1. Cell Cycle/DNA Damage
  2. Telomerase
  3. Telomerase-IN-2

Telomerase-IN-2 

Cat. No.: HY-126482 Purity: 98.71%
Handling Instructions

Telomerase-IN-2 is a telomerase inhibitor, and inhibits telomerase activity by decreasing expression of dyskerin, with an IC50 of 0.89 µM. Anti-cancer activity.

For research use only. We do not sell to patients.

Telomerase-IN-2 Chemical Structure

Telomerase-IN-2 Chemical Structure

CAS No. : 1610878-54-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 697 In-stock
Estimated Time of Arrival: December 31
1 mg USD 165 In-stock
Estimated Time of Arrival: December 31
5 mg USD 500 In-stock
Estimated Time of Arrival: December 31
10 mg USD 850 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1705 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2900 In-stock
Estimated Time of Arrival: December 31
100 mg USD 4930 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

Telomerase-IN-2 is a telomerase inhibitor, and inhibits telomerase activity by decreasing expression of dyskerin, with an IC50 of 0.89 µM. Anti-cancer activity[1].

IC50 & Target

IC50: 0.89 µM (Telomerase)[1]

Molecular Weight

633.69

Formula

C₃₄H₃₉N₃O₉

CAS No.

1610878-54-0

SMILES

O=C1C(OCCCCN2CCN(C(C3=CC=NC=C3)=O)CC2)=C(C4=CC(OC)=C(OC)C(OC)=C4)OC5=CC(OC)=CC(OC)=C15

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (394.51 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5781 mL 7.8903 mL 15.7806 mL
5 mM 0.3156 mL 1.5781 mL 3.1561 mL
10 mM 0.1578 mL 0.7890 mL 1.5781 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (3.28 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.28 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Telomerase-IN-2TelomeraseInhibitorinhibitorinhibit

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Product name:
Telomerase-IN-2
Cat. No.:
HY-126482
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