Tetradifon (Standard)
Tetradifon (Standard) is the analytical standard of Tetradifon (HY-119725). This product is intended for research and analytical applications. Tetradifon is a broad-spectrum organochlorine insecticide and an inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), which can be used to control a variety of mites. Tetradifon inhibits energy-related activities such as ADP-stimulated respiration, DNP and Mg2+-stimulated ATPase, with an IC50 of 4.5-27 nmoL/mg mitochondrial protein. Tetradifon exerts oligomycin-like activity by inhibiting the oxidative phosphorylation process, inducing oxidative stress and interfering with bone metabolism. Tetradifon is currently mainly used in the research of mitochondrial function regulation, bone remodeling mechanism and nephrotoxicity of environmental pollutants.
For research use only. We do not sell to patients.
- CAS No.: 116-29-0
- Formula: C12H6Cl4O2S
- Molecular Weight:356.05
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 116-29-0
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Molecular Weight 356.05
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Formula C12H6Cl4O2S
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SMILES
O=S(C1=C(C=C(C(Cl)=C1)Cl)Cl)(C2=CC=C(C=C2)Cl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Desaiah D, et al. Tetradifon (tedion R ): a specific inhibitor of Mg 2+ dependent mitochondrial adenosine triphosphatase activity. Life Sci II. 1972 Apr 8;11(7):389-95. [Content Brief]
[2]. Bustamante E, et al. Tetradifon: an oligomycin-like inhibitor of energy-linked activities of rat liver mitochondria. Biochem Biophys Res Commun. 1973 Mar 17;51(2):292-8. [Content Brief]
[3]. Badraoui R, et al. Effect of subchronic exposure to tetradifon on bone remodelling and metabolism in female rat. C R Biol. 2007 Dec;330(12):897-904. [Content Brief]
[4]. Badraoui R, et al. Nephrotoxic effect of tetradifon in rats: a biochemical and histomorphometric study. Exp Toxicol Pathol. 2012 Sep;64(6):645-50. [Content Brief]
[5]. Fatemeh Ganjeizadeh Rohani, et al. Electropolymerized MIP With MWCNTs on Stir Bar Using Multivariate Optimization for Tetradifon Detection in Date. Pharm Nanotechnol. 2019;7(5):404-417. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tetradifon (Standard) Related Classifications
HY-119725R Related Classifications
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