	Microorganisms Phenols Polyphenols Source Classification	Apoptosis Reference Standards
Flumethasone pivalate (Standard) is the analytical standard of Flumethasone pivalate. This product is intended for research and analytical applications. Flumethasone pivalate is a glucocorticoid corticosteroid and a corticosteroid ester. Flumetasone pivalate has anti-inflammatory, antipruritic, and vasoconstrictive activities .

HY-N0757R

8-O-Acetylharpagide (Standard)	Structural Classification other families Iridoids Terpenoids Plants Source Classification	Reference Standards Akt Bcl-2 Family Apoptosis Adrenergic Receptor
8-O-Acetylharpagide (Standard) is the analytical standard of 8-O-Acetylharpagide. This product is intended for research and analytical applications. 8-O-Acetylharpagide is an iridoid glycoside compound. 8-O-Acetylharpagide exhibits anti-aging activity at low doses and anticancer activity at high doses. 8-O-Acetylharpagide induces late-stage apoptosis and necrosis-like death in cancer cells, and downregulates anti-apoptotic proteins such as Akt, p-Akt and Bcl-2. 8-O-Acetylharpagide is mainly metabolized in rats via demethylation, hydrolysis and glucuronidation, and its active metabolites downregulate the AKT/NF-κB/MMP9 signaling axis. 8-O-Acetylharpagide exerts vasoconstrictive effects by activating vascular α-adrenoceptor.

Cat. No.	Product Name	Chemical Structure

HY-W705539

DL-Phenylephrine-d3 hydrochloride
DL-Phenylephrine-d₃ hydrochloride ((±)-Phenylephrine-d₃ hydrochloride) is the deuterium labeled DL-Phenylephrine hydrochloride (HY-W014726). DL-Phenylephrine ((±)-Phenylephrine) hydrochloride is a selective agonist of the alpha1-adrenergic receptor, exhibiting potent vasoconstrictive activity.

HY-B0878S

Halobetasol propionate-d5
Halobetasol propionate-d₅ (BMY-30056-d₅) is deuterium labeled Halobetasol propionate (HY-B0878). Halobetasol propionate (BMY-30056) is a synthetic glucocorticoid corticosteroid. Halobetasol propionate exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties. Halobetasol propionate can be used for the study of psoriasis .

HY-B0206S

Rizatriptan-d6 benzoate
Rizatriptan-d₆ (benzoate) is the deuterium labeled Rizatriptan benzoate. Rizatriptan benzoate is the agonist for 5-HT_1B and 5-HT_1D. Rizatriptan benzoate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system ^.

HY-B0563BS

Ropivacaine-d7 hydrochloride
Ropivacaine-d₇ hydrochloride is a deuterium labeled Ropivacaine (hydrochloride) (HY-B0563B) . Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for neuropathic pain management in vivo .

Ropivacaine-d7 hydrochloride

Ropivacaine-d₇ hydrochloride is a deuterium labeled Ropivacaine (hydrochloride) (HY-B0563B) . Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for neuropathic pain management in vivo .

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vasoconstrictive

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