Trx-red
Based on 1 Customer Validation
Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm).
For research use only. We do not sell to patients.
- Purity: 96.58%
- CAS No.: 2368978-96-3
- Formula: C29H32ClN3O12S2
- Molecular Weight:714.16
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Trx-red (NBL-SS) displayed multiple favorable properties, such as red emission, fast response, and high fluorescence signal. Thioredoxin (Trx) is a ubiquitous redox-regulating protein essentially involved in cell growth, differentiation, and death[1].
When HeLa cells are incubated with Trx-red (NBL-SS; 5 μM; 0-30 min), a clear time-dependent increase of the fluorescence is observed[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
660
615
Chemical Information
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CAS No. 2368978-96-3
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Appearance Oil
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Molecular Weight 714.16
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Formula C29H32ClN3O12S2
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Color Dark purple to black
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SMILES
O=C(NC1=CC(OC2=C/3)=C(C4=C1C=CC=C4)N=C2C=CC3=[N+](CCC(OC)=O)/CCC(OC)=O)OCCSSCCO.O=Cl(=O)([O-])=O
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Synonyms
NBL-SS perchlorate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 50 mg/mL (70.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4002 mL | 7.0012 mL | 14.0025 mL | 35.0062 mL |
| 5 mM | 0.2800 mL | 1.4002 mL | 2.8005 mL | 7.0012 mL | |
| 10 mM | 0.1400 mL | 0.7001 mL | 1.4002 mL | 3.5006 mL | |
| 15 mM | 0.0933 mL | 0.4667 mL | 0.9335 mL | 2.3337 mL | |
| 20 mM | 0.0700 mL | 0.3501 mL | 0.7001 mL | 1.7503 mL | |
| 25 mM | 0.0560 mL | 0.2800 mL | 0.5601 mL | 1.4002 mL | |
| 30 mM | 0.0467 mL | 0.2334 mL | 0.4667 mL | 1.1669 mL | |
| 40 mM | 0.0350 mL | 0.1750 mL | 0.3501 mL | 0.8752 mL | |
| 50 mM | 0.0280 mL | 0.1400 mL | 0.2800 mL | 0.7001 mL | |
| 60 mM | 0.0233 mL | 0.1167 mL | 0.2334 mL | 0.5834 mL |
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