1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor
  3. TACA

TACA (Synonyms: trans-4-Aminocrotonic acid)

Cat. No.: HY-100800
Handling Instructions

TACA (trans-4-Aminocrotonic acid) is a potent agonist of GABAA and GABAC receptors (KD= 0.6 μM). TACA also is GABA uptake inhibitor and substrate for GABA-T. TACA produces late biphasic responses in the MPG neurons.

For research use only. We do not sell to patients.

TACA Chemical Structure

TACA Chemical Structure

CAS No. : 38090-53-8

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Description

TACA (trans-4-Aminocrotonic acid) is a potent agonist of GABAA and GABAC receptors (KD= 0.6 μM). TACA also is GABA uptake inhibitor and substrate for GABA-T. TACA produces late biphasic responses in the MPG neurons[1][2][3].

IC50 & Target

KD: 0.6 μM (GABAC)[1].

In Vivo

TACA is a potent competitive inhibitor of GABA uptake in rat brain slices and thus is possibly a substrate for the GABA uptake system[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

101.10

Formula

C₄H₇NO₂

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
TACA
Cat. No.:
HY-100800
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