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Cat. No.: HY-N12286

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Denthyrsinin

Name: Denthyrsinin
Brand: MedChemExpress
SKU: HY-N12286
Price: 250.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Denthyrsinin is a phenanthrene compound discovered from Dendrobium. Denthyrsinin has cytotoxic effects on various cancer cells. Denthyrsinin can be used in research related to cervical cancer, leukemia, and breast cancer.

For research use only. We do not sell to patients.

CAS No.: 118169-17-8
Formula: C₁₇H₁₆O₅
Molecular Weight:300.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (280 KB)

Denthyrsinin Chemical Structure

CAS No.: 118169-17-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Denthyrsinin is a phenanthrene compound discovered from Dendrobium. Denthyrsinin has cytotoxic effects on various cancer cells. Denthyrsinin can be used in research related to cervical cancer, leukemia, and breast cancer^[1]^[2]^[3].

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC50	2.7 μM	Cytotoxicity against human Hela cells assessed as 50% inhibition of cell growth after 72 hrs incubation by MTT assay. Cytotoxicity against human Hela cells assessed as 50% inhibition of cell growth after 72 hrs incubation by MTT assay.	15913675
K562	IC50	2.3 μM	Cytotoxicity against human K-562 cells assessed as 50% inhibition of cell growth after 72 hrs incubation by MTT assay. Cytotoxicity against human K-562 cells assessed as 50% inhibition of cell growth after 72 hrs incubation by MTT assay.	15913675
MCF7	IC50	4.8 μM	Cytotoxicity against human MCF-7 cells assessed as 50% inhibition of cell growth after 72 hrs incubation by MTT assay. Cytotoxicity against human MCF-7 cells assessed as 50% inhibition of cell growth after 72 hrs incubation by MTT assay.	15913675

In Vitro

Anti-cancer

Denthyrsinin (72 h) shows cytotoxic activity against Hela (IC₅₀ 2.7 μM), K-562 (IC₅₀ 2.3 μM), and MCF-7 (IC₅₀ 4.8 μM) cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 118169-17-8
Molecular Weight 300.31
Formula C₁₇H₁₆O₅
SMILES

OC(C=CC1=C2C(OC)=C3O)=C(OC)C1=CC=C2C=C3OC
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (280 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang GN, et al. Bi-bicyclic and bi-tricyclic compounds from Dendrobium thyrsiflorum. Phytochemistry. 2005 May;66(10):1113-20.

[2]. Araújo-Lima CF, et al. Metabolomic analysis of Cyrtopodium glutiniferum extract by UHPLC-MS/MS and in vitro antiproliferative and genotoxicity assessment. Journal of ethnopharmacology. 2020 May 10;253:112607.

[3]. Nam B, et al. Chemical and Biological Profiles of in Two Different Species, Their Hybrid, and Gamma-Irradiated Mutant Lines of the Hybrid Based on LC-QToF MS and Cytotoxicity Analysis. Plants (Basel, Switzerland). 2021 Jul 05;10(7):1376.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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