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Cat. No.: HY-184040

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TDO-IN-3

TDO-IN-3 (compound 20) is an IDO1/TDO inhibitor with IC₅₀ values of 4.12 and 0.12 μM, respectively.

For research use only. We do not sell to patients.

CAS No.: 2490673-04-4
Formula: C₁₄H₁₈BrN₃O
Molecular Weight:324.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TDO-IN-3 Chemical Structure

CAS No.: 2490673-04-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

TDO-IN-3 (compound 20) is an IDO1/TDO inhibitor with IC₅₀ values of 4.12 and 0.12 μM, respectively^[1].

IC₅₀ & Target^[1]

IDO1

4.12 μM (IC₅₀)

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms :

Chemical Information

CAS No. 2490673-04-4
Molecular Weight 324.22
Formula C₁₄H₁₈BrN₃O
SMILES

BrC1=CC(NCC2C(CCCC2)O)=C3C(NN=C3)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ning XL, et al. X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's Disease. J Med Chem. 2021;64(12):8303-8332. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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TDO-IN-3

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

TDO-IN-3 Related Classifications

HY-184040 Related Classifications