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  3. Drug Derivative
  4. Thiosildenafil

Thiosildenafil, a Sildenafil (HY-15025) analogue, is a compound found in health supplement.

For research use only. We do not sell to patients.

Thiosildenafil

Thiosildenafil Chemical Structure

CAS No. : 479073-79-5

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Based on 1 publication(s) in Google Scholar

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Thiosildenafil Related Antibodies

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Description

Thiosildenafil, a Sildenafil (HY-15025) analogue, is a compound found in health supplement[1][2].

Molecular Weight

490.64

Formula

C22H30N6O3S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

S=C1C2=C(N=C(N1)C3=C(C=CC(S(=O)(N4CCN(CC4)C)=O)=C3)OCC)C(CCC)=NN2C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (101.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0382 mL 10.1908 mL 20.3815 mL
5 mM 0.4076 mL 2.0382 mL 4.0763 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0382 mL 10.1908 mL 20.3815 mL 50.9539 mL
5 mM 0.4076 mL 2.0382 mL 4.0763 mL 10.1908 mL
10 mM 0.2038 mL 1.0191 mL 2.0382 mL 5.0954 mL
15 mM 0.1359 mL 0.6794 mL 1.3588 mL 3.3969 mL
20 mM 0.1019 mL 0.5095 mL 1.0191 mL 2.5477 mL
25 mM 0.0815 mL 0.4076 mL 0.8153 mL 2.0382 mL
30 mM 0.0679 mL 0.3397 mL 0.6794 mL 1.6985 mL
40 mM 0.0510 mL 0.2548 mL 0.5095 mL 1.2738 mL
50 mM 0.0408 mL 0.2038 mL 0.4076 mL 1.0191 mL
60 mM 0.0340 mL 0.1698 mL 0.3397 mL 0.8492 mL
80 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.6369 mL
100 mM 0.0204 mL 0.1019 mL 0.2038 mL 0.5095 mL
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Thiosildenafil Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thiosildenafil479073-79-5Drug DerivativeDrug derivativehealth supplement,SildenafilInhibitorinhibitorinhibit

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