SHP2-IN-32
SHP2-IN-32 (compound C6) is an orally active, allosteric SHP2 inhibitor with an IC50 value of 0.13 nM. SHP2-IN-32 exhibits antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 3043685-80-6
- Formula: C29H27ClN6O2S
- Molecular Weight:559.08
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50:0.13 nM (SHP2)[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MV4-11 | IC50 |
3.5 nM
Compound: C6
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Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK-8 assay
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[PMID: 39303516] |
Chemical Information
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CAS No. 3043685-80-6
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Molecular Weight 559.08
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Formula C29H27ClN6O2S
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SMILES
N[C@@H]1C2=C(C=CC=C2)CC13CCN(C4=NC=C(SC5=C(Cl)C(NC(C6=C(O)C=CN=C6)=O)=CC=C5)N=C4)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SHP2-IN-32 Related Classifications
HY-169111 Related Classifications
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