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TNIK-IN-4 is a potent TNIK inhibitor with IC50 of 0.61 μM. TNIK-IN-4 has inhibitory activity against typical colorectal cancer cell line HCT116.

For research use only. We do not sell to patients.

TNIK-IN-4 Chemical Structure

TNIK-IN-4 Chemical Structure

CAS No. : 2754266-04-9

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TNIK-IN-4 Related Antibodies

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Description

TNIK-IN-4 is a potent TNIK inhibitor with IC50 of 0.61 μM. TNIK-IN-4 has inhibitory activity against typical colorectal cancer cell line HCT116[1].

IC50 & Target

IC50: 0.61 μM (TNIK)[1]
In Vitro

TNIK-IN-4 (compound 5a) (0.4-100 μM; 72 hours) has inhibitory activity against typical colorectal cancer cell line HCT116 with IC50 of 36.423 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

TNIK-IN-4 Related Antibodies

Cell Proliferation Assay

Cell Line: HCT116 cells[1]
Concentration: 0.4, 1.2, 3.7, 11.1, 33.3 and 100 μM
Incubation Time: 72 hours
Result: Showed inhibitory activity against typical colorectal cancer cell line HCT116 with IC50 of 36.423 μM.
Molecular Weight

365.36

Formula

C20H16FN3O3
CAS No.
SMILES

O=C1OC2=CC(C3=CC(OC)=C(N)N=C3)=CC=C2N1CC4=CC=C(F)C=C4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TNIK-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TNIK-IN-42754266-04-9OthersTNIKColorectal cancerHCT116?cellsInhibitorinhibitorinhibit

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HY-143436
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