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Art. -Nr.: HY-119697

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Setosusin

(Synonyms: (+)-Setosusin)

Setosusin ((+)-Setosusin) is a fungal meroditerpenoid featuring a unique spiro-fused 3(2H)-furanone moiety.

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CAS. Nr.: 182926-45-0
Formel: C₂₉H₃₈O₈
Molecular Weight:514.61

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Setosusin Chemical Structure

CAS. Nr.: 182926-45-0

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Use of MCE Products

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Bioz

Biologische Aktivität

Beschreibung

Setosusin ((+)-Setosusin) is a fungal meroditerpenoid featuring a unique spiro-fused 3(2H)-furanone moiety^[1].

IC₅₀ & Target^[1]

Microbial Metabolite

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
PC-12	EC₅₀	112.6 μM Compound: 10	Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregate-induced toxicity in rat PC12 cells preincubated for 1 hr followed by amyloid beta challenge measured after 24 hrs by MTT assay Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregate-induced toxicity in rat PC12 cells preincubated for 1 hr followed by amyloid beta challenge measured after 24 hrs by MTT assay	[PMID: 26517152]

Chemical Information

CAS. Nr. 182926-45-0
Molecular Weight 514.61
Formel C₂₉H₃₈O₈
SMILES

CC(C)(O1)[C@]2([C@@](C)([C@@]3([C@@](C)(CC2)[C@@]4(C(C)=CC3)C[C@]5(C(O4)=O)C(C(C)=C(O5)C)=O)[H])[C@H](CC1=O)OC(C)=O)[H]
Synonyms

(+)-Setosusin
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
ascomycete
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wei X, et al. Molecular and Computational Bases for Spirofuranone Formation in Setosusin Biosynthesis. J Am Chem Soc. 2021;143(42):17708-17715. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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