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Cat. No.: HY-184930

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SOS1 ligand-4

SOS1 ligand-4 is a SOS1 ligand with a K_d value of 570 nM. SOS1 ligand-4 is applicable for cancer research.

For research use only. We do not sell to patients.

Formula: C₁₆H₁₂F₄N₂O₂S
Molecular Weight:372.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

SOS1 ligand-4 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

SOS1 ligand-4 is a SOS1 ligand with a K_d value of 570 nM. SOS1 ligand-4 is applicable for cancer research^[1].

In Vitro

SOS1 ligand-4 (Compound 6f) (0.1 nM-10 mM) binds to purified SOS1 protein, and its dissociation constant K_d is determined as 0.57 μM by microscale thermophoresis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 372.34
Formula C₁₆H₁₂F₄N₂O₂S
SMILES

O=S1(C2=CC=CC=C2C(N[C@H](C)C3=C(F)C(C(F)(F)F)=CC=C3)=N1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Pereira, et al. Structural and biophysical characterization of aminobenzo[d]isothiazole 1,1-dioxide SOS1 ligands. ACS Med Chem Lett. 2016;7(8):797-802.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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