Sp1-IN-1
Sp1-IN-1 is a selective specificity protein 1 (Sp1) inhibitor. Sp1-IN-1 inhibits the proliferation of Hela cells and MCF-7 cells. Sp1-IN-1 can be used to the studies of cervical cancer and breast cancer.
For research use only. We do not sell to patients.
- Formula: C37H54O5
- Molecular Weight:578.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Sp1-IN-1 (Compound I8) inhibits Hela and MCF-7 cell proliferation with IC50s of 10.56 and 11.77 μM[1].
Sp1-IN-1 (3-12 μM, 48 h) dose-dependently down-regulates the expression of Sp1 protein in MCF-7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MCF-7 cells
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Concentration:3, 6, 12 μM
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Incubation Time:48 h
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Result:Dose-dependently down-regulated the expression of Sp1 protein.
Chemical Information
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Molecular Weight 578.82
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Formula C37H54O5
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SMILES
C[C@@H]([C@@H](C1C2=CCC3[C@@]([C@@]2(CC4)C)(C)CCC5[C@](CO)(COC(C[C@]35C)O)C)C)CC[C@@]14C(OCC6=CC=CC=C6)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)