Secaubryenol
Secaubryenol is a class of 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla. Secaubryenol does not display any cytotoxic effect at a dose of 10 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 925932-08-7
- Formula: C30H48O3
- Molecular Weight:456.70
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Endogenous Metabolite Isoforms
More
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
>5 μg/mL
Compound: 4
|
Cytotoxicity against human BT474 cells after 3 days by MTT assay
Cytotoxicity against human BT474 cells after 3 days by MTT assay
|
[PMID: 20028108] |
| HepG2 | IC50 |
>5 μg/mL
Compound: 4
|
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
|
[PMID: 20028108] |
| SW-620 | IC50 |
>5 μg/mL
Compound: 4
|
Cytotoxicity against human SW620 cells after 3 days by MTT assay
Cytotoxicity against human SW620 cells after 3 days by MTT assay
|
[PMID: 20028108] |
Secaubryenol exhibits IC50 value over 100 μM against tumor cell lines (MCF-7 (breast cancer cells, ER (estrogen receptor) positive), MDA (breast cancer cells, ER negative), PC-3 (prostate cancer cells), and HeLa (cervical cancer cells))[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 925932-08-7
-
Molecular Weight 456.70
-
Formula C30H48O3
-
SMILES
[H][C@]1([C@H](C)CC/C=C(C)/C)CC[C@]2(C)[C@]1(C)CC[C@]34[C@@]2([H])CC[C@@H](C(CO)=C)[C@@]3(CCC(O)=O)C4
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Grougnet R, et al. Cytotoxic 3,4-seco-cycloartane triterpenes from the exudate of Gardenia tubifera. J Nat Prod. 2006 Dec;69(12):1711-4. [Content Brief]
[2]. Gilardoni G, et al. New 3,4-Secocycloartane and 3,4-Secodammarane Triterpenes from the Ecuadorian Plant Coussarea macrophylla. Chem Biodivers. 2015 Jun;12(6):946-54. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Secaubryenol Related Classifications
HY-N1272 Related Classifications
Powered by Bioz