2. GPCR/G Protein
  3. TSH Receptor
  4. SYD5115

SYD5115 is an orally available TSH-R antagonist,.

For research use only. We do not sell to patients.

SYD5115 Chemical Structure

SYD5115 Chemical Structure

Size Price Stock Quantity
5 mg USD 750 Get quote 9 - 10 weeks 9 - 10 weeks 8 - 9 weeks
10 mg USD 1200 Get quote 9 - 10 weeks 9 - 10 weeks 8 - 9 weeks
25 mg USD 2550 Get quote 9 - 10 weeks 9 - 10 weeks 8 - 9 weeks
50 mg USD 4050 Get quote 9 - 10 weeks 9 - 10 weeks 8 - 9 weeks
100 mg USD 6500 Get quote 9 - 10 weeks 9 - 10 weeks 8 - 9 weeks
200 mg   Get quote  
500 mg   Get quote  
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SYD5115 Related Antibodies

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Description

SYD5115 is an orally available TSH-R antagonist,[1][2].

In Vitro

SYD5115 (0.1 nM-10 μM) blocks M22-induced cAMP production with IC50s of 22 nM in rat FRTL5 and HEK293-hTSHR cells, respectively[1] .
Note: M22 is a stimulating autoantibody to the human monoclonal TSH receptor (TSHR), and another autoantibody is K1-70 (blocking) [2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SYD5115 Related Antibodies
Molecular Weight

438.51

Formula

C22H32F2N4O3
Unlabeled CAS

SMILES

O=C(O[C@H](C(C)(C)C)C)NC1=NC=C(N(C(C)=O)C2(C)C)C(C32CCC(F)(F)CC3)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SYD5115 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SYD5115SYD 5115SYD-5115TSH ReceptorThyrotropin receptorThyroid-stimulating hormone ReceptorGPCR-antagonistGraves’ diseaseSmall molecule antagonistTSH-R antagonistThyroid stimulating hormone receptorInhibitorinhibitorinhibit

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HY-158100
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