SOS1-IN-19
SOS1-IN-19 (Compound 10i) is a potent inhibitor of SOS1 (Son of Sevenless 1) with an IC50 value of 165.2 nM. SOS1-IN-19 blocks KRAS activation by preventing GDP/GTP exchange in KRAS signaling pathway. SOS1-IN-19 is promising for research of KRAS-driven cancers (e.g., NSCLC and colorectal cancer).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C24H29F3N6O2
- Peso molecular:490.52
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Chemical Information
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Peso molecular 490.52
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Fòrmula C24H29F3N6O2
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SMILES
COC1=C(OC)C=C2C(N=C(N3CC(N(C)C)C3)N=C2N[C@H](C)C4=CC(N)=CC(C(F)(F)F)=C4)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)